02588naa a2200349 a 450000100080000000500110000800800410001902400590006010000190011924501330013826000090027152015030028065000240178365000090180765000100181665000190182665300300184565300360187565300100191165300300192170000250195170000210197670000290199770000180202670000200204470000200206470000240208470000220210870000220213070000230215277300630217521163812024-02-06 2019 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1016/j.anireprosci.2019.1061372DOI1 aMACIELA, G. S. aFollicular dynamics and in vivo embryo production in Santa Inês ewes treated with smaller doses of pFSH.h[electronic resource] c2019 aAbstract: To evaluate follicular dynamics, there was assessment of superovulatory response and in vivo embryo production in ewes treated with relatively smaller doses of exogenous pFSH than typically used in combination with a dose of eCG at the beginning of the gonadotropin treatment period. Santa Inês ewes (n?=?24) were randomly divided into three groups, based on mg dose of pFSH administered: G200 (n?=?8), G133 (n?=?8) and G100 (n?=?8) in eight decreasing doses at 12?-h intervals. All ewes were treated with 300 IU of eCG concomitantly starting with first pFSH administration. Ovulatory follicular dynamics and follicular wall vascularization (FWV) were evaluated using a B-mode and color Doppler ultrasonic machine, respectively. Superovulatory response and embryo production were evaluated 6 days after estrous detection. In the G200?group, the preovulatory follicle size (PFS) were less (P?<? 0.05), ovulation time later (P?<? 0.05), and PFS rate greater (P?<? 0.05); while in the G100 group ovulation rate, and number and percentage of unfertilized eggs were greater (P?<? 0.05) than in the G133 group (P?<? 0.05). Number and percentage of viable embryos were greater in the G200 and G100 compared to G133 group (P?<? 0.05). The dose of 100 mg of FSH was as efficacious as the traditional dose of 200 mg, in combination with a dose of eCG, for superovulatory response and viable embryo production but there was a greater percentage of unfertilized eggs with this treatment. aAnimal reproduction aEwes aSheep aSuperovulation aApoptotic embryonic cells aFollicular wall vascularization aOvine aOvulatory follicular wave1 aRODRIGUEZA, M. G. K.1 aSANTOS, V. J. C.1 aRAMIREZ USCATEGUI, R. A.1 aNOCITI, R. P.1 aMARONEZI, M. C.1 aOLIVEIRA, C. S.1 aFELICIANO, M. A. R.1 aVICENTE, W. R. R.1 aFONSECA, J. F. da1 aOLIVEIRA, M. E. F. tAnimal Reproduction Sciencegv. 209, article 106137, 2019.