02958naa a2200301 a 450000100080000000500110000800800410001902400540006010000200011424502140013426000090034852020030035765000110236065000130237165000190238465000180240365000120242165300260243370000220245970000190248170000190250070000200251970000180253970000180255770000200257570000180259577300430261321335412021-08-13       2020    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1371/journal.pone.02384192DOI1 aSILVA, D. C. da  aGrouping crossbred Holstein x Gyr heifers according to different feed efficiency indexes and its effects on energy and nitrogen partitioning, blood metabolic variables and gas exchanges.h[electronic resource]  c2020  aThe objectives of this study were: i) to classify animals into groups of high and low feed efficiency (FE) using three FE indexes (Residual feed intake (RFI), Residual weight gain (RG) and Feed conversion efficiency (FCE)), and ii) to evaluate whether crossbreed Holstein x Gyr heifers divergent for FE indexes exhibit differences in nutrient intake and digestibility, energy partitioning, heat production, methane emissions, nitrogen partitioning and blood parameters. Thirty-five heifers were housed in a tie-stall, received ad libitum TMR (75:25, corn silage: concentrate) and were ranked and classified into high (HE) or low efficiency (LE) for RFI, RG and FCE. The number of animals for each HE group were 13 (&lt 0.5 standard deviation (SD) for RFI, 11 for RG and 11 for FCE (&gt 0.5 SD) and for the LE were 10 (&gt 0.5 SD) for RFI, 11 for RG and 12 for FCE (&lt 0.5 SD). Gas exchanges (O2 consumption, CO2 and CH4 production) in open-circuit respiratory chambers and whole tract digestibility trial was performed. A completely randomized experimental design was used and the data were analyzed by ANOVA and correlation study. High efficiency animals for RFI produced less CO2, consumed less O2 and had lower heat production (HP). Methane production was positively correlated with RFI. High efficiency RG had higher O2 consumption and CO2 production in relation to LE-RG. High efficiency FCE had greater NFC digestibility, higher positive energy balance (EB) and excreted (11.4 g/d) less nitrogen in urine. High efficiency RG and FCE groups emitted less CH4 per kg of weight gain than LE animals. Animals HE for RFI and FCE had lower β-hydroxybutyrate and higher glucose concentrations, respectively. The differences in intake, digestibility, energy and nitrogen partition, CH4 emission, blood metabolic variables and heat production between the HE and LE groups varied according to the efficiency indexes adopted. The HP (kcal/d/BW0.75) was lower for HE animals for RFI and FCE indexes.  aBovino  aGado Gir  aGado Holandês  aGado Mestiço  aNovilho  aEficiência alimentar1 aPEREIRA, L. G. R.1 aLIMA, J. A. M.1 aMACHADO, F. S.1 aFERREIRA, A. L.1 aTOMICH, T. R.1 aCOELHO, S. G.1 aMAURICIO, R. M.1 aCAMPOS, M. M.  tPLoS ONEgv. 15, n. 9, e0238419, 2020.