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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
14/10/2024 |
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Data da última atualização: |
03/01/2025 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
MENDONCA, L. C.; CARVALHO, W. A.; CAMPOS, M. M.; SOUZA, G. N. de; OLIVEIRA, S. A. de; MERINGHE, G. K. F.; NEGRÃO, J. A. |
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Afiliação: |
LETICIA CALDAS MENDONCA, CNPGL; WANESSA ARAUJO CARVALHO, CNPGL; MARIANA MAGALHAES CAMPOS, CNPGL; GUILHERME NUNES DE SOUZA, CNPGL; UNIVERSIDADE DE SÃO PAULO; UNIVERSIDADE DE SÃO PAULO; UNIVERSIDADE DE SÃO PAULO. |
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Título: |
Heat stress affects milk yield, milk quality, and gene expression profiles in mammary cells of Girolando cows. |
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Ano de publicação: |
2025 |
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Fonte/Imprenta: |
Journal of Dairy Science, v. 108, n. 1, p. 1039–1049, 2025. |
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DOI: |
https://doi.org/10.3168/jds.2024-25498 |
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Idioma: |
Inglês |
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Conteúdo: |
Heat stress during lactation affects the physiological responses, hormonal release, health, and productivity of dairy cows. However, the adverse effects of heat stress on milk synthesis, immune response, and cellular apoptosis in mammary cells remains unknown in Bos indicus cows. This study aimed to understand the relationship between milk yield, milk quality, and the expression of genes related to milk synthesis, cell apoptosis, and immune response in mammary cells of Girolando cows. A total of 24 Girolando cows (3/4 Holstein and 1/4 Gir) were subjected to control (CT; with a temperature-humidity index ranging from 60 to 74, n = 12) or heat stress treatments (HS; with a temperature-humidity index ranging from 60 to 85, n = 12), from 111 to 120 d of lactation. Heat stress significantly increased the expression of heat shock proteins (HSPD1 and HSPD90AA1), insulin receptors (INSR), and prolactin receptor (PRLRsf) genes, and decreased the expression of glucocorticoid receptor (NR3C1) gene in mammary cells of the HS cows when compared with the CT cows. The HS cows exhibited significantly higher vaginal temperatures and cortisol release compared with the CT cows. Moreover, the HS cows had significantly lower DMI and milk yield than CT cows. Although, HS cows showed higher percentage of lymphocytes in milk when compared with that from CT cows. We found no effect of heat stress on other leukocyte counts, somatic cell counts, bacterial counts in milk, or milk composition. Finally, this study demonstrated that Girolando cows are susceptible to heat stress, which decreases milk yield and affects the expression of genes linked to milk synthesis in the mammary cells. Key words: Girolando, heat stress, milk yield, mammary cells, gene expression. MenosHeat stress during lactation affects the physiological responses, hormonal release, health, and productivity of dairy cows. However, the adverse effects of heat stress on milk synthesis, immune response, and cellular apoptosis in mammary cells remains unknown in Bos indicus cows. This study aimed to understand the relationship between milk yield, milk quality, and the expression of genes related to milk synthesis, cell apoptosis, and immune response in mammary cells of Girolando cows. A total of 24 Girolando cows (3/4 Holstein and 1/4 Gir) were subjected to control (CT; with a temperature-humidity index ranging from 60 to 74, n = 12) or heat stress treatments (HS; with a temperature-humidity index ranging from 60 to 85, n = 12), from 111 to 120 d of lactation. Heat stress significantly increased the expression of heat shock proteins (HSPD1 and HSPD90AA1), insulin receptors (INSR), and prolactin receptor (PRLRsf) genes, and decreased the expression of glucocorticoid receptor (NR3C1) gene in mammary cells of the HS cows when compared with the CT cows. The HS cows exhibited significantly higher vaginal temperatures and cortisol release compared with the CT cows. Moreover, the HS cows had significantly lower DMI and milk yield than CT cows. Although, HS cows showed higher percentage of lymphocytes in milk when compared with that from CT cows. We found no effect of heat stress on other leukocyte counts, somatic cell counts, bacterial counts in milk, or milk composition. Finally, ... Mostrar Tudo |
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Palavras-Chave: |
Estresse térmico; Expressão genética. |
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Thesagro: |
Bovino; Produção Leiteira. |
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Thesaurus Nal: |
Girolando. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02594naa a2200265 a 4500
001 2168043
005 2025-01-03
008 2025 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.3168/jds.2024-25498$2DOI
100 1 $aMENDONCA, L. C.
245 $aHeat stress affects milk yield, milk quality, and gene expression profiles in mammary cells of Girolando cows.$h[electronic resource]
260 $c2025
520 $aHeat stress during lactation affects the physiological responses, hormonal release, health, and productivity of dairy cows. However, the adverse effects of heat stress on milk synthesis, immune response, and cellular apoptosis in mammary cells remains unknown in Bos indicus cows. This study aimed to understand the relationship between milk yield, milk quality, and the expression of genes related to milk synthesis, cell apoptosis, and immune response in mammary cells of Girolando cows. A total of 24 Girolando cows (3/4 Holstein and 1/4 Gir) were subjected to control (CT; with a temperature-humidity index ranging from 60 to 74, n = 12) or heat stress treatments (HS; with a temperature-humidity index ranging from 60 to 85, n = 12), from 111 to 120 d of lactation. Heat stress significantly increased the expression of heat shock proteins (HSPD1 and HSPD90AA1), insulin receptors (INSR), and prolactin receptor (PRLRsf) genes, and decreased the expression of glucocorticoid receptor (NR3C1) gene in mammary cells of the HS cows when compared with the CT cows. The HS cows exhibited significantly higher vaginal temperatures and cortisol release compared with the CT cows. Moreover, the HS cows had significantly lower DMI and milk yield than CT cows. Although, HS cows showed higher percentage of lymphocytes in milk when compared with that from CT cows. We found no effect of heat stress on other leukocyte counts, somatic cell counts, bacterial counts in milk, or milk composition. Finally, this study demonstrated that Girolando cows are susceptible to heat stress, which decreases milk yield and affects the expression of genes linked to milk synthesis in the mammary cells. Key words: Girolando, heat stress, milk yield, mammary cells, gene expression.
650 $aGirolando
650 $aBovino
650 $aProdução Leiteira
653 $aEstresse térmico
653 $aExpressão genética
700 1 $aCARVALHO, W. A.
700 1 $aCAMPOS, M. M.
700 1 $aSOUZA, G. N. de
700 1 $aOLIVEIRA, S. A. de
700 1 $aMERINGHE, G. K. F.
700 1 $aNEGRÃO, J. A.
773 $tJournal of Dairy Science$gv. 108, n. 1, p. 1039–1049, 2025.
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Embrapa Gado de Leite (CNPGL) |
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| 1. |  | SANTOS, I, M. O. dos; ABE, V. Y.; CARVALHO, K. de; BARAZETTI, A. R.; SIMIONATO, A. S.; PEGA, G. E. de A.; MATIS, S. H.; CANO, B. G.; CELY, M. V. T.; MARCELINO-GUIMARÃES, F. C.; CHRYSSAFIDS, A. L.; ANDRADE, G. Secondary metabolites of Pseudomonas aeruginosa lv strain decrease asian soybean rust severity in experimentally infected plants. Plants, v. 10, n. 8, 1495, 2021. 12 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 3 |
| Biblioteca(s): Embrapa Soja. |
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| 2. | | MURATE, L. S.; OLIVEIRA, A. G. de; HIGASHI, A. Y.; BARAZETTI, A. R.; SIMIONATO, A. S.; SILVA, C. S. da; SIMÕES, G. C.; SANTOS, I. M. O. dos; FERREIRA, M. R.; CELY, M. V. T.; NAVARRO, M. O. P.; FREITAS, V. F. de; NOGUEIRA, M. A.; MELLO, J. C. P. de; LEITE JÚNIOR, R. P.; ANDRADE, G. Activity of secondary bacterial metabolites in the control of citrus canker. Agricultural Sciences, v. 6, n. 3, p. 295-303, Mar. 2015.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 4 |
| Biblioteca(s): Embrapa Soja. |
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