02333naa a2200493 a 450000100080000000500110000800800410001902400350006010000210009524501460011626000090026252009460027165000150121765300080123265300090124065300090124970000220125870000170128070000190129770000260131670000180134270000170136070000220137770000150139970000220141470000160143670000190145270000200147170000210149170000230151270000230153570000200155870000250157870000180160370000230162170000180164470000310166270000170169370000180171070000200172870000170174870000260176577300480179120537142019-03-12       2016    bl uuuu     u00u1 u    #d7 a10.1186/s12864-016-2535-32DOI1 aMUDADU, M. de A.  aGenomic structure and marker-derived gene networks for growth and meat quality traits of brazilian nelore beef cattle.h[electronic resource]  c2016  aNelore is the major beef cattle breed in Brazil with more than 130 million heads. Genome-wide association studies (GWAS) are often used to associate markers and genomic regions to growth and meat quality traits that can be used to assist selection programs. An alternative methodology to traditional GWAS that involves the construction of gene network interactions, derived from results of several GWAS is the AWM (Association Weight Matrices)/PCIT (Partial Correlation and Information Theory). With the aim of evaluating the genetic architecture of Brazilian Nelore cattle, we used high-density SNP genotyping data (~770,000 SNP) from 780 Nelore animals comprising 34 half-sibling families derived from highly disseminated and unrelated sires from across Brazil. The AWM/PCIT methodology was employed to evaluate the genes that participate in a series of eight phenotypes related to growth and meat quality obtained from this Nelore sample.  agenotyping  aAWM  aGWAS  aPCIT1 aPORTO NETO, L. R.1 aMOKRY, F. B.1 aTIZIOTO, P. C.1 aOLIVEIRA, P. S. N. de1 aTULLIO, R. R.1 aNASSU, R. T.1 aNICIURA, S. C. M.1 aTHOLON, P.1 aALENCAR, M. M. de1 aHIGA, R. H.1 aROSA, A. do N.1 aFEIJO, G. L. D.1 aFERRAZ, A. L. J.1 aSILVA, L. O. C. da1 aMEDEIROS, S. R. de1 aLANNA, D. P. D.1 aNASCIMENTO, M. L. do1 aCHAVES, A. S.1 aSOUZA, A. R. D. L.1 aPACKER, I. U.1 aTORRES JUNIOR, R. A. de A.1 aSIQUEIRA, F.1 aMOURAO, G. B.1 aCOUTINHO, L. L.1 aREVERTER, A.1 aREGITANO, L. C. de A.  tBMC Genomicsgv. 17, n. 235, p. 1-16, 2016.