01320nam a2200241 a 450000100080000000500110000800800410001910000220006024501760008226002200025830000190047850000160049752003990051365000190091265000130093165000140094465300350095870000180099370000170101170000150102870000190104370000160106219434812020-01-08       2012    bl uuuu     u00u1 u    #d1 aNESHICH, I. A. P.  aSize mattersbsurface hydrophobicity index (SHI) describes the impact of the size of interface area on oligomerization driven by hydrophobic effect.h[electronic resource]  aIn: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY; STRUCTURAL BIOINFORMATICS AND COMPUTATIONAL BIOPHYSICS MEETING, 8., 2012, Long Beach, California. Abstracts... California: ISMBc2012  aNão paginado.  a3Dsig 2012.  aWe present an extensive study of protein-protein interfaces in a non-redundant dataset (DS95) containing 6.931 PDB chains which highlights the relationship between hydrophobic effect and oligomerization of proteins by using a newly defined Surface Hydrophobicity Index (SHI). We found that 92% of all DS95 chains have their interface more hydrophobic than the rest of a solvent-exposed surface.  aHydrophobicity  aProteins  aProteína  aHidrofobicidade de superfície1 aMORAES, F. de1 aSALIM, J. A.1 aMAZONI, I.1 aJARDINE, J. G.1 aNESHICH, G.