| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
|
Data corrente: |
26/04/2000 |
|
Data da última atualização: |
04/08/2023 |
|
Autoria: |
PATERSON, S.; WILSON, K.; PEMBERTON, J. M. |
|
Título: |
Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population (Ovis aries L.). |
|
Ano de publicação: |
1998 |
|
Fonte/Imprenta: |
Proceedings National Academy Science, v. 95, n. 7, p. 3714-3729, Mar. 1998. |
|
DOI: |
10.1073/pnas.95.7.3714 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: Antagonistic coevolution between hosts and parasites has been proposed as a mechanism maintaining genetic diversity in both host and parasite populations. In particular, the high levels of genetic diversity widely observed at the major histocompatibility complex (MHC) of vertebrate hosts are consistent with the hypothesis of parasite-driven balancing selection acting to maintain MHC genetic diversity. To date, however, empirical evidence in support of this hypothesis, especially from natural populations, has been lacking. A large unmanaged population of Soay sheep (Ovis aries L.) is used to investigate associations between MHC variation, juvenile survival, and parasite resistance. We show in an unmanaged, nonhuman population that allelic variation within the MHC is significantly associated with differences in both juvenile survival and resistance to intestinal nematodes. Certain MHC alleles are associated with low survivorship probabilities and high levels of parasitism or vice versa. We conclude that parasites are likely to play a major role in the maintenance of MHC diversity in this population. |
|
Palavras-Chave: |
Controle; Genetic diversity; Nematodeo gastrintestinal; Ovinos; Selection. |
|
Thesagro: |
Resistência Genética. |
|
Thesaurus Nal: |
Gastrointestinal nematodes; Genetic resistance; Parasites; Parasitology; Sheep. |
|
Categoria do assunto: |
H Saúde e Patologia |
|
Marc: |
LEADER 02051naa a2200289 a 4500
001 1524116
005 2023-08-04
008 1998 bl uuuu u00u1 u #d
024 7 $a10.1073/pnas.95.7.3714$2DOI
100 1 $aPATERSON, S.
245 $aMajor histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population (Ovis aries L.).$h[electronic resource]
260 $c1998
520 $aAbstract: Antagonistic coevolution between hosts and parasites has been proposed as a mechanism maintaining genetic diversity in both host and parasite populations. In particular, the high levels of genetic diversity widely observed at the major histocompatibility complex (MHC) of vertebrate hosts are consistent with the hypothesis of parasite-driven balancing selection acting to maintain MHC genetic diversity. To date, however, empirical evidence in support of this hypothesis, especially from natural populations, has been lacking. A large unmanaged population of Soay sheep (Ovis aries L.) is used to investigate associations between MHC variation, juvenile survival, and parasite resistance. We show in an unmanaged, nonhuman population that allelic variation within the MHC is significantly associated with differences in both juvenile survival and resistance to intestinal nematodes. Certain MHC alleles are associated with low survivorship probabilities and high levels of parasitism or vice versa. We conclude that parasites are likely to play a major role in the maintenance of MHC diversity in this population.
650 $aGastrointestinal nematodes
650 $aGenetic resistance
650 $aParasites
650 $aParasitology
650 $aSheep
650 $aResistência Genética
653 $aControle
653 $aGenetic diversity
653 $aNematodeo gastrintestinal
653 $aOvinos
653 $aSelection
700 1 $aWILSON, K.
700 1 $aPEMBERTON, J. M.
773 $tProceedings National Academy Science$gv. 95, n. 7, p. 3714-3729, Mar. 1998.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 1 | |
| 1. |  | ANGELOTTI, F.; CARVALJO, T. T.; GAVA, C. A. T.; MAGALHÃES, E. E. de; BASTOS, D. C. Controle do míldio da videira (Plasmopara viticola) no Vale do São Francisco. In: SEMINÁRIO BRASILEIRO DE PRODUÇÃO INTEGRADA DE FRUTAS, 11.; SEMINÁRIO SOBRE SISTEMA AGROPECUÁRIO DE PRODUÇÃO INTEGRADA, 3., 2009, Petrolina. Produção integrada: base de sustentabilidade para a agropecuária brasileira. Petrolina: Embrapa Semi-Árido: Valexport, 2009. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Semiárido. |
|    |
| Registros recuperados : 1 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
