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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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Data corrente: |
18/07/2025 |
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Data da última atualização: |
18/07/2025 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BEZERRA, A. P. M.; MOREIRA, A. C. DE O. M.; DIONISIO, A. P.; ANDRADE, B. K. DE M.; OLIVEIRA, K. A DE; ALVES FILHO, E. G.; BRITO, E. S. de; OLIVEIRA, A. C. DE; SILVA, F. L. DA; VIANA, J. D. DA R.; ABREU, F. A. P. de; CARIOCA, A. A. F. |
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Afiliação: |
ANA PAULA MOREIRA BEZERRA, RENORBIO; ANA CRISTINA DE OLIVEIRA MONTEIRO MOREIRA, UNIFOR; ANA PAULA DIONISIO, CNPAT; BRUNA KELLY DE MEDEIROS ANDRADE, STATE UNIVERSITY OF CEARÁ; KECIANY ALVES DE OLIVEIRA, STATE UNIVERSITY OF CEARÁ; ELENILSON GODOY ALVES FILHO, FEDERAL UNIVERSITY OF CEARÁ; EDY SOUSA DE BRITO, CNAT; ARICLÉCIO CUNHA DE OLIVEIRA, CEARÁ STATE UNIVERSITY; FRANCISCO LEOMAR DA SILVA, FEDERAL UNIVERSITY OF CEARÁ; JOSÉ DIOGO DA ROCHA VIANA, FEDERAL UNIVERSITY OF CEARÁ; FERNANDO ANTONIO PINTO DE ABREU, CNPAT; ANTÔNIO AUGUSTO FERREIRA CARIOCA, UNIFOR. |
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Título: |
¹H NMR-based metabolomic study of the effects of yacon syrup supplementation on high-fat diet in rats. |
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Ano de publicação: |
2025 |
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Fonte/Imprenta: |
International Journal of Food Science and Technology, v. 60, n. 1, vvaf078 , 2025. |
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DOI: |
https://doi.org/10.1093/ijfood/vvaf078 |
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Idioma: |
Inglês |
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Conteúdo: |
The effect of yacon (Smallanthus sonchifolius) syrup supplementation on the metabolomic profile of plasma from rats with hyperlipidemic diet was investigated. Male rats were distributed into four groups containing 10 animals each: control diet (animals fed with standard diet—12.5% of humidity, 23% of crude protein, 4% of ethereal extract, 9% mineral material, and 5% of crude fibre); high-fat diet (HFD— 37.5% standard feed, 25% milk chocolate, 25% unsalted and peeled peanuts and 12.5% cornstarch cookie, totalling 14% protein, 38% carbohydrate, and 48% lipids); HFD +1% FOS, and HFD +2% FOS, which received HFD for 5 weeks and then, received HDF supplemented with 1% and 2% FOS (HFDY1 and HFDY2, respectively). The HFDY2 samples showed decreased fatty acids, glucose, and glycerol compared to HFD. The presence of short-chain fatty acids in the HFDY2 samples highlighted the functional action of the prebiotic, which was not observed in the HFDY1 group. Additionally, HFD can lead to disturbed glycolysis and altered anaerobic metabolism based on increased lactate. Glycerol, glutamate, and glutamine were associated as biomarkers for hyperlipidemia, evidencing that supplementation with 2% FOS was not effective in mitigating the effects of an HFD. |
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Palavras-Chave: |
Biomarcadores; Frutooligossacarídeos; Metabolômica; Prebiótico; Yacon. |
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Thesaurus Nal: |
Biomarkers; Fructooligosaccharides; Metabolomics; Prebiotics; Smallanthus sonchifolius. |
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Categoria do assunto: |
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W Química e Física |
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Marc: |
LEADER 02446naa a2200385 a 4500
001 2177387
005 2025-07-18
008 2025 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1093/ijfood/vvaf078$2DOI
100 1 $aBEZERRA, A. P. M.
245 $a¹H NMR-based metabolomic study of the effects of yacon syrup supplementation on high-fat diet in rats.$h[electronic resource]
260 $c2025
520 $aThe effect of yacon (Smallanthus sonchifolius) syrup supplementation on the metabolomic profile of plasma from rats with hyperlipidemic diet was investigated. Male rats were distributed into four groups containing 10 animals each: control diet (animals fed with standard diet—12.5% of humidity, 23% of crude protein, 4% of ethereal extract, 9% mineral material, and 5% of crude fibre); high-fat diet (HFD— 37.5% standard feed, 25% milk chocolate, 25% unsalted and peeled peanuts and 12.5% cornstarch cookie, totalling 14% protein, 38% carbohydrate, and 48% lipids); HFD +1% FOS, and HFD +2% FOS, which received HFD for 5 weeks and then, received HDF supplemented with 1% and 2% FOS (HFDY1 and HFDY2, respectively). The HFDY2 samples showed decreased fatty acids, glucose, and glycerol compared to HFD. The presence of short-chain fatty acids in the HFDY2 samples highlighted the functional action of the prebiotic, which was not observed in the HFDY1 group. Additionally, HFD can lead to disturbed glycolysis and altered anaerobic metabolism based on increased lactate. Glycerol, glutamate, and glutamine were associated as biomarkers for hyperlipidemia, evidencing that supplementation with 2% FOS was not effective in mitigating the effects of an HFD.
650 $aBiomarkers
650 $aFructooligosaccharides
650 $aMetabolomics
650 $aPrebiotics
650 $aSmallanthus sonchifolius
653 $aBiomarcadores
653 $aFrutooligossacarídeos
653 $aMetabolômica
653 $aPrebiótico
653 $aYacon
700 1 $aMOREIRA, A. C. DE O. M.
700 1 $aDIONISIO, A. P.
700 1 $aANDRADE, B. K. DE M.
700 1 $aOLIVEIRA, K. A DE
700 1 $aALVES FILHO, E. G.
700 1 $aBRITO, E. S. de
700 1 $aOLIVEIRA, A. C. DE
700 1 $aSILVA, F. L. DA
700 1 $aVIANA, J. D. DA R.
700 1 $aABREU, F. A. P. de
700 1 $aCARIOCA, A. A. F.
773 $tInternational Journal of Food Science and Technology$gv. 60, n. 1, vvaf078 , 2025.
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Registro original: |
Embrapa Agroindústria Tropical (CNPAT) |
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