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Registro Completo |
Biblioteca(s): |
Embrapa Semiárido. |
Data corrente: |
11/02/2021 |
Data da última atualização: |
12/02/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
SILVA, C. B. da; DUARTE, D. S.; SOUZA, A. V. de; ASSIS, O. B. G. de; BRITTO, D. de. |
Afiliação: |
Cristina Barbosa da Silva; Dirliane Santos Duarte; ANA VALERIA VIEIRA DE SOUZA, CPATSA; ODILIO BENEDITO GARRIDO DE ASSIS, CNPDIA; DOUGLAS DE BRITTO, CPATSA. |
Título: |
Synthesis of chitosan polysaccharide nanoparticles for skin grape extract stabilization. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Brazilian Journal of Development, v. 6, n. 4, p. 17913-17930, 2020. |
Idioma: |
Inglês |
Conteúdo: |
Nanoparticles obtained by chitosan and tripolyphosphatehas been largely studied due to its entrapment characteristics. However, several parameters can influence the synthesis and encapsulationprocesses. In this way, this work proposed to study the nanoparticle formation with chitosan and tripolyphosphate in function of the acid concentration (1.0; 0.5 and0.1%) and the kind of the acid (hydrochloric and acetic). Conductometric and Potentiometric techniques showed that the reactional system was very dependent on the pH variation. The best condition, both for HCl and acetic acid, was achieved for systems with lower pH variation. For such systems, Dynamic Light Scattering technique showed formation of nanoparticle with the lowest size (135±7 nm) and higher stability (zeta potential near 30 mV). Also, by Scanning Electronic Microscopy, such systems exhibited good morphological aspect, with nanoparticles having spherical shape and lower level of agglomeration. The cryoprotection with sucrose solution before freeze-drying was fundamental to get samples with the improved re-suspension ability and preserved nanoparticle character. By UV-visible spectrophotometry, both HCl and acetic acid-based systems resulted in nanoparticles with good polyphenols encapsulation efficiency (~70%). The release profile was pH-dependent. In this way, the chitosan and tripolyphosphate ionic gelification need an accurate pH control both in the synthesis and in the encapsulation-release processes. |
Palavras-Chave: |
Casca de uva; Encapsulamento; Hidrogel; Nanopartículas; Polieletrólito; Polifenóis; Quitosana; Reticulação iônica. |
Thesagro: |
Uva. |
Thesaurus Nal: |
Grapes. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/221168/1/Synthesis-of-chitosan-polysaccharide-nanoparticle-2020.pdf
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Marc: |
LEADER 02306naa a2200289 a 4500 001 2130000 005 2021-02-12 008 2020 bl uuuu u00u1 u #d 100 1 $aSILVA, C. B. da 245 $aSynthesis of chitosan polysaccharide nanoparticles for skin grape extract stabilization.$h[electronic resource] 260 $c2020 520 $aNanoparticles obtained by chitosan and tripolyphosphatehas been largely studied due to its entrapment characteristics. However, several parameters can influence the synthesis and encapsulationprocesses. In this way, this work proposed to study the nanoparticle formation with chitosan and tripolyphosphate in function of the acid concentration (1.0; 0.5 and0.1%) and the kind of the acid (hydrochloric and acetic). Conductometric and Potentiometric techniques showed that the reactional system was very dependent on the pH variation. The best condition, both for HCl and acetic acid, was achieved for systems with lower pH variation. For such systems, Dynamic Light Scattering technique showed formation of nanoparticle with the lowest size (135±7 nm) and higher stability (zeta potential near 30 mV). Also, by Scanning Electronic Microscopy, such systems exhibited good morphological aspect, with nanoparticles having spherical shape and lower level of agglomeration. The cryoprotection with sucrose solution before freeze-drying was fundamental to get samples with the improved re-suspension ability and preserved nanoparticle character. By UV-visible spectrophotometry, both HCl and acetic acid-based systems resulted in nanoparticles with good polyphenols encapsulation efficiency (~70%). The release profile was pH-dependent. In this way, the chitosan and tripolyphosphate ionic gelification need an accurate pH control both in the synthesis and in the encapsulation-release processes. 650 $aGrapes 650 $aUva 653 $aCasca de uva 653 $aEncapsulamento 653 $aHidrogel 653 $aNanopartículas 653 $aPolieletrólito 653 $aPolifenóis 653 $aQuitosana 653 $aReticulação iônica 700 1 $aDUARTE, D. S. 700 1 $aSOUZA, A. V. de 700 1 $aASSIS, O. B. G. de 700 1 $aBRITTO, D. de 773 $tBrazilian Journal of Development$gv. 6, n. 4, p. 17913-17930, 2020.
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Embrapa Semiárido (CPATSA) |
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Registros recuperados : 13 | |
7. | | PINOLA, F. G.; BRITTO, D. de; LUNDSTEDT, L. M.; ASSIS, O. B. G. de; MATTOSO, L. H. C. Estudo da estabilidade de vitaminas nanoencapsuladas em suspensão aquosa e em substratos sólidos (fubá). In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 8, 2014, Juiz de fora. Anais... São Carlos: Embrapa Instrumentação; Campo Grande: Embrapa Gado de Corte; Juiz de Fora: Embrapa Gado de Leite, 2014. p. 512-516. Editores: Maria Alice Martins, Humberto de Mello Brandão, Marlene de Barros Coelho, Daniel Souza Corrêa, Caue Ribeiro, Luiz Henrique Capparelli Mattoso.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Instrumentação; Embrapa Semiárido. |
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10. | | BRITTO, D. de; MOURA, M. R de; AOUADA, F. A.; PINOLA, F. G.; LUNDSTEDT, L. M.; ASSIS, O. B. G. de; MATTOSO, L. H. C. Entrapment characteristics of hydrosoluble vitamins loaded into chitosan and N,N,N-Trimethyl chitosan nanoparticles. Macromolecular Research, v. 22, n. 12, p. 1261-1267, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Semiárido. |
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11. | | BRITTO, D. de, MOURA, M. R. de, AOUADA, F. A. PINOLA, F. G. LUNDSTEDT, L. M.; ASSIS, O. B. G.; MATTOSO, L. H. C. Nanopartículas de trimetil quitosana. I-caracterização e eficácia de encapsulamento de vitaminas hidrossolúveis. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 8, 2014, Juiz de fora. Anais... São Carlos: Embrapa Instrumentação; Campo Grande: Embrapa Gado de Corte; Juiz de Fora: Embrapa Gado de Leite, 2014. p. 516-520. Editores: Maria Alice Martins, Humberto de Mello Brandão, Marlene de Barros Coelho, Daniel Souza Corrêa, Caue Ribeiro, Luiz Henrique Capparelli Mattoso.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Instrumentação; Embrapa Semiárido. |
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12. | | BRITTO, D. de; MOURA, M. R. de; AOUADA, F. A.; PINOLA, F. G.; LUNDSTEDT, L. M.; ASSIS, O. B. G.; MATTOSO, L. H. C. Nanopartículas de trimetil quitosana. II-Perfil de liberação controlada de vitaminas hidrossolúveis. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 8, 2014, Juiz de fora. Anais... São Carlos: Embrapa Instrumentação; Campo Grande: Embrapa Gado de Corte; Juiz de Fora: Embrapa Gado de Leite, 2014. p. 520-524. Editores: Maria Alice Martins, Humberto de Mello Brandão, Marlene de Barros Coelho, Daniel Souza Corrêa, Caue Ribeiro, Luiz Henrique Capparelli Mattoso.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Instrumentação; Embrapa Semiárido. |
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13. | | FERREIRA, L. M. B.; ALONSO, J. D.; KIILL, C. P.; FERREIRA, N. N.; BUZZÁ, H. H.; GODOI, D. R. M. de; BRITTO, D. de; ASSIS, O. B. G. de; SERAPHIM, T. V.; BORGES, J. C.; GREMIÃO, M. P. D. Exploiting supramolecular interactions to produce bevacizumab-loaded nanoparticles for potential mucosal delivery. European Polymer Journal, v. 103, p. 238-250, jun. 2018. 238-250Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Instrumentação; Embrapa Semiárido. |
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Registros recuperados : 13 | |
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