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| Registros recuperados : 34 | |
| 3. |  | SCRAMIN, S.; CHAIM, A.; PESSOA, M. C. P. Y.; FERRACINI, V. L.; PAVAN, L. A.; ALVARENGA, N. Avaliação de bicos de pulverização de agrotóxicos na cultura do algodão. Pesticidas: Revista de Ecotoxicologia e Meio Ambiente, Curitiba, v.12, p.43-50, 2002| Biblioteca(s): Embrapa Meio Ambiente. |
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| 9. | | SAMPAIO, A. C. F.; SILVA, E. S.; CARMO, I. L. G. da S.; MONTEIRO NETO, J. L. L.; MENESES, P. H. S.; MEDEIROS, R. D. de. Qualidade de frutos de cultivares de melancia no Cerrado de Boa Vista, Roraima. In: SEMANA NACIONAL DE CIÊNCIA E TECNOLOGIA NO ESTADO DE RORAIMA, 10., 2015, Boa Vista. Resumos... Boa Vista, RR: UERR, 2015.| Biblioteca(s): Embrapa Roraima. |
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| 13. | | GASPAR, E. B.; SANTOS, L. R. dos; EGITO, A. A. do; SANTOS, M. G. dos; MANTOVANI, C.; RIEGER, J. DA S. G.; ABRANTES, G. A. DE S.; SUNIGA, P. A. P.; FAVACHO, J. DE M.; PINTO, I. B.; NASSAR, A. F. DE C.; SANTOS, F. L. DOS; ARAUJO, F. R. Assessment of the virulence of the Burkholderia mallei Strain BAC 86/19 in BALB/c Mice. Microorganisms, v. 11, issue 10, e2597, 2023.| Biblioteca(s): Embrapa Gado de Corte; Embrapa Pecuária Sul. |
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| 14. | | MORES, N.; AMARAL, A. L. do; LIMA, G. J. M. M. de; DALLA COSTA, O. A.; COLDEBELLA, A.; MIELE, M.; SANDI, A. J.; OLIVEIRA, P. A. V. de. Produção de suínos em família, sem uso preventivo de antimicrobiano e privilegiando o bem-estar animal. Concórdia: Embrapa Suínos e Aves, 2013 118 p. (Embrapa Suínos e Aves. Sistemas de Produção, 5).| Biblioteca(s): Embrapa Suínos e Aves. |
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| 19. | | CATULLO, J. C.; RODRIGUEZ, M. L.; SOSA, C. A.; COLOMBO, I. Determinacion del periodo critico de competencia de las malezas en el cultivo de girasol. Malezas; Revista de la Asociacion Argentina para el Control de Malezas, Buenos Aires, v.11, n.4, p.150-164, 1983. Trabalho apresentado na IX Reunion Argentina sobre la Maleza y su Control, Santa Fe, agosto de 1982.| Biblioteca(s): Embrapa Soja. |
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| Registros recuperados : 34 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Gado de Corte; Embrapa Pecuária Sul. |
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Data corrente: |
29/11/2023 |
|
Data da última atualização: |
30/11/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 3 |
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Autoria: |
GASPAR, E. B.; SANTOS, L. R. dos; EGITO, A. A. do; SANTOS, M. G. dos; MANTOVANI, C.; RIEGER, J. DA S. G.; ABRANTES, G. A. DE S.; SUNIGA, P. A. P.; FAVACHO, J. DE M.; PINTO, I. B.; NASSAR, A. F. DE C.; SANTOS, F. L. DOS; ARAUJO, F. R. |
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Afiliação: |
EMANUELLE BALDO GASPAR, CPPSUL; LENITA RAMIRES DOS SANTOS, CNPGC; ANDREA ALVES DO EGITO, CNPGC; MARIA GORETTI DOS SANTOS, CNPGC; CYNTHIA MANTOVANI, CNPGC; JULIANA DA SILVA GOMES RIEGER, CNPGC; GUILHERME AUGUSTO DE SOUSA ABRANTES, CNPGC; PAULA ADAS PEREIRA SUNIGA, UNIVERSIDADE FEDERAL DE MATO GROSSO DO SUL; JÚLIA DE MENDONÇA FAVACHO, CNPGC; INGRID BATISTA PINTO, CNPGC; ALESSANDRA FIGUEIREDO DE CASTRO NASSAR, CENTER FOR RESEARCH AND DEVELOPMENT IN ANIMAL HEALTH; FERNANDO LEANDRO DOS SANTOS, UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO; FLABIO RIBEIRO DE ARAUJO, CNPGC. |
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Título: |
Assessment of the virulence of the Burkholderia mallei Strain BAC 86/19 in BALB/c Mice. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Microorganisms, v. 11, issue 10, e2597, 2023. |
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DOI: |
https://doi.org/10.3390/microorganisms11102597 |
|
Idioma: |
Inglês |
|
Conteúdo: |
ABSTRACT - Burkholderia mallei is an aerobic, Gram-negative, non-motile bacillus. As an obligate mammalian pathogen, it primarily affects solipeds. Although rarely transmitted to humans, the disease it causes, glanders, is classified as a zoonosis. The bacterium was officially eradicated in Brazil in 1969; however, it reemerged after three decades. This study aims to assess the virulence of a specific B. mallei strain, isolated in Brazil, in BALB/c mice through intranasal infection. The strain, B. mallei BAC 86/19, was obtained from the tracheal secretion of a young mare displaying positive serology but no clinical signs of glanders. Post-mortem examinations revealed macroscopic lesions consistent with the disease, however. In mice, the LD50 was determined to be approximately 1.59 × 105 colony-forming units (CFU)/animal. Mice exposed to either 0.1 × LD50 or 1 × LD50 displayed transient
weight loss, which resolved after three or five days, respectively. B. mallei persisted within the liver and lung for five days post-infection and in the spleen for seven days. These findings underscore the detectable virulence of the Brazilian B. mallei BAC 86/19 strain in mice, which are relatively resilient hosts. This research points to the importance of the continued investigation of the virulence mechanisms and potential countermeasures associated with B. mallei infections, including their Brazilian isolates. |
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Thesagro: |
Doença Animal; Zoonose. |
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Thesaurus NAL: |
Animal diseases; Animal models; Burkholderia mallei; Glanders; Pathogenicity; Virulence; Zoonoses. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1158893/1/Assessment-virulence-Burkholderia-mallei-strain-2023.pdf
|
|
Marc: |
LEADER 02528naa a2200385 a 4500
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024 7 $ahttps://doi.org/10.3390/microorganisms11102597$2DOI
100 1 $aGASPAR, E. B.
245 $aAssessment of the virulence of the Burkholderia mallei Strain BAC 86/19 in BALB/c Mice.$h[electronic resource]
260 $c2023
520 $aABSTRACT - Burkholderia mallei is an aerobic, Gram-negative, non-motile bacillus. As an obligate mammalian pathogen, it primarily affects solipeds. Although rarely transmitted to humans, the disease it causes, glanders, is classified as a zoonosis. The bacterium was officially eradicated in Brazil in 1969; however, it reemerged after three decades. This study aims to assess the virulence of a specific B. mallei strain, isolated in Brazil, in BALB/c mice through intranasal infection. The strain, B. mallei BAC 86/19, was obtained from the tracheal secretion of a young mare displaying positive serology but no clinical signs of glanders. Post-mortem examinations revealed macroscopic lesions consistent with the disease, however. In mice, the LD50 was determined to be approximately 1.59 × 105 colony-forming units (CFU)/animal. Mice exposed to either 0.1 × LD50 or 1 × LD50 displayed transient weight loss, which resolved after three or five days, respectively. B. mallei persisted within the liver and lung for five days post-infection and in the spleen for seven days. These findings underscore the detectable virulence of the Brazilian B. mallei BAC 86/19 strain in mice, which are relatively resilient hosts. This research points to the importance of the continued investigation of the virulence mechanisms and potential countermeasures associated with B. mallei infections, including their Brazilian isolates.
650 $aAnimal diseases
650 $aAnimal models
650 $aBurkholderia mallei
650 $aGlanders
650 $aPathogenicity
650 $aVirulence
650 $aZoonoses
650 $aDoença Animal
650 $aZoonose
700 1 $aSANTOS, L. R. dos
700 1 $aEGITO, A. A. do
700 1 $aSANTOS, M. G. dos
700 1 $aMANTOVANI, C.
700 1 $aRIEGER, J. DA S. G.
700 1 $aABRANTES, G. A. DE S.
700 1 $aSUNIGA, P. A. P.
700 1 $aFAVACHO, J. DE M.
700 1 $aPINTO, I. B.
700 1 $aNASSAR, A. F. DE C.
700 1 $aSANTOS, F. L. DOS
700 1 $aARAUJO, F. R.
773 $tMicroorganisms$gv. 11, issue 10, e2597, 2023.
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Embrapa Pecuária Sul (CPPSUL) |
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