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Registro Completo
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
14/01/2021 |
Data da última atualização: |
11/03/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
QUITETE, F. T.; SANTOS, G. M. A.; RIBEIRO, L. de O.; COSTA, C. A. da; FREITAS, S. P.; MATTA, V. M. da; DELEPRANE, J. B. |
Afiliação: |
Fernanda Torres Quitete, UERJ; Giulia Medeiros Almeida Santos, UERJ; Leilson de Oliveira Ribeiro, UERJ; Cristiane Aguiar da Costa; Suely Pereira Freitas, UFRJ; VIRGINIA MARTINS DA MATTA, CTAA; Julio Beltrame Daleprane, UERJ. |
Título: |
Phenolic-rich smoothie consumption ameliorates non-alcoholic fatty liver disease in obesity mice by increasing antioxidant response. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Chemico-Biological Interactions, v. 336, 109369, 2021. |
DOI: |
https://doi.org/10.1016/j.cbi.2021.109369 |
Idioma: |
Inglês |
Notas: |
Pre-proof in press. |
Conteúdo: |
Consumption of foods rich in phenolic compounds can be beneficial for health. This study aimed to examine whether the consumption of a phenolic-rich smoothie, based on jucara, strawberry and banana, ameliorates metabolic status and liver damage of diet-induced obese mice. Forty male C57BL/6J mice were assigned into four groups (n = 10) and fed control diet with free access to water (C) or phenolic-rich smoothie (C-S), or fed high-fat diet with free access to water (HF) or phenolic-rich smoothie (HF-S) for five weeks. HF and HF-S groups had higher body weight gains than the C group, however the HF had a greater adipose index, higher plasma levels of glucose, insulin and leptin, as well as higher plasma and hepatic steatosis than C, C-S and HF-S groups. The liver oxidative stress markers were reduced in C-S and HF-S groups and the activity of catalase and glutathione peroxidase were higher compared with their counterparts. The present study suggests that regular consumption of a phenolic-rich smoothie improves the liver antioxidant status, prevents metabolic disorders and ameliorates non-alcoholic fatty liver disease caused by high-fat diet consumption. |
Palavras-Chave: |
Antioxidant capacity; Liver steatosis. |
Thesaurus NAL: |
Adipose tissue; Antioxidants; Food technology; Obesity; Phenolic compounds; Tropical and subtropical fruits. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02165naa a2200313 a 4500 001 2129339 005 2021-03-11 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.cbi.2021.109369$2DOI 100 1 $aQUITETE, F. T. 245 $aPhenolic-rich smoothie consumption ameliorates non-alcoholic fatty liver disease in obesity mice by increasing antioxidant response.$h[electronic resource] 260 $c2021 500 $aPre-proof in press. 520 $aConsumption of foods rich in phenolic compounds can be beneficial for health. This study aimed to examine whether the consumption of a phenolic-rich smoothie, based on jucara, strawberry and banana, ameliorates metabolic status and liver damage of diet-induced obese mice. Forty male C57BL/6J mice were assigned into four groups (n = 10) and fed control diet with free access to water (C) or phenolic-rich smoothie (C-S), or fed high-fat diet with free access to water (HF) or phenolic-rich smoothie (HF-S) for five weeks. HF and HF-S groups had higher body weight gains than the C group, however the HF had a greater adipose index, higher plasma levels of glucose, insulin and leptin, as well as higher plasma and hepatic steatosis than C, C-S and HF-S groups. The liver oxidative stress markers were reduced in C-S and HF-S groups and the activity of catalase and glutathione peroxidase were higher compared with their counterparts. The present study suggests that regular consumption of a phenolic-rich smoothie improves the liver antioxidant status, prevents metabolic disorders and ameliorates non-alcoholic fatty liver disease caused by high-fat diet consumption. 650 $aAdipose tissue 650 $aAntioxidants 650 $aFood technology 650 $aObesity 650 $aPhenolic compounds 650 $aTropical and subtropical fruits 653 $aAntioxidant capacity 653 $aLiver steatosis 700 1 $aSANTOS, G. M. A. 700 1 $aRIBEIRO, L. de O. 700 1 $aCOSTA, C. A. da 700 1 $aFREITAS, S. P. 700 1 $aMATTA, V. M. da 700 1 $aDELEPRANE, J. B. 773 $tChemico-Biological Interactions$gv. 336, 109369, 2021.
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