02528naa a2200397 a 450000100080000000500110000800800410001902200140006002400540007410000200012824501550014826000090030352013500031265000210166265000160168365000180169965000190171765000220173665000220175865000240178065000120180465300180181665300160183465300170185065300140186765300090188170000170189070000160190770000120192370000260193570000260196170000270198770000230201470000230203777300700206020988142018-11-06       2018    bl uuuu     u00u1 u    #d  a0147-65137 ahttps://doi.org/10.1016/j.ecoenv.2018.08.0932DOI1 aSILVA, G. H. da  aToxicity assessment of TiO2-MWCNT nanohybrid material with enhanced photocatalytic activity on Danio rerio (Zebrafish) embryos.h[electronic resource]  c2018  aAbstract: The increasing production and use of nanomaterials is causing serious concerns about their safety to human and environmental health. However, the applications of titanium dioxide nanoparticles (TiO2NP) and multiwalled carbon nanotubes (MWCNT) hybrids has grown considerably, due to their enhanced photocatalytic efficiency. To our knowledge, there are no reports available to the scientific community about their toxicity. In this work, we perform a toxicity assessment of TiO2NP and TiO2-MWCNT nanohybrid materials using Zebrafish embryos standardized 96?h early life stage assay, under different exposure conditions (with and without UV light exposure). After exposure the parameters assessed were acute toxicity, hatching rate, growth, yolk sac size, and sarcomere length. In addition, ?-probe X-ray fluorescence spectroscopy (µ-XRF) was employed to observe if nanoparticles were uptaken by zebrafish embryos and consequently accumulated in their organisms. Neither TiO2NP nor TiO2-MWCNT nanohybrids presented acute toxicity to the zebrafish embryos. Moreover, TiO2NP presents sublethal effects for total length (with and without UV light exposure) on the embryos. This work contributes to the understanding of the potential adverse effects of the emerging nanohybrid materials towards safe innovation approaches in nanotechnology.  aCarbon nanotubes  aDanio rerio  aEcotoxicology  aNanocomposites  aComposto Químico  aImpacto Ambiental  aPeixe de Água Doce  aToxidez  aNanocompostos  aNanohybrids  aNanotoxicity  aNanotubos  aTiO21 aCLEMENTE, Z.1 aKHAN, L. U.1 aCOA, F.1 aRODRIGUES NETO, L. L.1 aCARVALHO, H. W. P. de1 aCASTRO, V. L. S. S. de1 aMARTINEZ, D. S. T.1 aMONTEIRO, R. T. R.  tEcotoxicology and Environmental Safetygv. 165, p. 136-143, 2018.