03027naa a2200265 a 450000100080000000500110000800800410001910000180006024500820007826000090016050000310016952022940020065000100249465000120250465000160251665300170253270000200254970000190256970000200258870000130260870000190262170000260264070000160266677300790268219539202024-01-18       2008    bl uuuu     u00u1 u    #d1 aBENESI, F. J.  aRelato de casobtuberculose em caprino (Capra hircus).h[electronic resource]  c2008  aComunicação científica.  aResumo: Uma cabra da raça Saanem, com 3 anos, foi atendida no Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo, com histórico de emagrecimento progressivo, com doença respiratória não responsiva a antibioticoterapia convencional. O animal apresentava perda de peso, aumento de linfonodo submandibular esquerdo e sintomas de broncopneumonia. Tendo sido considerado positivo no teste cervical comparativo foi sacrificado e à necropsia foram observadas lesões sugestivas de tuberculose nos linfonodos submandibulares e mesentéricos, pulmão e baço. Nos exames laboratoriais houve crescimento, aos 32 dias, de bacilos álcool-ácido resistentes (BAAR), no meio de cultura de Stonebrink, e a estirpe isolada foi identificada no PCR como sendo Mycobacterium bovis. A pesquisa de Corynebacterium sp. foi negativa. Na histopatologia, as lesões examinadas apresentavam características dos granulomas típicos. Usandose coloração para BAAR foi possível observação de bacilos no centro de um granuloma, sugestivo de Mycobacterium spp. Casos de tuberculose em caprinos têm sido considerados raros no Brasil [Case report: tuberculosis in a goat (Capra hircus)]. Abstract: A 3-year-old Saanen-breed was examined at the Veterinary Hospital of the College of Veterinary Medicine and Animal Husbandry of the University of São Paulo, with a history of progressive emaciation and respiratory disease which did not respond to conventional antibiotic therapy. The animal was underweight, had swelling of the left submandibular lymph node and signs of bronchopneumonia. As it was reactor for comparative cervical test, the goat was slaughtered and at necropsy tuberculosis-like lesions were found in its submandibular and mesenteric lymph nodes, lungs and spleen. Acid-fast bacilli growth occurred within 32 days in Stonebrink media culture and the isolate was identified by PCR as M. bovis. Diagnostic test for Corynebacterium sp. was negative. Histopathologic examination showed characteristics of tuberculosis granulomas. When the acid-fast stain was employed in lesions smears, it was possible to observe bacilli in the middle of a granuloma, suggesting Mycobacterium spp. Tuberculosis cases in goats have been considered rare in Brazil  aCabra  aCaprino  aTuberculose  aRaça Saanen1 aPINHEIRO, S. R.1 aMAIORKA, P. C.1 aSAKAMOTO, S. M.1 aROXO, E.1 aBENITES, N. R.1 aBIRGEL JÚNIOR, E. H.1 aGREGORY, L.  tArquivos do Instituto Biológicogv. 75, n. 2, p. 217-220, abr./jun. 2008.