03568naa a2200577 a 450000100080000000500110000800800410001902400510006010000200011124501540013126000090028552018840029465000170217865000130219565300540220865300160226270000150227870000160229370000140230970000220232370000300234570000250237570000180240070000200241870000180243870000210245670000170247770000190249470000230251370000160253670000160255270000170256870000230258570000210260870000230262970000140265270000210266670000220268770000130270970000210272270000170274370000270276070000180278770000160280570000170282170000250283870000140286370000230287770000210290077300690292121604022024-01-24       2024    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1177/026119292312183782DOI1 aAVILA, R. I. de  aBrazilian National Network of Alternative Methods (RENAMA) 10th anniversarybmeeting of the associated laboratories, may 2022.h[electronic resource]  c2024  aThe Brazilian National Network of Alternative Methods (RENAMA), which is linked to the Ministry of Science, Technology and Innovation, is currently comprised of 51 laboratories from CROs, academia, industry and government. RENAMA’s aim is to develop and validate new approach methodologies (NAMs), as well as train researchers and disseminate information on their use — thus reducing Brazilian, and consequently Latin American, dependence on external technology. Moreover, it promotes the adoption of NAMs by educators and trained researchers, as well as the implementation of good laboratory practice (GLP) and the use of certified products. The RENAMA network started its activities in 2012, and was originally comprised of three central laboratories — the National Institute of Metrology, Quality and Technology (INMETRO); the National Institute of Quality Control in Health (INCQS); and the National Brazilian Biosciences Laboratory (LNBio) — and ten associated laboratories. In 2022, RENAMA celebrated its 10th anniversary, a milestone commemorated by the organisation of a meeting attended by different stakeholders, including the RENAMA-associated laboratories, academia, non-governmental organisations and industry. Ninety-six participants attended the meeting, held on 26 May 2022 in Balneario Cambori ´ u, SC, Brazil, as part of the programme of the XXIII Brazilian Congress of Toxicology 2022. Signi ´ ficant moments of the RENAMA were remembered, and new goals and discussion themes were established. The lectures highlighted recent innovations in the toxicological sciences that have translated into the assessment of consumer product safety through the use of human-relevant NAMs instead of the use of existing animal-based approaches. The challenges and opportunities in accepting such practices for regulatory purposes were also presented and discussed.  aLaboratório  aPesquisa  aRede Nacional Brasileira de Métodos Alternativos  aValidação1 aFENTEM, j.1 aVILLELA, I.1 aSOMLO, D.1 aALMEIDA, A. M. F.1 aMENDES-GIANNINI, M. J. S.1 aCANAVEZ, A. D. P. M.1 aBOSQUETTI, B.1 aCATARINO, C. M.1 aSCHUCK, D. C.1 aVALADARES, B. N.1 aFACCHINI, G.1 aMARIGLIANI, B.1 aFIGUEIRA, A. C. M.1 aHICKSON, R.1 aLEME, D. M.1 aTAGLIATI, C.1 aSOUZA, L. C. R. de1 aENGLER, S. S. M.1 aCORDEIRO, L. R. G.1 aKOEPP, J.1 aGRANJEIRO, J. M.1 aBRANDAO, H. de M.1 aMUNK, M.1 aMATTOS, K. A. de1 aPEDRALLI, B.1 aRODRIGUES, M. M. S. F.1 aSTIVAL, A. C.1 aANDRADE, J.1 aBRITO, L. B.1 aSANTOS, T. R. M. dos1 aLEITE, J.1 aSILVA, A. C. G. da1 aVALADARES, M. C.  tAlternatives to Laboratory Animalsgv. 52, n. 1, p. 60-68, 2024.