02395naa a2200349 a 450000100080000000500110000800800410001902200140006002400470007410000220012124501640014326000090030752013150031665000150163165000280164665000330167465000170170765000130172465300370173765300220177465300170179665300140181365300160182765300280184370000250187170000190189670000220191570000200193770000220195770000220197977300440200121523532023-03-14       2022    bl uuuu     u00u1 u    #d  a2304-81587 ahttps://doi.org/10.3390/foods110304492DOI1 aMASSARIOLI, A. P.  aOptimizing procedures for antioxidant phenolics extraction from skin and kernel of peanuts with contrasting levels of drought tolerance.h[electronic resource]  c2022  aPeanut is an affordable legume known for its nutritional value and phenolic content. The kernel and skin of 14 peanut genotypes contrasting in drought tolerance had their phenolic profiles determined and reactive oxygen species (ROS) scavenging activity evaluated. Firstly, temperature and % EtOH to extract antioxidant phenolic compounds were optimized using response surface methodology (RSM). The optimized extraction conditions, 60 ºC and 35% EtOH for kernels and 40 ºC and 60% EtOH for skins, were further adopted, and phenolic compounds were identified and quantified using high-performance liquid chromatography coupled with electrospray ionizationquadrupole- time of flight-mass spectrometry (HPLC-ESI-QTOF-MS) and high-performance liquid chromatography with photodiode array detector (HPLC-PDA). As a result, phenolic acids and glycosidic/non-glycosidic flavonoids were found. Principal component analysis was conducted, and the pairwise score plot of the skin extracts based on individual phenolic compounds showed a trend of genotype clustering based not only on drought tolerance but also on botanical type of germplasm. Therefore, our results demonstrate the status quo for antioxidant phenolic compounds of peanut genotypes contrasting in drought tolerance grown under natural field conditions.  aFlavonoids  aReactive oxygen species  aResponse surface methodology  aWater stress  aAmendoim  aEspécies reagentes ao oxigênio  aEstresse hídrico  aFlavonóides  aGroundnut  aMetodologia  aSuperfície de resposta1 aSARTORI, A. G. de O.1 aJULIANO, F. F.1 aSANTOS, R. C. dos1 aRAMOS, J. P. C.1 aLIMA, L. M. de L.1 aALENCAR, S. M. de  tFoodsgv. 11, n. 3, 449, p. 2-14, 2022.