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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
05/12/2023 |
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Autoria: |
HUGHES, D. L.; TREACHER, R. J.; HARNESS, E. |
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Título: |
The anthelmintic activity of diamphenethide against immature Fasciola hepatica in goats and the course of experimental infections as demonstrated by plasma enzyme changes. |
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Ano de publicação: |
1974 |
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Fonte/Imprenta: |
Research in Veterinary Science, v. 17, n. 3, p. 302-311, Nov. 1974. |
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DOI: |
https://doi.org/10.1016/S0034-5288(18)33648-8 |
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Idioma: |
Inglês |
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Conteúdo: |
The anthelmintic efficacy of diamphenethide given at 100 mg per kg against one and 3-week-old Fasciola hepatica injections, produced in goats by the administration of 200 cysts was found to be 84% and 97% respectively. Anthelmintic activity could be detected 2 weeks after dosing by a lowering of the sorbitol and glutamate dehydrogenase activity in the plasma compared with control groups. The progressive increase seen in the plasma enzyme activity during the course of infection appeared to be associated with the migration of the living parasite through the liver parenchyma because this increase stopped abruptly and returned to normal when a 3-week-old infection was terminated. The progressive liver damage seen in an infection could be monitored in individual goats by measuring plasma enzyme concentrations. The effect of a more severe infection on the plasma enzyme activity, blood picture, weight gain and faecal egg count was examined by using a group of goats infected with 1000 cysts. |
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Palavras-Chave: |
Controle; Diamphenethide; Drugs effects; Experimental infection; Trematodeos. |
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Thesagro: |
Caprino; Fascíola Hepática; Parasitologia. |
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Thesaurus Nal: |
Anthelmintics; Goats; Parasitology. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01934naa a2200289 a 4500
001 1522570
005 2023-12-05
008 1974 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/S0034-5288(18)33648-8$2DOI
100 1 $aHUGHES, D. L.
245 $aThe anthelmintic activity of diamphenethide against immature Fasciola hepatica in goats and the course of experimental infections as demonstrated by plasma enzyme changes.$h[electronic resource]
260 $c1974
520 $aThe anthelmintic efficacy of diamphenethide given at 100 mg per kg against one and 3-week-old Fasciola hepatica injections, produced in goats by the administration of 200 cysts was found to be 84% and 97% respectively. Anthelmintic activity could be detected 2 weeks after dosing by a lowering of the sorbitol and glutamate dehydrogenase activity in the plasma compared with control groups. The progressive increase seen in the plasma enzyme activity during the course of infection appeared to be associated with the migration of the living parasite through the liver parenchyma because this increase stopped abruptly and returned to normal when a 3-week-old infection was terminated. The progressive liver damage seen in an infection could be monitored in individual goats by measuring plasma enzyme concentrations. The effect of a more severe infection on the plasma enzyme activity, blood picture, weight gain and faecal egg count was examined by using a group of goats infected with 1000 cysts.
650 $aAnthelmintics
650 $aGoats
650 $aParasitology
650 $aCaprino
650 $aFascíola Hepática
650 $aParasitologia
653 $aControle
653 $aDiamphenethide
653 $aDrugs effects
653 $aExperimental infection
653 $aTrematodeos
700 1 $aTREACHER, R. J.
700 1 $aHARNESS, E.
773 $tResearch in Veterinary Science$gv. 17, n. 3, p. 302-311, Nov. 1974.
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| 1. |  | MORAES, W. A.; REIS, R. P.; FONSECA FILHO, H.; TALITANE, I. C.; NORONHA, J. F. de; NEVES, E. M.; FERREIRA NETO, J.; FARIA, J. M. R. Custo de implantacao de seringal cultivado nos estados de Minas Gerais, Espirito Santo e Rio de Janeiro. In: ENCONTRO BRASILEIRO DE ECONOMIA FLORESTAL, 1., 1988, Curitiba. Anais. Curitiba: EMBRAPA-CNPF, 1988. v. 2, p. 335-368.| Biblioteca(s): Embrapa Florestas. |
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