Registro Completo
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
06/03/2009 |
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Data da última atualização: |
12/06/2025 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LIU, G. E.; LI, R. W.; SONSTEGARD, T. S.; MATUKUMALLI, L. K.; SILVA, M. V. G. B.; VAN TASSELL, C. P. |
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Afiliação: |
USDA; R.W. LI, USDA-ARS; TAD S. SONSTEGARD, USDA; LAKSHMI MATUKUMALLI, GEORGE MASON UNIVERSITY; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; CURTIS VAN TASSELL, USDA. |
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Título: |
Characterization of a novel microdeletion polymorphism on BTA5 in cattle. |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
Animal Genetics, v. 39, n. 6, p. 655-658, 2008. |
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DOI: |
https://doi.org/10.1111/j.1365-2052.2008.01769.x |
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Idioma: |
Inglês |
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Conteúdo: |
We present a detailed breakpoint mapping and population frequency analysis of a 214-kb microdeletion that removes multiple olfactory receptor genes. Using progressive rounds of PCR assays, we mapped the upstream and downstream breakpoints of this microdeletion event to 1 and 12 kb genomic regions, respectively. We developed PCR-based genotyping assays, characterized a dairy cattle panel of 96 samples and found that the frequency of the deletion allele was over 51%. Our results indicated that this microdeletion is an ancient event occurring in one of the earlier founders, and that it has been stably inherited across generations in the North American dairy cattle population. |
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Palavras-Chave: |
Breakpoint; Cattle genome; Deletion; Population frequency; Structural variants. |
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Categoria do assunto: |
-- |
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URL: |
https://www.alice.cnptia.embrapa.br/alice/bitstream/doc/596819/1/Characterization-of-a-novel-microdeletion-polymorphism-on-BTA5-in-cattle.pdf
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Marc: |
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
