01258nam a2200277 a 450000100080000000500110000800800410001910000190006024501000007926001980017930000190037750000360039652002980043265000190073065000230074965300200077265300210079265300150081365300410082865300230086970000250089270000140091770000190093170000160095070000140096620622292020-01-07       2016    bl uuuu     u00u1 u    #d1 aSCHULTZ, L. G.  aThe host/guest interactions of the key protein for the bipolar disorder.h[electronic resource]  aIn: ANNUAL MEETING OF THE BRAZILIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 45., 2016, Natal. Livro de resumos... [Natal]: Sociedade Brasileira de Bioquímica e Biologia Molecularc2016  aNão paginado.  aNa publicação: José Jardine.  aOur idea is to use hesperitin as a candidate to inhibit IMPase 2, motivated mainly by its capacity to easily cross the bloodbrain barrier and also due to its low or absent toxicity. Our research started with computational biology tools to verify in silico hesperetin and IMPase 2 interactions.  aBioinformatics  aBiologia molecular  aBioinformática  aBipolar disorder  aHesperitin  aInositolmonophosphatase 2 (IMPase 2)  aTranstorno bipolar1 aVILLALTA­ROMERO, F.1 aBORRO, L.1 aJARDINE, J. G.1 aNESHICH, G.1 aTASIC, L.