02788naa a2200529 a 450000100080000000500110000800800410001902200140006002400440007410000180011824501550013626000090029152012840030065000180158465000250160265000160162765000180164365000220166165000180168365000170170165000110171865000180172970000170174770000130176470000240177770000210180170000190182270000300184170000210187170000170189270000230190970000180193270000210195070000220197170000230199370000190201670000240203570000190205970000180207870000200209670000170211670000220213370000130215570000250216870000280219377300370222121453962022-08-12       2022    bl uuuu     u00u1 u    #d  a2072-66437 ahttps://doi.org/10.3390/nu141225472DOI1 aMARCELINO, G.  aCharacterization of buriti (Mauritia flexuosa) pulp oil and the effect of its supplementation in an In vivo experimental model.h[electronic resource]  c2022  aMauritia flexuosa (buriti) pulp oil contains bioactive substances and lipids that are protective against cardiovascular and inflammatory diseases. We performed physical and chemical analyses to verify its quality and stability. buriti oil was stable according to the Rancimat test, presenting an induction period of 6.6 h. We evaluated the effect of supplementation with crude buriti oil and olive oil on metabolic parameters in 108 Swiss mice for 90 days. We investigated six groups: extra virgin olive oil (EVOO) 1 and 2 (1000 and 2000 mg/kg), buriti oil (BO) 1 and 2 (1000 and 2000 mg/kg), synergic (S) (BO1 + EVOO1), and control (water dose 1000 mg/kg). The animals were euthanized to examine their blood, livers, and fats. The supplementation did not interfere with food consumption, weight gain, and histological alterations in the liver. Group S showed the strongest relationship with the fractions HDL-c and non-HDL-c, indicating a possible cardioprotective effect. Moreover, we observed significantly higher IL-6 levels in the control, EVOO2, and BO1 groups than in the EVOO1 group. Resistin was also significantly higher for the synergic treatment than for the control. We conclude that BO combined with EVOO could be an excellent food supplement for human consumption.  aAnimal models  aAntioxidant activity  aFatty acids  aInterleukin-6  aMauritia flexuosa  aVegetable oil  aAntioxidante  aBuriti  aÓleo Vegetal1 aHIANE, P. A.1 aPOTT, A.1 aFILIÚ, W. F. de O.1 aCAIRES, A. R. L.1 aMICHELS, F. S.1 aMARÓSTICA JÚNIOR, M. R.1 aSANTOS, N. M. S.1 aNUNES, A. A.1 aOLIVEIRA, L. C. S.1 aCORTES, M. R.1 aMALDONADE, I. R.1 aCAVALHEIRO, L. F.1 aNAZÁRIO, C. E. D.1 aSANTANA, L. F.1 aFERNANDES, C. D. P.1 aNEGRÃO, F. J.1 aTATARA, M. B.1 aFARIA, B. B. de1 aASATO, M. A.1 aFREITAS, K. de C.1 aBOGO, D.1 aNASCIMENTO, V. A. do1 aGUIMARÃES, R. de C. A.  tNutrientsgv. 14, e. 2547, 2022.