02726naa a2200421 a 450000100080000000500110000800800410001902400530006010000130011324501450012626000090027152014710028065000170175165000210176865000160178965000310180565000230183665000180185965300350187765300230191265300210193565300210195665300160197770000200199370000170201370000240203070000190205470000210207370000200209470000190211470000230213370000290215670000190218570000170220470000200222170000210224177300420226221515092024-01-12 2023 bl uuuu u00u1 u #d7 ahttps://doi.org/10.3390/fermentation90201572DOI1 aLIMA, R. aChemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (Plinia jabuticaba) Wine and Derived Extracts.h[electronic resource] c2023 aThe alcoholic fermentation of jabuticaba berries (Plinia spp.) originates from a beverage with an intense taste and aroma, popularly known as jabuticaba wine (JW). In addition, polyphenols transferred from fruit peels to the final product turn this beverage into a promising source of bioactive agents. Here, the chemical profile and antioxidant potential of artisanal JW and derivative extracts were determined. Volatile organic compounds were determined by HS-SPME/GC-MS analysis. The wine was dried by lyophilization and subjected to liquid-liquid partitioning (water: ethyl acetate), resulting in three fractions (JWF1-3). ABTS•+ and DPPH•+ scavenging assays were performed to evaluate the antioxidant capacity. In addition, the extracts’ hematoprotective activity was evaluated against oxidative stress. Finally, the extracts were analyzed by LC-HRMS/MS. HS-SPME/GC-MS analysis highlighted 1,8-cineole as the main compound that contributes to the camphor/mint flavor. JWF2 and JWF3 displayed the highest antioxidant capacity. JWF2 stood out for preventing oxidative damage in red blood cells at 7.8 μg·mL−1 The maximal protection of ascorbic acid occurred at 8.8 μg·mL−1. The LC-HRMS/MS analysis allowed the annotation of seventeen compounds, most of them with recognized antioxidant activity such as anthocyanins, catechins, flavanols, and phenolic acids. The results presented herein reinforce JW as a pleasant beverage with bioactive potential. aFermentation aOxidative stress aPolyphenols aVolatile organic compounds aComposto Orgânico aFermentação aCompostos orgânicos voláteis aEstresse oxidativo aHematoproteção aHematoprotection aPolifenóis1 aSILVA, M. V. T.1 aGOMES, B. A.1 aMACEDO, E. H. B. C.1 aSANTANA, M. N.1 aAMARAL, A. C. F.1 aSILVA, J. R. A.1 aCORRÊA, P. G.1 aGODOY, R. L. de O.1 aSANTIAGO, M. C. P. de A.1 aLEITÃO, S. G.1 aSIMAS, R. C.1 aCARNEIRO, C. S.1 aRODRIGUES, I. A. tFermentationgv. 9, n. 2, e157, 2023.