01894naa a2200265 a 450000100080000000500110000800800410001910000190006024501830007926000090026252010700027165000140134165300190135565300160137470000170139070000180140770000180142570000200144370000150146370000180147870000200149670000160151670000180153277300780155019488742015-02-19       2012    bl uuuu     u00u1 u    #d1 aANGELIS, S. de  aCo-culture of microalgae, cyanobacteria, and macromycetes for exopolysaccharides productionbprocess preliminary optimization and partial characterization.h[electronic resource]  c2012  aIn this study, the biomass and exopolysaccharides (EPS) production in co-cultures of microalgae/cyanobacteria and macromycetes was evaluated as a technology for producing new polysaccharides for medical and/or industrial application. Based on biomass and EPS productivity of monocultures, two algae and two fungi were selected and cultured in different co-culture arrangements. The hydrosoluble EPS fractions from mono- and cocultures were characterized by ¹³C NMR spectroscopy and gas chromatography coupled to mass spectrometry and compared. It was found that co-cultures resulted in the production of an EPS different from those produced by monocultures, showing fungal predominance with microalgal/cyanobacterial traces. Co-cultures conditions were screened (temperature, agitation speed, fungal and microalgae inoculation rate, initial pH, illumination rate, and glucose concentration) in order to achieve maximum biomass and EPS production, resulting in an increase of 33 and 61% in exopolysaccharides and biomass productions, respectively (patent pending).  aMicroalga  aCianobactéria  aMacromiceto1 aNOVAK, A. C.1 aSYDNEY, E. B.1 aSOCCOL, V. T.1 aCARVALHO, J. C.1 aPANDEY, A.1 aNOSEDA, M. D.1 aTHOLOZAN, J. L.1 aLORQUIN, J.1 aSOCCOL, C. R.  tApplied Biochemistry and Biotechnologygv. 167, n. 5, p. 1092-1106, 2012.