| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Gado de Leite. |
|
Data corrente: |
05/02/2013 |
|
Data da última atualização: |
08/02/2024 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
OTENIO, C. C. M.; FONSECA, I.; MARTINS, M. F.; RIBEIRO, L. C.; ASSIS, N. M. S. P.; FERREIRA, A. P.; RIBEIRO, R. A. |
|
Afiliação: |
C. C. M. OTENIO, UFJF; I. FONSECA, UFV; MARTA FONSECA MARTINS, CNPGL; L. C. RIBEIRO, UFV; N. M. S. P. ASSIS, UFJF; A. P. FERREIRA, UFJF; R. A. RIBEIRO, UFJF. |
|
Título: |
Expression of IL-1B, IL-6, TNF-a and iNOS in pregnant women with periodontal disease. |
|
Ano de publicação: |
2012 |
|
Fonte/Imprenta: |
Genetics and Molecular Research, v. 11, n. 4, p. 4468-4478, 2012. |
|
DOI: |
https://doi.org/10.4238/2012.september.20.3 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Periodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison with non-pregnant women with and without periodontal disease since studies have suggested a relationship between periodontitis and the expression levels of these genes. The women in the sample were distributed into four groups: pregnant and non-pregnant women, with or without periodontal disease, a total of 32 women. The periodontal condition was evaluated according to the probing depth, clinical attachment level and bleeding on probing. Analysis of gene expression was performed by real-time PCR. Comparisons were made of the level of gene expression among the four groups. Expression of IL-1β in the non-pregnant women with periodontal disease was 12.6 times higher than in the non-pregnant women without periodontal disease (P < 0.01), while expression of TNF-α in the non-pregnant women without periodontal disease was 3.5 times higher than in the pregnant women with periodontal disease (P < 0.05). Despite these differences, our overall findings indicate no differences in the expression levels of the cytokines IL-1β, IL-6, TNF-α, and iNOS in pregnant women with and without periodontal disease in comparison with expression of the same genes in non-pregnant women with and without periodontal disease, suggesting that periodontal disease is not influenced by pregnancy. MenosPeriodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison with non-pregnant women with and without periodontal disease since studies have suggested a relationship between periodontitis and the expression levels of these genes. The women in the sample were distributed into four groups: pregnant and non-pregnant women, with or without periodontal disease, a total of 32 women. The periodontal condition was evaluated according to the probing depth, clinical attachment level and bleeding on probing. Analysis of gene expression was performed by real-time PCR. Comparisons were made of the level of gene expression among the four groups. Expression of IL-1β in the non-pregnant women with periodontal disease was 12.6 times higher than in the non-pregnant women without periodontal disease (P < 0.01), while expression of TNF-α in the non-pregnant women without periodontal disease was 3.5 times higher than in the pregnant women with periodontal disease (P < 0.05). Despite these differences, our overall findings indicate no differences in the expression levels of the cytokines IL-1β, IL-6, TNF-α, and iNOS in pregnant women with and without periodontal disease... Mostrar Tudo |
|
Palavras-Chave: |
Gengiva; Periodonto. |
|
Categoria do assunto: |
H Saúde e Patologia |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/948391/1/Expression-of-IL-1B-IL-6-TNF-a-and-iNOS-in-pregnant.pdf
|
|
Marc: |
LEADER 02389naa a2200229 a 4500
001 1948391
005 2024-02-08
008 2012 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.4238/2012.september.20.3$2DOI
100 1 $aOTENIO, C. C. M.
245 $aExpression of IL-1B, IL-6, TNF-a and iNOS in pregnant women with periodontal disease.$h[electronic resource]
260 $c2012
520 $aPeriodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison with non-pregnant women with and without periodontal disease since studies have suggested a relationship between periodontitis and the expression levels of these genes. The women in the sample were distributed into four groups: pregnant and non-pregnant women, with or without periodontal disease, a total of 32 women. The periodontal condition was evaluated according to the probing depth, clinical attachment level and bleeding on probing. Analysis of gene expression was performed by real-time PCR. Comparisons were made of the level of gene expression among the four groups. Expression of IL-1β in the non-pregnant women with periodontal disease was 12.6 times higher than in the non-pregnant women without periodontal disease (P < 0.01), while expression of TNF-α in the non-pregnant women without periodontal disease was 3.5 times higher than in the pregnant women with periodontal disease (P < 0.05). Despite these differences, our overall findings indicate no differences in the expression levels of the cytokines IL-1β, IL-6, TNF-α, and iNOS in pregnant women with and without periodontal disease in comparison with expression of the same genes in non-pregnant women with and without periodontal disease, suggesting that periodontal disease is not influenced by pregnancy.
653 $aGengiva
653 $aPeriodonto
700 1 $aFONSECA, I.
700 1 $aMARTINS, M. F.
700 1 $aRIBEIRO, L. C.
700 1 $aASSIS, N. M. S. P.
700 1 $aFERREIRA, A. P.
700 1 $aRIBEIRO, R. A.
773 $tGenetics and Molecular Research$gv. 11, n. 4, p. 4468-4478, 2012.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
01/12/2014 |
|
Data da última atualização: |
13/03/2023 |
|
Tipo da produção científica: |
Artigo em Anais de Congresso |
|
Autoria: |
MURAD, A. M.; CUNHA, N.; LACORTE, C. C.; COELHO, M. C. F.; VIANNA, G. R.; RECH FILHO, E. L. |
|
Afiliação: |
ANDRE MELRO MURAD, CENARGEN; NICOLAU CUNHA; CRISTIANO CASTRO LACORTE, CENARGEN; MARLY CATARINA FELIPE COELHO, CENARGEN; GIOVANNI RODRIGUES VIANNA, CENARGEN; ELIBIO LEOPOLDO RECH FILHO, CENARGEN. |
|
Título: |
Expression, purification and analysis of the anti-HIV Cyanovirin-N produced in transgenic soybeans seeds. |
|
Ano de publicação: |
2014 |
|
Fonte/Imprenta: |
BMC Proceedings, v.8, suppl, P.105, 2014. (Open access) |
|
Idioma: |
Inglês |
|
Notas: |
Edição do Congress of the Brazilian Biotechnology Society, Florianópolis, 2013. |
|
Palavras-Chave: |
Anti-HIV; Soja transgênica; Soybeans seeds. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/112706/1/1753-6561-8-S4-P105.pdf
|
|
Marc: |
LEADER 00717nam a2200205 a 4500
001 2001202
005 2023-03-13
008 2014 bl uuuu u00u1 u #d
100 1 $aMURAD, A. M.
245 $aExpression, purification and analysis of the anti-HIV Cyanovirin-N produced in transgenic soybeans seeds.$h[electronic resource]
260 $aBMC Proceedings, v.8, suppl, P.105, 2014. (Open access)$c2014
500 $aEdição do Congress of the Brazilian Biotechnology Society, Florianópolis, 2013.
653 $aAnti-HIV
653 $aSoja transgênica
653 $aSoybeans seeds
700 1 $aCUNHA, N.
700 1 $aLACORTE, C. C.
700 1 $aCOELHO, M. C. F.
700 1 $aVIANNA, G. R.
700 1 $aRECH FILHO, E. L.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
