01559nam a2200205 a 450000100080000000500110000800800410001910000240006024501470008426001300023152008400036165000250120165000130122670000170123970000210125670000180127770000160129570000170131170000250132821459832022-11-04       2022    bl uuuu     u00u1 u    #d1 aMORAIS, I. da S. de  aEffects of Mesterolone in the physiology, welfare and masculinization of the neotropical tambaqui Colossoma macropomum.h[electronic resource]  aIn: CONFERENCIA LATINOAMERICANA SOBRE CULTIVO DE PECES NATIVOS, 7., 2022, Belo Horizonte. Anais... Belo Horizonte: UFMGc2022  aFor Brazilian aquaculture, tambaqui Colossoma macropomum is the main native species. In farming conditions, females can grow up to 50% more than the males, most likely for entering puberty later than males. As tambaqui sex-determination system is XX/XY, there is the possibility to generate monosex population of females by crossing out normal females with neo-males (genetic females -XX displaying male phenotype). The goal of this study was to invert the sex phenotype of female tambaqui using mesterolone, which is a synthetic androgen derivative of dihydrotestosterone. Since in fish the hematological parameters may alter as a result of pollutants or drugs used in aquaculture, we evaluated the welfare of treated fish through biomarkers of liver function, i. e. biochemical parameters and histopathological analysis of the liver.  aColossoma Macropomum  aTambaqui1 aSOUSA, R. G.1 aHASHIMOTO, D. T.1 aAMARAL, A. C.1 aREIS, V. R.1 aBRAMBILA, G.1 aO'SULLIVAN, F. L. A.