Data/hora: 21/06/2024 14:23:55

Biblioteca(s): | Embrapa Florestas.
Data corrente: | 22/04/2020
Data da última atualização: | 03/05/2024
Autoria: | CLARO, F. C.; JORDÃO, C.; VIVEIROS, B. M. de; ISAKA, L. J. E.; VILLANOVA JUNIOR, J. A.; MAGALHAES, W. L. E.
Afiliação: | Francine Ceccon Claro, Doutoranda da UFPR; Caroline Jordão, Mestranda da UFPR; Bruno Massa de Viveiros, PUC-PR; Luciano Jose ?Eigio Isaka, PUC-PR; José Ademar Villanova Junior, PUC-PR; WASHINGTON LUIZ ESTEVES MAGALHAES, CNPF.
Título: | Low cost membrane of wood nanocellulose obtained by mechanical defibrillation for potential applications as wound dressing.
Ano de publicação: | 2020
Fonte/Imprenta: | Cellulose, v. 7, p. 10765-10779, 2020.
DOI: | https://doi.org/10.1007/s10570-020-03129-2
Idioma: | Inglês
Conteúdo: | Large wounds are characterized by clini-cal and surgical challenges, requiring numeroussearches on demand for inexpensive biocompatiblematerials that produce the best quality of cutaneoushealing. Cellulose is a biopolymer of greatest abun-dance, good biocompatibility and wide applicationdue to its chemical and physical properties. This studywas aimed to develop and characterize low costmembranes of wood cellulose nanofibrils for potentialapplication as a wound dressing in comparison to acommercial porous regenerating membrane. An inex-pensive mechanical method was used to defibrillatecellulose, and later the membranes were obtained fromthe nanofibrils by filtering and drying under mildpressure. The techniques employed for characteriza-tion included scanning electron microscopy, physicaltesting, application in vivo and cost-effectivenessanalysis. The membranes presented promising phys-ical properties for application as cutaneous dressing,with characteristic translucency allowing the evalua-tion of the wound without the need of removal andexchange of the dressing. Wood nanocellulose dress-ing seems to be promising for wound care since itpresented good adhesion to the moist wound surfacesthus promoting the most efficient repitialization in thefirst 4 days. No allergic reaction or inflammatoryresponse to wood nanocellulose dressings wasobserved. The wood nanocellulose membranes standout as a potential wound dressing, as it shows similarefficacy of bacterial cellulose dressing. Besides theefficacy, the membrane developed in this studypresents a simpler, faster and cheaper manufacturingprocess, which may reduce the production cost by99%
Palavras-Chave: | Biocompatible; Cost-effectiveness; Healing; Nanofiber; Nanofibra; Nanomaterial.
Thesaurus Nal: | Nanomaterials.
Categoria do assunto: | X Pesquisa, Tecnologia e Engenharia
Registro original: | Embrapa Florestas (CNPF)
Exemplares: | CNPF - (57291-1) - UPC - AP - DD -  -  -  - DIS