02911naa a2200457 a 450000100080000000500110000800800410001902400380006010000220009824501920012026000090031252015660032165000280188765000100191565000130192565000100193865000140194865000140196265000170197665000220199365000120201565000160202765000290204365000160207265000150208865000240210365000230212765300170215065300280216765300220219565300140221765300140223165300200224570000170226570000270228270000230230970000170233270000200234970000130236977300710238220747112018-05-23       2017    bl uuuu     u00u1 u    #d7 a10.1016/j.repbio.2017.07.0022DOI1 aFONSECA, J. F. da  aReproductive features and use of an anti-inflammatory drug in estrus-induced dairy goats artificially inseminated in a standing position with cervix immobilization.h[electronic resource]  c2017  aAbstract: This study evaluated reproductive features and role of Flunixin-Meglumine at timed artificial insemination (AI), using a new technique of standing position with cervix immobilization. In Experiment 1, 10 goats (n=5 nulliparous [Null] and 5 pluriparous [Plu]) were evaluated after estrus induction by recorded reproductive parameters to define the ideal time for AI. In Experiment 2, goats were artificially inseminated 51-54h after sponge removal with frozen-thawed semen. At AI, 1mL saline (CONTROL; 18 Null and 14 Plu) or 50mg Flunixin-Meglumine (FLUNIXIN; 15 Null and 18 Plu) was administered i.m. Location of semen deposition was recorded for both groups. In Experiment 1, all sexual behavior and ovulatory parameters were similar between Null and Plu for estrus response and ovulation (100%), interval from sponge removal to ovulation (?64.2h), largest ovulatory follicle diameter (?6.6mm), and number of ovulations (?2.0). In Experiment 2, pregnancy rate was superior (P&lt0.01) for CONTROL (62.5%; 10 Null and 10 Plu) than FLUNIXIN (30.3%; 3 Null and 7 Plu) goats. Regardless of the treatment, intrauterine AI was more frequent (P&lt0.01) in Plu (100.0%; 32/32) than in Null (69.7%; 23/33) goats. Moreover, AI was more time-consuming (P&lt0.01) in Null (44±37s; 4-139s) than in Plu (21±19s, 4-78s) goats. Therefore, administration of Flunixin-Meglumine at the time of AI adversely affected pregnancy rate. High rates of intrauterine cervical penetration were obtained, achieving good pregnancy rates in goats not receiving Flunixin-Meglumine.  aArtificial insemination  aDrugs  aFlunixin  aGoats  aOvulation  aPregnancy  aReproduction  aAntiinflamatório  aCaprino  aFertilidade  aInseminação artificial  aMedicamento  aOvulação  aReprodução animal  aTaxa de natalidade  aAI technique  aAntiinflammatory agents  aEmbryo Technology  aFertility  aMeglumine  aTaxa de prenhez1 aALVIM, G. P.1 aSOUZA-FABJAN, J. M. G.1 aOLIVEIRA, M. E. F.1 aBRAIR, V. L.1 aBRANDÃO, F. Z.1 aFACO, O.  tReproductive Biology, Olsztyngv. 17, n. 3, p. 268-273, Sep. 2017.