02315naa a2200301 a 450000100080000000500110000800800410001902400540006010000180011424501530013226000090028552013930029465000150168765000150170265000100171765000230172765000200175065000200177065000150179065300170180565300180182265300180184070000240185870000170188270000230189970000230192277300680194518985872022-07-25       2011    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.vetpar.2011.07.0012DOI1 aKATIKI, L. M.  aAnthelmintic activity of Cymbopogon martinii, Cymbopogon schoenanthus and Mentha piperita essential oils evaluated in four different in vitro tests.  c2011  aAnthelmintic resistance is a worldwide concern in small ruminant industry and new plant-derived compounds are being studied for their potential use against gastrointestinal nematodes. Mentha piperita, Cymbopogon martinii and Cymbopogon schoenanthus essential oils were evaluated against developmental stages of trichostrongylids from sheep naturally infected (95% Haemonchus contortus and 5% Trichostrogylus spp.) through the egg hatch assay (EHA), larval development assay (LDA), larval feeding inhibition assay (LFIA), and the larval exsheathment assay (LEA). The major constituent of the essential oils, quantified by gas chromatography for M. piperita oil was menthol (42.5%), while for C. martinii and C. schoenanthus the main component was geraniol (81.4% and 62.5%, respectively). In all in vitro tests C. schoenanthus essential oil had the best activity against ovine trichostrongylids followed by C. martini, while M. piperita presented the least activity. Cymbopogon schoenanthus essential oil had LC50 value of 0.045 mg/ml in EHA, 0.063 mg/ml in LDA, 0.009 mg/ml in LFIA, and 24.66 mg/ml in LEA. The anthelmintic activity of essential oils followed the same pattern in all in vitro tests, suggesting C. schoenanthus essential oil could be an interesting candidate for nematode control, although in vivo studies are necessary to validate the anthelmintic properties of this oil.  aCymbopogon  aHaemonchus  aSheep  aCymbopogon martini  aMentha piperita  aÓleo essencial  aPalma rosa  aCapim-limão  aEssential oil  aIn vitro test1 aCHAGAS, A. C. de S.1 aBIZZO, H. R.1 aFERREIRA, J. F. S.1 aAMARANTE, A. F. T.  tVeterinary Parasitologygv. 183, n. 1-2, p. 103-108, dec. 2011.