03048naa a2200289 a 450000100080000000500110000800800410001910000170006024501290007726000090020652021910021565000310240665000210243765000170245865000160247565300300249170000170252170000190253870000180255770000200257570000220259570000200261770000230263770000190266070000240267977300550270320994662019-01-29       2018    bl uuuu     u00u1 u    #d1 aLOPES, L. G.  aThe intake of dry cashew apple fiber reduced fecal egg counts in Haemonchus contortus-infected sheep.h[electronic resource]  c2018  aHelminthiasis is a common disease in which parasite resistance is frequently caused by inadequate administration of anthelmintics in small ruminant production. Since phytotherapy may be an adjuvant for parasite control, we assessed whether the ingestion of cashew apple fiber (Anacardium occidentale) would reduce Haemonchus contortus infection in Santa Inês sheep. Twenty-one male sheep with mean age of 240 ± 9.7 days were dewormed, infected with 4000 L3 of H. contortus Embrapa2010 (day 0 ? D0) and on D28 were divided into three equally sized experimental groups: 1) control (no treatment), 2) treated with anthelmintic (monepantel, 2.5 mg/kg PV) and 3) cashew apple fiber (0.3% BW) for 7 days of adaptation plus 28 days (D63). The animals were weighed weekly for diet adjustment and individual EPGs were performed twice a week. Corn silage was given ad libitum after each animal had eaten all the cashew apple fiber, which always occurred due to its palatable flavor. The silage, cashew apple fiber and leftovers were weighed daily and the samples were analyzed for dry matter. In cashew apple fiber, the total polyphenol contents were determined spectrophotometrically and the phenol compounds were identified by LC-MS. Cashew apple fiber contained 93.6% DM, 13.0% CP, 68.7% NDF, 47.6% FDA, 1.3% MM, 1.9% EE and 22.3% LIG. Twenty phenolic compounds were detected, among them phenolic acids and flavonoids, including glycosylated ones. The general EPG averages were statistically different among control, anthelmintic and cashew groups (3449, 14 and 2070, respectively), while the mean total weight gain did not differ (3.21, 3.20 and 1.94 kg, respectively) (p &lt 0.05). In relation to the control group, the anthelmintic showed efficacy of 99.6% and the cashew apple fiber 40.8%. Phenolic compounds appear to play an important role in the anthelmintic activity of cashew apple fiber. Thus, its use as an adjuvant in the control of H. contortus can be encouraged in regions where it is available at low cost, mitigating the use of veterinary drugs, reducing environmental contamination by agroindustrial residues and promoting the more sustainable production of small ruminants.  aGastrointestinal nematodes  aMedicinal plants  aPhytotherapy  aFitoterapia  aResíduos agroindustriais1 aSILVA, M. H.1 aFIGUEIREDO, A.1 aCANUTO, K. M.1 aBRITO, E. S. de1 aRIBEIRO, P. R. V.1 aSOUZA, A. S. Q.1 aBARIONI JUNIOR, W.1 aESTEVES, S. N.1 aCHAGAS, A. C. de S.  tExperimental Parasitologygv. 195, p. 38-43, 2018.