02088naa a2200337 a 450000100080000000500110000800800410001902400570006010000130011724501380013026000090026852011090027765000200138665000270140665000350143365000100146865000340147865000270151265000110153965300350155070000120158570000120159770000110160970000130162070000120163370000130164570000190165870000170167770000140169477300420170820316262015-12-14       2015    bl uuuu     u00u1 u    #d7 ahttp://dx.doi.org/10.1016/j.meatsci.2015.06.0112DOI1 aHONG, J.  aEffects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition.h[electronic resource]  c2015  aThis study aimed to verify genetic relationships between fatty acid composition (FAC) and genotypes of several genes (FABP3, HMGA1, MC4R, IGF2, and FABP4) using pig breeds. The effects of genetic variations on FAC of the longissimus muscle were statistically significant with additive and dominance effects. The polymorphisms of FABP3 and IGF2 had the largest effects on stearic (C18:0, P = 0.009) and γ-linoleic (C18:3n6, P = 0.039) acids, respectively, whereasHMGA1 and FABP4 did not show significances. The analysis revealed that MC4R was significantly associated with palmitoleic acid (C16:ln7) and MUFA. Allele frequencies of the genes examined in this analysis were significantly skewed or fixed in the Korean native pig (KNP), whereas the allele frequencies of the crossbreds tended to fall between those of the purebreds except that HMGA1 and FABP4 had approximately the same allele frequencies with Duroc and KNP, respectively. The polymorphisms found in this study could be used as genetic markers in breeding programs to simultaneously change proportions of fatty acids in muscle tissues.  aAnimal genetics  afatty acid composition  aSingle nucleotide polymorphism  aSwine  aMelhoramento genético animal  aPolimorfismo genético  aSuíno  aComposição de ácidos graxos1 aKIM, D.1 aCHO, K.1 aSA, S.1 aCHOI, S.1 aKIM, Y.1 aPARK, J.1 aSCHMIDT, G. S.1 aDAVIS, M. E.1 aCHUNG, H.  tMeat Sciencegv. 110, p. 46-51, 2015.