03151naa a2200481 a 450000100080000000500110000800800410001902400350006010000240009524501170011926000090023652017220024565000140196765000170198165000250199865000260202365000170204965000150206665000120208165000190209365000220211265000300213465000270216465300250219165300300221665300280224665300250227465300080229965300200230765300260232765300240235365300160237765300260239365300290241965300200244870000200246870000200248870000180250870000230252670000160254970000250256577300790259020803862024-01-11       2017    bl uuuu     u00u1 u    #d7 a10.1007/s12602-016-9244-82DOI1 aMORAES, G. M. D. de  aFunctional properties of Lactobacillus mucosae strains isolated from Brazilian goat milk.h[electronic resource]  c2017  aAbstract: The search for probiotic candidates among lactic acid bacteria (LAB) isolated from food may uncover new strains with promising health and technological properties. Lactobacillus mucosae strains attracted recent research attention due to their ability to adhere to intestinal mucus and to inhibit pathogens in the gastrointestinal tract, both related to a probiotic potential. Properties of interest and safety aspects of three Lb. mucosae strains (CNPC006, CNPC007, and CNPC009) isolated from goat milk were investigated employing in vitro tests. The presence of genetic factors related to bile salt hydrolase production (bsh), intestinal adhesion properties (msa, map, mub, and ef-tu), virulence, and biogenic amine production were also verified. All strains exhibited the target map, mub, and ef-tu sequences; the msa gene was detected in CNPC006 and CNPC007 strains. Some of the searched sequences for virulence factors were detected, especially in the CNPC009 strain; all strains carried the hyl gene, related to the production of hyaluronidase. Lb. mucosae CNPC007 exhibited a high survival rate in simulated gastric and enteric conditions. Besides, all strains exhibited the bsh sequence, and CNPC006 and CNPC007 were able to deconjugate salts of glycodeoxycholic acid (GDC). Regarding technological properties for dairy product applications, a relatively higher milk acidification and clotting capacity, diacetyl production, and proteolytic activity were registered for CNPC007 in comparison to the other strains. Collectively, the results aim at Lb. mucosae CNPC007 as a promising probiotic candidate for application in dairy products, deserving further studies to confirm and explore its potential.  aGoat milk  aHealth foods  aLactic acid bacteria  aLactobacillus mucosae  aPharmacology  aProbiotics  aCaprino  aLeite de cabra  aNutrição humana  aProduto derivado do leite  aTecnologia de alimento  aAlimentos funcionais  aBactéria ácido láctica  aGastro-intestinal tract  aGenes de virulência  aLAB  aMilk byproducts  aPotencial probiótico  aProbiotic potential  aProbiótico  aProdutos probióticos  aTechnological properties  aVirulence genes1 aABREU, L. R. de1 aEGITO, A. S. do1 aSALLES, H. O.1 aSILVA, L. M. F. da1 aNERO, L. A.1 aSANTOS, K. M. O. dos  tProbiotics and Antimicrobial Proteinsgv. 9, n. 3, p. 235-245, Sept. 2017.