01696naa a2200277 a 450000100080000000500110000800800410001902400400006010000240010024500730012426000090019752009160020665000170112265000120113965000200115165300210117170000230119270000210121570000180123670000180125470000190127270000200129170000200131170000170133177300700134819028052012-11-30       2011    bl uuuu     u00u1 u    #d7 a10.1016/j.biortech.2011.08.1072DOI1 aMELLINGER-SILVA, C.  aIsolation of a gastroprotective arabinoxylan from sugarcane bagasse.  c2011  aAfter industrial processing, one-third of sugarcane culms is converted into residual bagasse. The xylanrich hemicellulose components of the bagasse were extracted with hot aqueous alkali (AX-CRUDE). Approximately 82% of the extracted hemicelluloses was precipitated with ethanol (AX-PET). Both AXCRUDE and AX-PET contained an arabinoxylan as confirmed by 13C NMR and methylation analysis. Fraction AX-PET was fed to female Wistar rats with ethanol-induced gastric lesions. Oral administrations of 30, 100, and 300 mg/kg reduced the gastric lesion area by over 50%, and replenished ethanol-induced depletion of glutathione. The polysaccharide also increased mucus production by over 70%, indicating its cytoprotective action on experimentally induced gastric ulcers. These findings are significant, since a biologically active compound can be extracted in high yields from an abundant, readily available residue.  aArabinoxylan  aBagaço  aPolissacarídeo  aCana-de-açúcar1 aSIMAS-TOSIN, F. F.1 aSCHIAVINI, D. N.1 aWERNER, M. F.1 aBAGGIO, C. H.1 aPEREIRA, I. T.1 aSILVA, L. M. da1 aGORIN, P. A. J.1 aIACOMINI, M.  tBioresource Technologygv. 102, n. 22, p. 10524-10528, Nov. 2011.