01906nam a2200241 a 450000100080000000500110000800800410001910000220006024501300008226001630021230000130037552010930038865000180148165000150149965000170151465300250153165300140155665300080157065300250157870000200160370000220162370000190164519631292026-06-24 2013 bl uuuu u00u1 u #d1 aNICIURA, S. C. M. aGenetics of Haemonchus contortus and risk factors for sheep flocks related to anthelmintic resistance.h[electronic resource] aIn: ANNUAL MEETING BRAZILIAN SOCIETY OF ANIMAL SCIENCE, 50., 2013, Campinas. The integration of Knowledge in animal production - Palestra. Campinas: SBZc2013 c1 CD-ROM aDespite the increasing economic importance of the small ruminant production, parasite resistance continues to stand out as the main constraint to this activity. Haemonchus contortus, the most prevalent and pathogenic nematode in tropical areas, is responsible for economic losses and health problems. The purpose of this review is to present the current knowledge about H. contortus genetics, anthelmintic resistance and management practices in sheep flocks associated with parasite resistance. We present the main results of our team obtained in sheep flocks from São Paulo state, Brazil, in recent years regarding efficiency assessment of five anthelmintics by the fecal egg count reduction test (FECRT); genotyping of two genes related to anthelmintic resistance (βtubulin and P-glycoprotein); and risk factors in management practices associated with anthelmintic resistance. We aim to provide useful information to improve control, maintain the effectiveness of chemical groups, slow the emergence of anthelmintic resistance in sheep and help farmers deal with parasitic resistance. aAnthelmintics aHaemonchus aRisk factors aManagement practices aMultidrug aPCR aResistance nematodes1 aMELLO, S. S. de1 aVERÍSSIMO, C. J.1 aMOLENTO, M. B.