Data/hora: 17/06/2024 03:18:50

Biblioteca(s): 	Embrapa Gado de Corte; Embrapa Gado de Leite; Embrapa Pecuária Sudeste.	
Data corrente: 	19/08/2021	
Data da última atualização: 	29/12/2021	
Autoria: 	VERARDO, L. L.; SILVA, F. F. e; MACHADO, M. A.; PANETTO, J. C. do C.; REIS, D. R. de L.; OTTO, P. I.; REGITANO, L. C. de A.; SILVA, L. O. C. da; EGITO, A. A. do; ALBUQUERQUE, M. do S. M.; ZANELLA, R.; SILVA, M. V. G. B.	
Afiliação: 	LUCAS LIMA VERARDO, Universidade Federal dos Vales do Jequitinhonha e Mucuri; FABYANO FONSECA E SILVA, Universidade Federal de Viçosa; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; DANIELE RIBEIRO DE LIMA REIS FAZA, CNPGL; PAMELA ITAJARA OTTO, Universidade Federal de Santa Maria; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; LUIZ OTAVIO CAMPOS DA SILVA, CNPGC; ANDREA ALVES DO EGITO, CNPGC; MARIA DO SOCORRO MAUÉS ALBUQUERQUE; RICARDO ZANELLA, Universidade de Passo Fundo; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL.	
Título: 	Genome-wide analyses reveal the genetic architecture and candidate genes of indicine, taurine, synthetic crossbreds, and locally adapted cattle in Brazil.	
Ano de publicação: 	2021	
Fonte/Imprenta: 	Frontiers in Genetics, v. 12, article 702822, 2021.	
DOI: 	https://doi.org/10.3389/fgene.2021.702822	
Idioma: 	Inglês	
Conteúdo: 	Cattle population history, breeding systems, and geographic subdivision may be reflected in runs of homozygosity (ROH), effective population size (Ne), and linkage disequilibrium (LD) patterns. Thus, the assessment of this information has become essential to the implementation of genomic selection on purebred and crossbred cattle breeding programs. In this way, we assessed the genotype of 19 cattle breeds raised in Brazil belonging to taurine, indicine, synthetic crossbreds, and Iberian-derived locally adapted ancestries to evaluate the overall LD decay patterns, Ne, ROH, and breed composition. We were able to obtain a general overview of the genomic architecture of cattle breeds currently raised in Brazil and other tropical countries. We found that, among the evaluated breeds, different marker densities should be used to improve the genomic prediction accuracy and power of genome-wide association studies. Breeds showing low Ne values indicate a recent inbreeding, also reflected by the occurrence of longer ROH, which demand special attention in the matting schemes to avoid extensive inbreeding. Candidate genes (e.g., ABCA7, PENK, SPP1, IFNAR1, IFNAR2, SPEF2, PRLR, LRRTM1, and LRRTM4) located in the identified ROH islands were evaluated, highlighting biological processes involved with milk production, behavior, rusticity, and fertility. Furthermore, we were successful in obtaining the breed composition regarding the taurine and indicine composition using single-nucleotide polymorphism (SNP) data.	
Palavras-Chave: 	Rusticidade; Rusticity.	
Thesagro: 	Bovino; Comportamento Animal; Fertilidade Animal; Gado; Genética Animal; Genoma; Produção Leiteira.	
Thesaurus Nal: 	Animal behavior; Animal fertility; Homozygosity; Linkage disequilibrium; Milk production; Population size.	
Categoria do assunto: 	K Ciência Florestal e Produtos de Origem Vegetal	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/225349/1/Genome-wide.pdf	
Registro original: 	Embrapa Gado de Leite (CNPGL)	
Exemplares: 	CNPGL - (25248-1) - UPC - AP - DD -  -  -  - DIS
CNPGC - (17697-1) - UPC - AP - DD -  -  -  - DIS
CPPSE - (25384-1) - UPC - AP - DD - PROCI-2021.00102 - VER - 2021.00118 - DIS