02636naa a2200577 a 450000100080000000500110000800800410001902400560006010000250011624501290014126000090027052009240027965000290120365000110123265000190124365000200126265000130128265000350129565000180133065000210134865000230136965000240139265000100141665000150142665000220144165300110146365300420147465300350151665300360155165300140158765300270160165300400162865300300166865300140169865300200171265300160173270000170174870000190176570000190178470000170180370000130182070000190183370000210185270000230187370000240189670000230192070000190194370000260196270000230198877300470201120693692017-08-25 2017 bl uuuu u00u1 u #d7 ahttp://dx.doi.org/10.1016/j.livsci.2017.01.0062DOI1 aGOUVEIA, J. J. de S. aGenome-wide search for signatures of selection in three major Brazilian locally adapted sheep breeds.h[electronic resource] c2017 aAbstract: The study of locally adapted breeds has the potential to underpin the discovery of genes involved in economically and ecologically important traits. Brazilian locally adapted sheep breeds have distinctive characteristics that could be of value for specialized production systems. Therefore, the main objective of the present study was to identify genomic regions that may have been under selection and therefore may explain ecological and production differences observed among three important Brazilian locally adapted sheep breeds. Animals from the Brazilian Creole, Morada Nova and Santa Ines breeds were genotyped using the Illumina Ovine SNP50 BeadChip. The identification of selection signatures was based on two groups of methodologies: differentiation among populations (FST) and linkage disequilibrium (iHS and RsB). Taken together, these analyses allowed for the identification of 86 candidate genes. aAnimal genetic resources aBrazil aclimate change aGenetic markers aGenomics aSingle nucleotide polymorphism aConservação aGenética animal aMarcador genético aMudança Climática aOvino aOvis Aries aRecurso genético aBrasil aConservation animal genetic resources aGenetic resources conservation aGenome wide association studies aGenômica aLocally adapted breeds aNucleotídeo de polimorfismo único aRaça localmente adaptada aSelection aSelective sweep aSNP markers1 aPAIVA, S. R.1 aMCMANUS, C. M.1 aCAETANO, A. R.1 aKIJAS, J. W.1 aFACO, O.1 aAZEVEDO, H. C.1 aARAUJO, A. M. de1 aSOUZA, C. J. H. de1 aYAMAGISHI, M. E. B.1 aCARNEIRO, P. L. S.1 aLOBO, R. N. B.1 aOLIVEIRA, S. M. P. de1 aSILVA, M. V. G. B. tLivestock Sciencegn. 197, p. 36-45, 2017.