02507naa a2200505 a 450000100080000000500110000800800410001902400480006010000220010824502070013026000090033750000180034652009800036465000250134465000190136965000130138865000230140165000160142465000150144065000200145565000270147565300270150265300150152965300130154465300270155765300180158465300200160265300270162265300110164965300230166065300220168365300220170565300160172770000180174370000230176170000170178470000220180170000290182370000160185270000200186870000170188870000230190570000230192877300500195121320662021-06-15       2021    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1002/cbdv.2021000542DOI1 aMARTINS, V. de C.  aDetermination of the Phytochemical Composition and Antioxidant Potential of Eugenia copacabanensis and Myrciaria tenella Leaves (Myrtaceae) Using a Saccharomyces cerevisiae Model.h[electronic resource]  c2021  aEarly Access.  aEugenia copacabanensis and Myrciaria tenella are present in restingas of the Atlantic Forest, but little information is available about their chemical and biological potential. In this context, the hexane, dichloromethane, ethyl acetate and butanol fractions from the leaves of methanolic extract were analyzed by GC/MS and HPLC-DAD and the antioxidant potential was determined by DPPH and ABTS assays and using a Saccharomyces cerevisiae model. Dereplication allowed the identification of 68 compounds, 42 and 41 of which, respectively, are first reported here for E. copacabanensis and M. tenella. In vivo results revealed that the ethyl acetate and butanol fractions showed expressive antioxidant protection in the BY4741 and Delta gsh1 strains, with greater impact on glutathione-deficient cells. With a high diversity of phenolic compounds, these polar fractions of E. copacabanensis and M. tenella leaves are potential protectors against intracellular oxidative stress.  aAntioxidant activity  aEssential oils  aAlimento  aComposto Fenólico  aCrescimento  aExtração  aÓleo Essencial  aTecnologia de Alimento  aAtividade antioxidante  aCapacidade  aCapacity  aComponentes fenólicos  aDereplication  aDesreplicação  aEugenia copacabanensis  aGrowth  aModelo de fermento  aMyrciaria tenella  aProdutos naturais  aYeast model1 aFRANCA, L. P.1 aFERREIRA, Y. da S.1 aPIRES, D. C.1 aCARDOSO, B. de S.1 aSANTIAGO, M. C. P. de A.1 aPACHECO, S.1 aSOUZA, M. da C.1 aRIGER, C. J.1 aGODOY, R. L. de O.1 aCARVALHO, M. G. de  tChemistry & Biodiversity, 18, e2100054. 2021.