02301naa a2200337 a 450000100080000000500110000800800410001902400500006010000230011024501700013326000090030352012590031265000130157165000230158465000270160765000140163465000100164865300220165865300130168070000230169370000190171670000260173570000200176170000200178170000250180170000230182670000220184970000200187170000250189177300470191621451172022-09-14       2022    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.3390/agronomy120716902DOI1 aOLIVEIRA, L. C. de  aBioprospecting the antibacterial activity of endophytic fungi from noni (Morinda citrifolia) against bacterial spot of the passion fruit tree.h[electronic resource]  c2022  aBacterial spot, which is the main disease occurring in passion fruit trees, is caused by the bacterium Xanthomonas axonopodis pv. passiflorae, leading to large annual losses in passion fruit crops. This study aims to find extracts and/or bioactive compounds of endophytic fungi of noni (Morinda citrifolia) to treat bacterial spot in passion fruit trees. Nine fungi isolated from a specimen of M. citrifolia from the Brazilian Amazon are studied. The fungus Guignardia mangiferae NF17 shows the best inhibition results and is selected for the isolation of its secondary metabolites by chromatography techniques. The isolated compounds Sydowinol (S1) and Sydowinin A (S2) are identified by nuclear magnetic resonance (NMR). Compounds S1 and S2, as well as the acetonitrile extract from the biomass of G. mangiferae NF17, are tested against four strains of X. axonopodis pv. passiflorae obtained from plants infected by bacterial spot, and which inhibited bacterial growth up to the lowest concentration tested (3.125 μg/mL). This study reports, for the first time, the antibacterial activity against X. axonopodis pv. passiflorae by the compounds Sydowinol and Sydowinin A. Compounds S1 and S2 are reported for the first time for the genus Gignardia.  aAmazonia  aMorinda citrifolia  aXanthomonas axonopodis  aXanthones  aFungo  aFungo endofítico  aXantonas1 aCOSTA, W. C. L. da1 aVINAGRE, V. G.1 aSIQUEIRA, J. E. de S.1 aSILVA, S. da C.1 aSILVA, S. Y. S.1 aMARINHO, A. N. do R.1 aROCHA, D. C. da C.1 aMARINHO, P. S. B.1 aNAKASONE, A. K.1 aMARINHO, A. M. do R.  tAgronomygv. 12, n. 7, Article 1690, 2022.