02323nam a2200277 a 450000100080000000500110000800800410001910000190006024501030007926001900018250000800037252013250045265000220177765000140179965000230181365300270183665300240186370000160188770000220190370000240192570000260194970000180197570000160199370000170200970000190202610087532024-02-27       2005    bl uuuu     u00u1 u    #d1 aJARDINE, J. G.  aMolecular modeling of the protein twitching motility of Xylella fastidiosa.h[electronic resource]  aIn: X-MEETING; INTERNATIONAL CONFERENCE OF THE AB3C, 1., 2005, Caxambu. [Proceedings...]. [S.l.]: Associação Brasileira de Bioinformática e Biologia Computacional, 2005. p. 99.c2005  aNa publicação: Stanley R. M. Oliveira. X-meeting 2005. Presented Posters.  aIn Brazil, citricuture suffers from serious phytopathologic problems that compromise the orange production. For instance, Citrus ariegated Chiorosis (CVC), a disease also known as "amarelinho", caused by Xylella fastidiosa a slow growing gram-negative bacterium that dwells plant xylem and compromises fruit production, among other vegetables. A laboratory consortium in Sao Paulo, Brazil, has published the X. fastidiosa genome, lineage 9a5c, revealing 2.679.305 pairs of bases in the main chromosome and other two plasmids: one with 51.158 and the other with 1.285 pairs of bases. In the total, 2.905 genes were identified. The proteome project of X. fastidiosa revealed over than 800 expressed proteins and identified 112 proteins, some of them potentially involved in the pathogenic processes of this bacterium in citrus. The goal of this research was to develop preliminary studies regarding the tridimensional structure of the protein identified by the proteome PilT, a product of XF1633 gene. Such a protein is associated with adhesion systems and it is a fimbria of type IV, which is supposed to be responsible for the setting of the bacterium in the vascular system of the plant, through its model constructed by homology modeling with the crystallographic structure of a protein of a supposed Víbrio cholerae.  aProtein structure  aProteína  aXylella fastidiosa  aEstrutura de proteína  aModelagem molecular1 aNESHICH, G.1 aFALCÃO, P. R. K.1 aYAMAGISHI, M. E. B.1 aOLIVEIRA, S. R. de M.1 aMARANGONI, S.1 aMARTINS, D.1 aWINCK, F. V.1 aNOVELLO, J. C.