03104naa a2200361 a 450000100080000000500110000800800410001902400430006010000230010324501220012626000090024852020350025765000230229265000100231565000130232565000120233865000290235065000150237965000270239465300080242165300120242965300170244165300310245865300230248970000210251270000320253370000170256570000200258270000250260270000210262770000170264877300770266520069992016-03-04 2015 bl uuuu u00u1 u #d7 a10.1016/j.smallrumres.2014.10.0022DOI1 aCOUTINHO, R. M. A. aPhenotypic markers to characterize F2 crossbreed goats infected by gastrointestinal nematodes.h[electronic resource] c2015 aAbstract: The aim of this study was to evaluate and characterize goats with different levels of resistance to gastrointestinal parasitic nematodes. During 93 days, 60 F2 crossbreed goats originated from ½ Saanen and ½ Anglo-Nubian animals were grazed in the same pasture. Feces and blood were collected on a weekly basis for eggs per gram counts of feces (EPG) and coprocultures and to determinate the number of eosinophils, packed cell volume and total plasma protein, respectively. On the same day, the animals were weighed, they body condiction was scored and their degree of anemia estimated by FAMACHA card. Based on the average values of EPG, the 12 animals with the highest average of EPG (susceptible group) and the 12 animals with the lowest average of EPG (resistant group) were selected, slaughtered and necropsied for counting and parasites identification. The resistant animals presented lower EPG counts (P < 0.0001) and 4.7 folder less parasites than susceptible animals. The resistant group also presented a higher average of packed cell volume (26.48%) and total plasma protein (6.24 g/dl) than susceptible one (24.04% and 5.82 g/dl, respectively). The average of number of eosinphils was similar among groups. The weight of resistant animals was higher than susceptible group (23.17 kg and 19.17 kg, respectively; P < 0.05), with better body condition score than the susceptible counterparts. The resistant animal had higher FAMACHA at class 1 (20%) than the susceptible one (5.26%), with FAMACHA 4 (4.21%). Haemonchus sp. was the most prevalent in the coprocultures, followed by Trichostrongylus sp. and Oesophagostomum sp. The number of nematodes in the abomasum was higher in susceptible group than in resistant one. The species identified were Haemonchus contortus in abomasum and Trichstrongylus colubriformis in small intestine. The EPG, packed cell volume and total plasma protein were useful phenotypic markers to identify resistant and susceptible animals to gastrointestinal nematodes infections. aGenetic resistance aGoats aNematoda aCaprino aHelminto gastrintestinal aNematóide aResistência genética aEPG aFAMACHA aHematócrito aNematódeo gastrintestinal aPacked cell volume1 aBENVENUTI, C. L.1 aANDRADE JUNIOR, A. L. F. de1 aSILVA, F. C.1 aNEVES, M. R. M.1 aNAVARRO, A. M. do C.1 aVIEIRA, L. da S.1 aZAROS, L. G. tSmall Ruminant Research, Amsterdamgv. 123, n. 1, p. 173-178, Jan. 2015.