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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
14/10/2015 |
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Data da última atualização: |
03/12/2015 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
JESUS, D. R.; BARBOSA, L. N.; PRANDO, T. B. L.; MARTINS, L. F.; GASPAROTTO, F.; GUEDES, K. M. R.; DRAGUNSKI, D. C.; LOURENÇO, E. L. B.; DALSENTER, P. R.; GASPAROTTO JUNIOR, A. |
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Afiliação: |
DOUGLAS ROSSI JESUS, UNIPAR - Universidade Paranaense; LORENA NERIS BARBOSA, UFPR; THIAGO BRUNO LIMA PRANDO, UNIPAR; LEONARDO FRANCO MARTINS, UNIPAR; FRANCIELLI GASPAROTTO, CESUMAR; KARLA MORAES ROCHA GUEDES, CPAP; DOUGLAS CARDOSO DRAGUNSKI, UNIPAR; EMERSON LUIZ BOTELHO LOURENÇO, UNIPAR; PAULO ROBERTO DALSENTER, UFPR; ARQUIMEDES GASPAROTTO JUNIOR, UFGD. |
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Título: |
Ninety-day oral toxicity assessment of an alternative biopolymer for controlled release drug delivery systems obtained from cassava starch acetate. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Evidence-Based Complementary and Alternative Medicine, 2015. |
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DOI: |
10.1155/2015/390416 |
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Idioma: |
Inglês |
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Conteúdo: |
The large consumption of biodegradable films from cassava starch acetate (FCSA) as ingredients in food and pharmaceutical products requires the assessment of the possible toxicity of these products. The aim of this study was to investigate the toxicity of biodegradable film from cassava starch acetate after oral exposure of Wistar rats for 90 days. The amount of food consumed and the body weight were weekly monitored. Blood and urine samples were obtained for the assessment of serum parameters and renal function. Histopathological analyses in target organs were also performed. No evidence of clinical toxicity in hematological, biochemical, or renal parameters in the FCSA-treated animals was found. In addition, relative organ weight and histopathological evaluations did not differ between groups treated with FCSA and control. Data obtained suggest that the subchronic exposure to FCSA does not cause obvious signs of toxicity inWistar rats, indicating possible safety of this biofilm. |
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Palavras-Chave: |
Biodegradable films; Degradable products; FCSA. |
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Thesagro: |
Mandioca; Manihot Esculenta; Tóxico. |
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Thesaurus Nal: |
Biodegradation. |
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Categoria do assunto: |
E Economia e Indústria Agrícola |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/134837/1/Ninety-Day-Oral-Toxicity-Assessment-of-an-Alternative.pdf
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Marc: |
LEADER 01972naa a2200325 a 4500
001 2026401
005 2015-12-03
008 2015 bl uuuu u00u1 u #d
024 7 $a10.1155/2015/390416$2DOI
100 1 $aJESUS, D. R.
245 $aNinety-day oral toxicity assessment of an alternative biopolymer for controlled release drug delivery systems obtained from cassava starch acetate.
260 $c2015
520 $aThe large consumption of biodegradable films from cassava starch acetate (FCSA) as ingredients in food and pharmaceutical products requires the assessment of the possible toxicity of these products. The aim of this study was to investigate the toxicity of biodegradable film from cassava starch acetate after oral exposure of Wistar rats for 90 days. The amount of food consumed and the body weight were weekly monitored. Blood and urine samples were obtained for the assessment of serum parameters and renal function. Histopathological analyses in target organs were also performed. No evidence of clinical toxicity in hematological, biochemical, or renal parameters in the FCSA-treated animals was found. In addition, relative organ weight and histopathological evaluations did not differ between groups treated with FCSA and control. Data obtained suggest that the subchronic exposure to FCSA does not cause obvious signs of toxicity inWistar rats, indicating possible safety of this biofilm.
650 $aBiodegradation
650 $aMandioca
650 $aManihot Esculenta
650 $aTóxico
653 $aBiodegradable films
653 $aDegradable products
653 $aFCSA
700 1 $aBARBOSA, L. N.
700 1 $aPRANDO, T. B. L.
700 1 $aMARTINS, L. F.
700 1 $aGASPAROTTO, F.
700 1 $aGUEDES, K. M. R.
700 1 $aDRAGUNSKI, D. C.
700 1 $aLOURENÇO, E. L. B.
700 1 $aDALSENTER, P. R.
700 1 $aGASPAROTTO JUNIOR, A.
773 $tEvidence-Based Complementary and Alternative Medicine, 2015.
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Registro original: |
Embrapa Pantanal (CPAP) |
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Registro |
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Registro Completo
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Biblioteca(s): |
Embrapa Uva e Vinho. |
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Data corrente: |
23/10/2008 |
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Data da última atualização: |
22/10/2019 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
CAMARGO, U. A.; MAIA, J. D. G.; SILVA, G. A. da; ZANUS, M. C.; GUERRA, C. C.; RITSCHEL, P. S. |
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Afiliação: |
Umberto Almeida Camargo, CNPUV; JOAO DIMAS GARCIA MAIA, CNPUV; GILDO ALMEIDA DA SILVA, CNPUV; MAURO CELSO ZANUS, CNPUV; CELITO CRIVELLARO GUERRA, CNPUV; PATRICIA SILVA RITSCHEL, CNPUV. |
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Título: |
New Brazilian grape cultivars for juice. |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
In: CONGRESSO MONDIALE DELLA VIGNA E DEL VINO, 31.; ASSEMBLEA GENERALE DELL'O.I.V., 6., 2008, Verona, Italia. Riassunti delle comunicazioni. [Verona]: OIV: Ministero Politiche Agricole, Alimentari e Forestali, 2008. |
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Páginas: |
p. 45. |
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Idioma: |
Inglês |
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Notas: |
Resumo I.D.2. |
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Conteúdo: |
The production of grape juice in Brazil is based on cultivars and hybrids of Vitis labrusca, among which the cultivars Isabel, Concord and Bordô stand out. |
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Palavras-Chave: |
Brasil; Melhoramento genético. |
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Thesagro: |
Cruzamento; Suco; Uva; Variedade; Viticultura. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/203407/1/10135-2008-p.45.pdf
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Marc: |
LEADER 01028nam a2200277 a 4500
001 1543077
005 2019-10-22
008 2008 bl uuuu u00u1 u #d
100 1 $aCAMARGO, U. A.
245 $aNew Brazilian grape cultivars for juice.$h[electronic resource]
260 $aIn: CONGRESSO MONDIALE DELLA VIGNA E DEL VINO, 31.; ASSEMBLEA GENERALE DELL'O.I.V., 6., 2008, Verona, Italia. Riassunti delle comunicazioni. [Verona]: OIV: Ministero Politiche Agricole, Alimentari e Forestali$c2008
300 $ap. 45.
500 $aResumo I.D.2.
520 $aThe production of grape juice in Brazil is based on cultivars and hybrids of Vitis labrusca, among which the cultivars Isabel, Concord and Bordô stand out.
650 $aCruzamento
650 $aSuco
650 $aUva
650 $aVariedade
650 $aViticultura
653 $aBrasil
653 $aMelhoramento genético
700 1 $aMAIA, J. D. G.
700 1 $aSILVA, G. A. da
700 1 $aZANUS, M. C.
700 1 $aGUERRA, C. C.
700 1 $aRITSCHEL, P. S.
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Registro original: |
Embrapa Uva e Vinho (CNPUV) |
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Origem |
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