01401nam a2200193 a 450000100080000000500110000800800410001910000180006024501700007826001140024850001630036252005600052565000220108565300200110770000220112770000200114970000210116970000170119019526302013-03-11 2012 bl uuuu u00u1 u #d1 aALEXANDRE, P. aMolecular characterization of constitutive androstane receptor (CAR) and its association with feed efficiency of Nellore (Bos indicus) cattle.h[electronic resource] aJournal of Animal Science v.90, (Supplement 3/J); Journal of Dairy Science, v.95, (Supplement 2), p.524c2012 aEdição dos trabalhos do: ADSA-PSA-AMPA-ASAS-CSAS-WSASAS JOINT ANNUAL MEETING, 2012, Phoenix-AR. Breeding and Genetics: Molecular Biology and Genomics. W68. aThe constitutive androstane receptor (CAR) was initially characterized as a key regulator of xenobiotic metabolism. CAR has also been implicated in various physiological pathways such as energy metabolism and homeostasis of lipids, triglycerides, cholesterol and other endogenous hydrophobic molecules. Here, our focus was to detect genetic polymorphisms (SNP) of CAR of Nellore beef cattle, predict their functional role and associate them to residual feed intake (RFI) and residual body weight gain (RIG), a recently proposed measure of feed efficiency. aNutrição Animal aBovino de corte1 aSANTANA, M. H. A.1 aGOMES, R. da C.1 aFERRAZ, J. B. S.1 aFUKUMASU, H.