03568naa a2200421 a 450000100080000000500110000800800410001910000210006024501430008126000090022452023500023365000180258365000190260165000210262065000100264165000140265165000110266565000130267665000240268965000200271365000170273365000120275065000220276265000290278465000150281365300170282865300220284565300170286765300180288465300210290265300210292365300230294465300310296770000220299870000200302070000200304077300860306011071952002-05-14       1989    bl uuuu     u00u1 u    #d1 aVIEIRA, L. da S.  aAtividade in Vitro dos BenzimidazóisbOxfendazole, Fenbendazole, Albendazole e Thiabendazole em Nematódeos Gastrintestinais de Caprinos.  c1989  aResumo: 0 trabalho foi executado com o objetivo de determinar e comparar a atividade "in vitro" dos benzimidazóis: oxfendazole, fenbendazole, aIbendazole e thiabendazole em nematódeos gastrintestinais, de caprinos. Para isto, realizaram-se coproculturas que foram tratadas corn anti-helmínticos benzimidazóis, em cinco concentrações diferentes: 6,25; 12,5; 25,0; 50,0 e 100,0 ppm, para cada um dos produtos, corn cinco coproculturas por concentração. Grupos de coproculturas que serviram de testemunha receberam água destilada. 0 thiabendazole e o aIbendazole, independentemente da concentraçao testada, apresentaram os maiores percentuais de reduçao de larvas infectantes de Haemonchus, Strongyloides e fêmeas, de Strongyloides de vida livre, ficando o oxfendazole numa posiçao intermediária e o fenbendazole na posiçao mais baixa. Para larvas infectantes de TrichostrongylusI, o oxfendazole, o aIbendazole e o thiabendazole apresentaram percentagens de reduçao acima de 95,0%, sendo que o fenbendazole apresentou percentuais de reduçao inferiores a 95,0%. Para as larvas infectantes de Oesophagostomun, os quatro benzimidazois testados apresentaram  apresentaram percentagens de reduçao lK:ima de 96,0%.  [In vitro activity of benzimidazoles: oxfendazole, fenbendazole, albendazole and thiabendazole in goat gastrintestinal nematodes].  Abstract: This study was carried out to determine and to compare lhe "in vitro" activity of the benzimidazoles oxfendazole, fenbendazoie, albendazole and thiabendazole on caprino gastrointestinal nematodes. Fecal culturas were performed and treated with benzimidazole anthelminths using tive different wncentralions 6,25, 12,5, 25.0, 50.0 and 100.0 ppm, Five fecal cultures were prepared for each coneerüation, using distilled water in the control cultures. Thiabendazole and albendazole, showed lhe highest reduction percentage of infeclive larvae of Haemonchus, Strongyloides and of the living females of Stongyloides. Oxfendazole ranked in an intertnediate position, and lenbendazole had lhe lowesi efficacy.  Against lhe infectivo larvae of Trichosfrongytus, oxtendazale, albendazole and Üiiabendazole had efficacy higher ilian 95%, whereas fenbendazole was lower 95.0%. Infective larvae ai Oesophagostomum were reduced by all four benzimidazoles tested with efficiencies above 96%.  aAnthelmintics  aBenzimidazoles  aChemical control  aGoats  aHelminths  aLarvae  aNematoda  aNematode infections  aAnti-helmintico  aBenzimidazol  aCaprino  aControle químico  aHelminto gastrintestinal  aNematóide  aAnthelmintic  aanti-helmínticos  acoprocultura  aFecal culture  aInfective larvae  aLarva infectante  alarvas infectantes  aNematódeo gastrintestinal1 aGONÇALVES, P. C.1 aCOSTA, C. A. F.1 aBERNE, M. E. A.  tPesquisa Agropecuária Brasileira, Brasíliagv.24, n.10, p. 1201-1209, out. 1989