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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
03/10/2016 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
LASKOSKI, L. M.; LOCATELLI-DITTRICH, R.; SOUSA, R. S.; BRUM, J. S.; CRISTO, T. G.; MONTIANI-FERREIRA, F.; BELTRAME, O. C.; VALADÃO, C. A. A. |
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Afiliação: |
LUCIANE M. LASKOSKI, UFPR; ROSANGELA LOCATELLI-DITTRICH, UFPR; RENATO S. SOUSA, UFPR; JULIANA S. BRUM, UFPR; THIERRY G. CRISTO, CAV/UDESC; FABIANO MONTIANI-FERREIRA, UFPR; OLAIR C. BELTRAME, UFPR; CARLOS A. A. VALADÃO, UNESP. |
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Título: |
Laminar lesions in horses with systemic oxidative stress, committed by experimentally induced or naturally occurring gastrointestinal disorders. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 8, p. 694-700, ago. 2016. |
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Idioma: |
Inglês |
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Conteúdo: |
Laminitis in horses can be associated with lesions in multiple organs secondary to sepsis. Twenty-one horses suffering from gastrointestinal disorders were used in the experiment; 7 horses with experimentally induced endotoxemia and intestinal ischaemia, and 14 horses suffering from naturally occurring colic syndrome. Tissue samples of lungs, liver, heart, brain, cerebellum and hoof laminar tissue were collected for histopathological and oxidative stress evaluation using nitrotyrosine and superoxide dismutase (SOD2) immunostaining. The horses were divided into two groups: the non-oxidative lesions group (NOLG), with 7 horses showing weak immunostaining in lungs, liver and kidney, and the oxidative lesions group (OLG), with 14 horses showing immunostaining indicating systemic oxidative stress in multiple organs. The horses from OLG showed increase of laminar lesions and SOD2 immunostaining in multiple organs when compared to the horses from the NOLG. No differences were found ln regard to laminar immunostaining by nitrotyrosine and SOD2 between experimental groups. It was concluded that systemic oxidative stress can be associated with the development of laminar lesions, and that the laminar tissue does not respond to oxidative stress with increase of SOD as occurs in other organs. |
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Palavras-Chave: |
Laminite; Nitrotirosina; Nitrotyrosine; Peroxinitrito; Peroxynitrite; Sepse; Superóxido dismutase. |
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Thesagro: |
Eqüino. |
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Thesaurus Nal: |
Horses; Laminitis; Superoxide dismutase. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/148184/1/Laminar-lesions-in-horses.pdf
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Marc: |
LEADER 02301naa a2200337 a 4500
001 2053968
005 2017-12-29
008 2016 bl uuuu u00u1 u #d
100 1 $aLASKOSKI, L. M.
245 $aLaminar lesions in horses with systemic oxidative stress, committed by experimentally induced or naturally occurring gastrointestinal disorders.
260 $c2016
520 $aLaminitis in horses can be associated with lesions in multiple organs secondary to sepsis. Twenty-one horses suffering from gastrointestinal disorders were used in the experiment; 7 horses with experimentally induced endotoxemia and intestinal ischaemia, and 14 horses suffering from naturally occurring colic syndrome. Tissue samples of lungs, liver, heart, brain, cerebellum and hoof laminar tissue were collected for histopathological and oxidative stress evaluation using nitrotyrosine and superoxide dismutase (SOD2) immunostaining. The horses were divided into two groups: the non-oxidative lesions group (NOLG), with 7 horses showing weak immunostaining in lungs, liver and kidney, and the oxidative lesions group (OLG), with 14 horses showing immunostaining indicating systemic oxidative stress in multiple organs. The horses from OLG showed increase of laminar lesions and SOD2 immunostaining in multiple organs when compared to the horses from the NOLG. No differences were found ln regard to laminar immunostaining by nitrotyrosine and SOD2 between experimental groups. It was concluded that systemic oxidative stress can be associated with the development of laminar lesions, and that the laminar tissue does not respond to oxidative stress with increase of SOD as occurs in other organs.
650 $aHorses
650 $aLaminitis
650 $aSuperoxide dismutase
650 $aEqüino
653 $aLaminite
653 $aNitrotirosina
653 $aNitrotyrosine
653 $aPeroxinitrito
653 $aPeroxynitrite
653 $aSepse
653 $aSuperóxido dismutase
700 1 $aLOCATELLI-DITTRICH, R.
700 1 $aSOUSA, R. S.
700 1 $aBRUM, J. S.
700 1 $aCRISTO, T. G.
700 1 $aMONTIANI-FERREIRA, F.
700 1 $aBELTRAME, O. C.
700 1 $aVALADÃO, C. A. A.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 36, n. 8, p. 694-700, ago. 2016.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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| 2. |  | NUNES, M. R.; VAZ, C. M. P.; DENARDIN, J. E.; VAN ES, H. M.; LIBARDI, P. L.; SILVA, A. P. da. Physicochemical and structural properties of an oxisol under the addition of straw and lime. Soil Science Society of America Journal, Madison, v. 81, n. 6, p. 1328-1339, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação; Embrapa Trigo. |
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| 3. | | NUNES, M. R.; SILVA, A. P.; DENARDIN, J. E.; GIAROLA, N. F. B.; VAZ, C. M. P.; van ES, H. M.; SILVA, A. R. Soil chemical management drives structural degradation of Oxisols under a no-till cropping system. In: Soil Research, v. 58, n. 8, p. 819-831, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
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