| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Florestas. Para informações adicionais entre em contato com cnpf.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Florestas. |
|
Data corrente: |
15/08/2025 |
|
Data da última atualização: |
20/08/2025 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
GAGOSIAN, V. S.; CLARO, F. C.; SCHWARZER, A. C. de A.; CRUZ, J. V.; THÁ, E. L.; TRINDADE, E. da S.; MAGALHAES, W. L. E.; PESTANA, C. B.; LEME, D. M. |
|
Afiliação: |
VIVIANA S.C. GAGOSIAN, UNIVERSIDADE FEDERAL DO PARANA; FRANCINE CECCON CLARO, UNIVERSIDADE FEDERAL DO PARANA; ANA CAROLINA DE A.P. SCHWARZER, UNIVERSIDADE FEDERAL DO PARANA; JULIANA VARELLA CRUZ, UNIVERSIDADE FEDERAL DO PARANA; EMANOELA L. THÁ, UNIVERSIDADE FEDERAL DO PARANA; EDVALDO DA S. TRINDADE, UNIVERSIDADE FEDERAL DO PARANA; WASHINGTON LUIZ ESTEVES MAGALHAES, CNPF; CYNTHIA B. PESTANA, UNIVERSIDADE FEDERAL DO PARANA; DANIELA M. LEME, UNIVERSIDADE FEDERAL DO PARANA. |
|
Título: |
The potential use of kraft lignins as natural ingredients for cosmetics: Evaluating their photoprotective activity and skin irritation potential. |
|
Ano de publicação: |
2022 |
|
Fonte/Imprenta: |
International Journal of Biological Macromolecules, v. 222, Part B, p. 2535-2544, 2022. |
|
ISSN: |
0141-8130 |
|
DOI: |
https://doi.org/10.1016/j.ijbiomac.2022.10.037 |
|
Idioma: |
Inglês |
|
Conteúdo: |
The cosmetics market has recently undergone changes as consumers increasingly seek sustainable products. In this context, agro-derived lignins have the potential for cosmetics applications. Thus, this study investigated the photoprotective activity and skin irritation potential (OECD TG 439 with SkinVitro-RHE, an in-house reconstructed human epidermis (RHE) model) of a kraft lignin (LE) and two LE-derived lignins modified by enzymatic reactions to achieve higher molecular weight (Mw) (R1: intermediate Mw and E60: highest Mw). Results showed that LE and R1 lignins present adequate photoprotective activity with averages Sun Protection Factor (SPF) of 33.8 ± 0.02 and 22.7 ± 0.04, respectively. The E60 also present adequate SPF (22.4 ± 0.2); however, due to its poor solubility, this lignin has potential application as a physical filter. In terms of safety, these lignins did not cause skin irritation or cellular and structural damage to the epidermis. Additionally, using an analysis based on the autofluorescence feature of lignin, no sign of the tested lignins was found in exposed RHE models, indicating that these three lignins did not penetrate the skin. Altogether, the results indicate a promising application of kraft lignins for sunscreen products regarding safer alternatives and product sustainability. Also, the SkinVitro-RHE showed to be a good model for evaluating the skin irritation potential of substances, including natural cosmetic ingredients. |
|
Palavras-Chave: |
Atividade fotoprotetora; Cosmético; Epiderme humana reconstruída; Kraft lignin; Lignina Kraft; Photoprotective activity; Produto sustentável; Reconstructed human epidermis; Sustainable product. |
|
Thesagro: |
Ingrediente. |
|
Thesaurus Nal: |
Ingredients; Lignin; Skin irritation. |
|
Categoria do assunto: |
K Ciência Florestal e Produtos de Origem Vegetal |
|
Marc: |
LEADER 02747naa a2200397 a 4500
001 2178068
005 2025-08-20
008 2022 bl uuuu u00u1 u #d
022 $a0141-8130
024 7 $ahttps://doi.org/10.1016/j.ijbiomac.2022.10.037$2DOI
100 1 $aGAGOSIAN, V. S.
245 $aThe potential use of kraft lignins as natural ingredients for cosmetics$bEvaluating their photoprotective activity and skin irritation potential.$h[electronic resource]
260 $c2022
520 $aThe cosmetics market has recently undergone changes as consumers increasingly seek sustainable products. In this context, agro-derived lignins have the potential for cosmetics applications. Thus, this study investigated the photoprotective activity and skin irritation potential (OECD TG 439 with SkinVitro-RHE, an in-house reconstructed human epidermis (RHE) model) of a kraft lignin (LE) and two LE-derived lignins modified by enzymatic reactions to achieve higher molecular weight (Mw) (R1: intermediate Mw and E60: highest Mw). Results showed that LE and R1 lignins present adequate photoprotective activity with averages Sun Protection Factor (SPF) of 33.8 ± 0.02 and 22.7 ± 0.04, respectively. The E60 also present adequate SPF (22.4 ± 0.2); however, due to its poor solubility, this lignin has potential application as a physical filter. In terms of safety, these lignins did not cause skin irritation or cellular and structural damage to the epidermis. Additionally, using an analysis based on the autofluorescence feature of lignin, no sign of the tested lignins was found in exposed RHE models, indicating that these three lignins did not penetrate the skin. Altogether, the results indicate a promising application of kraft lignins for sunscreen products regarding safer alternatives and product sustainability. Also, the SkinVitro-RHE showed to be a good model for evaluating the skin irritation potential of substances, including natural cosmetic ingredients.
650 $aIngredients
650 $aLignin
650 $aSkin irritation
650 $aIngrediente
653 $aAtividade fotoprotetora
653 $aCosmético
653 $aEpiderme humana reconstruída
653 $aKraft lignin
653 $aLignina Kraft
653 $aPhotoprotective activity
653 $aProduto sustentável
653 $aReconstructed human epidermis
653 $aSustainable product
700 1 $aCLARO, F. C.
700 1 $aSCHWARZER, A. C. de A.
700 1 $aCRUZ, J. V.
700 1 $aTHÁ, E. L.
700 1 $aTRINDADE, E. da S.
700 1 $aMAGALHAES, W. L. E.
700 1 $aPESTANA, C. B.
700 1 $aLEME, D. M.
773 $tInternational Journal of Biological Macromolecules$gv. 222, Part B, p. 2535-2544, 2022.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Florestas (CNPF) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 1 | |
| 1. |  | COELHO, T. L. S.; SILVA, D. S. N.; SOUZA FILHO, L. B. DE; ROCHA, J. M.; MARCANO DE HIGUERA, J.; SÁ, I. P. DE; GAMELA, R. R.; NOGUEIRA, A. R. de A.; LOPES JÚNIOR, C. A.; VIEIRA, E. C. High enhancement of macro and micronutrients quantification in Cajuína by ICP OES using ultrasound and multivariate analysis. Food Chemistry Advances, v. 2, 2023. 8 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
|    |
| Registros recuperados : 1 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
