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| Registros recuperados : 28 | |
| 4. |  | SANTOS, S. A.; SORIANO, B. M. A.; CRISPIM, S. M. A.; CARDOSO, E. L.; PELLEGRIN, L. A. Indicador para Avaliação do Grau de Severidade das Queimadas e Incêndios em Fazendas do Pantanal. In: ENCONTRO CIENTÍFICO DA ZOOTECNIA, 3., 2013, Aquidauana, MS. Resumos... Aquidauana: UEMS, 2013.| Biblioteca(s): Embrapa Pantanal. |
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| 5. | | HIGARASHI, M. M.; SARDÁ, L. G.; OLIVEIRA, P. A. V. D.; COMIN, J. J.; CURIOLETTI, F.; BRINGHENTI, M.; MATTEI, R. M. Influência da diluição no desenvolvimento da compostagem de dejetos de suínos com maravalha In: CONGRESO ARGENTINO DE INGENIERÍA RURAL, 10.; MERCOSUR, 2., 2009, Rosário . Actas: el compromisso de la ingeniería rural con el desarrollo territorial. Rosário: Editorial de la Universidad Nacional de Rosario, 2009 Projeto/Plano de Ação: 03.06.092-02| Biblioteca(s): Embrapa Suínos e Aves. |
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| 8. | | GARCIA, A.; DIAS, W. P.; SILVA, J. F. V.; HIROMOTO, D.; PEREIRA, J. E. Dinamica de Heterodera glycines, em semeadura direta e convencional, em Primavera do Leste, MT. In: REUNIAO DE PESQUISA DE SOJA DA REGIAO CENTRAL DO BRASIL, 22., 2000, Cuiaba. Resumos... Londrina: Embrapa Soja, 2000. p.76. (Embrapa Soja. Documentos, 144).| Biblioteca(s): Embrapa Soja. |
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| 11. | | BONNAL, P.; XAVIER, J. H. V.; SANTOS, N. A. dos; SOUZA, G. L. C. de; ZOBY, J. L. F.; GASTAL, M. L.; PEREIRA, E. A.; PANIAGO JUNIOR, E.; SOUZA, J. B. de. O papel da rede de fazendas de referencia no enfoque de pesquisa - desenvolvimento: Projeto Silvania. Planaltina: EMBRAPA-CPAC, 1994. 31p. (EMBRAPA-CPAC. Documentos, 56).| Biblioteca(s): Embrapa Amazônia Ocidental; Embrapa Cerrados; Embrapa Florestas; Embrapa Meio-Norte; Embrapa Pantanal; Embrapa Semiárido; Embrapa Solos. |
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| 12. | | MELLO, B. L. B. de; SANTOS, C. de O.; DERESZ, F.; CHAMBELA NETO, A.; VIEIRA, R. A. M.; FERNANDES, A. M. Produção de leite em pasto de capim Tanzânia manejado sob pastoreio rotacionado. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 47., 2010, Salvador. Empreendedorismo e progresso científico na zootecnia brasileira: anais. Viçosa, MG: Sociedade Brasileira de Zootecnia, 2010. 3 p.| Biblioteca(s): Embrapa Gado de Leite. |
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| 13. | | BIANCHI, S. R.; MOREIRA, A.; SOUZA, G. B. de; NOGUEIRA, A. R. de A.; MENEZES, E. A. de; LEMOS, S. G. Potencial de uso da vinhaça no cultivo da alfafa em Latossolo Vermelho Amarelo e Neossolo Quartzarênico. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 45., 2008, Lavras, MG. Anais... Lavras: SBZ: UFLA, 2008.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 14. | | RAMALHO, A. R.; ROCHA, R. B.; SOUZA, F. de F.; VENEZIANO, W.; TEIXEIRA, A. L. Progresso genético da produtividade de café beneficiado com a seleçãode clones de cafeeiro Conilon. Revista Ciência Agronômica, v. 47, n. 3, p. 516-523, jul-set, 2016.| Biblioteca(s): Embrapa Rondônia. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
04/05/2021 |
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Data da última atualização: |
10/06/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
CHAGAS, P. A. M.; SCHNEIDER, R.; SANTOS, D. M. dos; OTUKA, A. J. G.; MENDONÇA, C. R.; CORREA, D. S. |
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Afiliação: |
DANIEL SOUZA CORREA, CNPDIA. |
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Título: |
Bilayered electrospun membranes composed of poly(lactic-acid)/natural rubber: A strategy against curcumin photodegradation for wound dressing application. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Reactive and Functional Polymers, v. 163, a. 104889, 2021. |
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Páginas: |
1 - 11 |
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ISSN: |
1381-5148 |
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DOI: |
https://doi.org/10.1016/j.reactfunctpolym.2021.104889 |
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Idioma: |
Inglês |
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Conteúdo: |
Curcumin is a natural phenolic compound renowned for its beneficial anti-carcinogenic, anti-oxidant, antibacterial and anti-inflammatory properties. More recently, this active compound has also demonstrated wound healing capability and antibacterial properties, which are essential prerequisites to treat skin injuries. However, the practical application of curcumin in wound-healing dressing is limited by its susceptibility to photodegradation when exposed to artificial or natural sunlight. To maintain the pharmacological and antibacterial properties of curcumin and prevent its photodegradation, we have developed a bilayered asymmetric membrane for wound healing application composed of two layers of electrospun fibers. The bottom layer is composed of a biodegradable blend of poly(lactic acid)(PLA)/natural rubber(NR) microfibers containing curcumin in the bulk. In contrast, the top layer is composed solely of PLA nanofibers to simultaneously protect curcumin against photodegradation and avoid bacterial penetration. Scanning electron microscopy, Fourier transform infrared spectroscopy, UV–Vis spectroscopy, thermal analyses, contact angle measurements and antibacterial assay were employed to investigate the properties of the membranes. Our results demonstrated the top layer of PLA was crucial to prevent the photodegradation of curcumin contained in the PLA/NR microfibers bottom layer and also avoided the penetration of bacteria for 10 days. Additionally, the PLA/NR microfibers showed strong antibacterial activity against Staphylococcus aureus. Our results demonstrated the potential of bilayered nano/microfibrous membranes to be applied in the design of wound dressings containing active compounds susceptible to photodegradation MenosCurcumin is a natural phenolic compound renowned for its beneficial anti-carcinogenic, anti-oxidant, antibacterial and anti-inflammatory properties. More recently, this active compound has also demonstrated wound healing capability and antibacterial properties, which are essential prerequisites to treat skin injuries. However, the practical application of curcumin in wound-healing dressing is limited by its susceptibility to photodegradation when exposed to artificial or natural sunlight. To maintain the pharmacological and antibacterial properties of curcumin and prevent its photodegradation, we have developed a bilayered asymmetric membrane for wound healing application composed of two layers of electrospun fibers. The bottom layer is composed of a biodegradable blend of poly(lactic acid)(PLA)/natural rubber(NR) microfibers containing curcumin in the bulk. In contrast, the top layer is composed solely of PLA nanofibers to simultaneously protect curcumin against photodegradation and avoid bacterial penetration. Scanning electron microscopy, Fourier transform infrared spectroscopy, UV–Vis spectroscopy, thermal analyses, contact angle measurements and antibacterial assay were employed to investigate the properties of the membranes. Our results demonstrated the top layer of PLA was crucial to prevent the photodegradation of curcumin contained in the PLA/NR microfibers bottom layer and also avoided the penetration of bacteria for 10 days. Additionally, the PLA/NR microfibers sh... Mostrar Tudo |
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Palavras-Chave: |
Bilayered membrane; Electrospinning; Polymer nanofibers; Wound dressing. |
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Categoria do assunto: |
-- |
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Marc: |
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024 7 $ahttps://doi.org/10.1016/j.reactfunctpolym.2021.104889$2DOI
100 1 $aCHAGAS, P. A. M.
245 $aBilayered electrospun membranes composed of poly(lactic-acid)/natural rubber$bA strategy against curcumin photodegradation for wound dressing application.$h[electronic resource]
260 $c2021
300 $a1 - 11
520 $aCurcumin is a natural phenolic compound renowned for its beneficial anti-carcinogenic, anti-oxidant, antibacterial and anti-inflammatory properties. More recently, this active compound has also demonstrated wound healing capability and antibacterial properties, which are essential prerequisites to treat skin injuries. However, the practical application of curcumin in wound-healing dressing is limited by its susceptibility to photodegradation when exposed to artificial or natural sunlight. To maintain the pharmacological and antibacterial properties of curcumin and prevent its photodegradation, we have developed a bilayered asymmetric membrane for wound healing application composed of two layers of electrospun fibers. The bottom layer is composed of a biodegradable blend of poly(lactic acid)(PLA)/natural rubber(NR) microfibers containing curcumin in the bulk. In contrast, the top layer is composed solely of PLA nanofibers to simultaneously protect curcumin against photodegradation and avoid bacterial penetration. Scanning electron microscopy, Fourier transform infrared spectroscopy, UV–Vis spectroscopy, thermal analyses, contact angle measurements and antibacterial assay were employed to investigate the properties of the membranes. Our results demonstrated the top layer of PLA was crucial to prevent the photodegradation of curcumin contained in the PLA/NR microfibers bottom layer and also avoided the penetration of bacteria for 10 days. Additionally, the PLA/NR microfibers showed strong antibacterial activity against Staphylococcus aureus. Our results demonstrated the potential of bilayered nano/microfibrous membranes to be applied in the design of wound dressings containing active compounds susceptible to photodegradation
653 $aBilayered membrane
653 $aElectrospinning
653 $aPolymer nanofibers
653 $aWound dressing
700 1 $aSCHNEIDER, R.
700 1 $aSANTOS, D. M. dos
700 1 $aOTUKA, A. J. G.
700 1 $aMENDONÇA, C. R.
700 1 $aCORREA, D. S.
773 $tReactive and Functional Polymers$gv. 163, a. 104889, 2021.
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