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| Registros recuperados : 27 | |
| 8. |  | VIANA, B. F.; SILVA, F. O. da; KLEINERT, A. de M. P. A flora apícola de uma área restrita de dunas litorâneas, Abaeté, Salvador, Bahia. Revista Brasileira de Botânica, v. 29, n. 1, p. 13-25, 2006.| Biblioteca(s): Embrapa Semiárido. |
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| 11. | | VASCONCELOS, G. A. de; VIANA, B. L.; LIRA, C. C.; MENOR, T. R. F. de L.; ALBUQUERQUE, G. P. de; MELO, P. M. C. de. Comportamento ingestivo de ovinos em pastagens de Pennisetum sp. em diferentes estações do ano na Zona da Mata Pernambucana. In: CONGRESSO NORDESTINO DE PRODUÇÃO ANIMAL, 6.; SIMPÓSIO NORDESTINO DE ALIMENTAÇÃO DE RUMINANTES, 7.; FÓRUM DE COORDENADORES DE PÓS GRADUAÇÃO EM PRODUÇÃO ANIMAL DO NORDESTE, 1.; FÓRUM DE AGROECOLOGIA RO RIO GRANDE DO NORTE, 1., 2010, Mossoró. Anais... Mossoró: Sociedade Nordestina de Producao Animal; UFERSA, 2010. 4 f. 1 CD-ROM.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 12. | | PARENTE, H. N.; SILVA, D. S. da; ANDRADE, A. P. de; LEITE, M. L. de M. V.; VIANA, B. L.; TORRES, A. S.; SANTOS, E. G. dos. Influência da adubação nitrogenada sobre o crescimento inicial e composição química e mineral da maniçoba (Manihot sp.). Revista Científica de Produção Animal, v. 9, n. 2, p. 102-110, 2007.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 14. | | VIANA, B. L.; MELO, A. C. L. de; GUIM, A.; LIRA, M. de A.; DUBEUX JÚNIOR, J. C. B.; SANTOS, M. V. F. dos; CUNHA, M. V. da. Morphological characteristics and proportion of leaf blade tissues of elephant grass clones under sheep grazing. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 53, n. 11, p. 1268-1275, Nov. 2018. Título em português: Características morfológicas e proporção de tecidos da lâmina foliar em clones de capim-elefante sob pastejo de ovelhas.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 16. | | VIANA, B. L.; MELLO, A. C. L. de; LIRA, M. de A.; DUBEUX JUNIOR, J. C. B.; SANTOS, M. V. F. dos; CUNHA, M. V. da; FERREIRA, G. D. G. Repetibilidade e respostas de características morfofisiológicas e produtivas de capim-elefante de porte baixo sob pastejo. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 44, n. 12, p. 1731-1738, dez. 2009 Título em inglês: Repeatability of morphophysiological and yield characteristics and response of dwarf elephant grass under grazing.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 17. | | FADEL, L.; VIANA, B. R.; FEITOSA, M. L. T.; ERCOLIN, A. C. M.; ROBALLO, K. C. S.; CASALS, J. B.; PIERI, N. C. G.; MEIRELLES, F. V.; MARTINS, D. dos S.; MIGLINO, M. A.; AMBRÓSIO, C. E. Protocols for obtainment and isolation of two mesenchymal stem cell sources in sheep. Acta Cirurgica Brasileira, v. 26, n. 4, p. 267-273, 2011.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 18. | | SILVA, C.; FREITAS, B.; BAUERMANN, S.; KLEINERT, A.; IMPERATRIZ-FONSECA, V.; MAUES, M. M.; ALBUQUERQUE, P.; NOVAIS, J.; TOLEDO, V.; BLOCHTEIN, B.; SARMENTO, E.; KRUG, C.; CURE, J.; ESTEVES, V.; MENDONÇA, C.; VIANA, B.; SANTOS, F.; SANTOS, I.; SARAIVA, A. Bee flora and pollen grains study for the Online Pollen Catalogue Network: basis for plantpollinator interactions research. In: ANNUAL MEETING OF THE ASSOCIATION FOR TROPICAL BIOLOGY AND CONSERVATION, 53., 2016, Montpellier. Tropical ecology and society: reconciling conservation and sustainable use of biodiversity: program & abstracts. [S.l.]: ATBC, 2016. p. 409.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 19. | | SILVA, C.; FREITAS, B.; BAUERMANN, S.; KLEINERT, A.; IMPERATRIZ-FONSECA, V.; MAUES, M. M.; ALBUQUERQUE, P.; NOVAIS, J.; TOLEDO, V.; BLOCHTEIN, B.; SARMENTO, E.; KRUG, C.; CURE, J.; ESTEVES, V.; MENDONÇA, C.; VIANA, B.; SANTOS, F.; SANTOS, I.; SARAIVA, A. Bee flora and pollen grains study for the Online Pollen Catalogue Network: basis for plantpollinator interactions research. In: ANNUAL MEETING OF THE ASSOCIATION FOR TROPICAL BIOLOGY AND CONSERVATION, 53., 2016, Montpellier. Tropical ecology and society: reconciling conservation and sustainable use of biodiversity: program & abstracts. [S.l.]: ATBC, 2016. p. 409.| Biblioteca(s): Embrapa Amazônia Oriental. |
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| 20. | | DIKS, L. V.; VIANA, B.; BOMMARCO, R.; BROSI, B.; ARIZMENDI, M. DEL C.; CUNNINGHAM, S. A.; GALETTO, L.; HILL, R.; LOPES, A. V.; PIRES, C. S. S.; TAKI, H.; POTTS, S. G. Ten policies for pollinators: what governments can do to safeguard pollination services. Science, v.354, n. 6315, p.975-976.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| Registros recuperados : 27 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agroindústria de Alimentos. Para informações adicionais entre em contato com ctaa.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
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Data corrente: |
29/12/2020 |
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Data da última atualização: |
04/03/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
MONTENEGRO, J.; SANTOS, L. S. dos; SOUZA, R. G. G. de; LIMA, L. G. B.; MATTOS, D. S.; VIANA, B. P. P. B.; BASTOS, A. C. S. da F.; MUZZI, L.; CONTE-JÚNIOR, C. A.; GIMBA, E. R. P.; FREITAS-SILVA, O. |
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Afiliação: |
Júlia Montenegro, Universidade Federal do Estado do Rio de Janeiro, UNIRIO; Lauriza Silva dos Santos, Universidade Federal do Estado do Rio de Janeiro, UNIRIO; Rodrigo Gonçalves Gusmão de Souza, UNIRIO; Larissa Gabrielly Barbosa Lima, Universidade Federal do Estado do Rio de Janeiro, UNIRIO; Daniella Santos Mattos, Instituto Nacional do Câncer, INCa; Bruna Prunes Pena Baroni Viana, Instituto Nacional do Câncer, INCa; Ana Clara Santos da Fonseca Bastos, Instituto Nacional do Câncer, INCa; Leda Muzzi, Universidade Federal Fluminense, UFF; Carlos Adam Conte-Júnior, Universidade Federal Fluminense, UFF; Etel Rodrigues Pereira Gimba, Instituto Nacional do Câncer, INCa; Universidade Federal Fluminense, UFF; OTNIEL FREITAS SILVA, CTAA. |
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Título: |
Bioactive compounds, antioxidant activity and antiproliferative effects in prostate cancer cells of green and roasted coffee extracts obtained by microwave-assisted extraction (MAE). |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Food Research International, v. 140, 110014, 2021. |
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DOI: |
https://doi.org/10.1016/j.foodres.2020.110014 |
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Idioma: |
Inglês |
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Notas: |
Epub 2020 Dec 15. |
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Conteúdo: |
Coffee consumption has been investigated as a protective factor against prostate cancer. Coffee may be related to prostate cancer risk reduction due to its phytochemical compounds, such as caffeine, chlorogenic acids, and trigonelline. The roasting process affects the content of the phytochemicals and undesired compounds can be formed. Microwave-assisted extraction is an alternative to conventional extraction techniques since it preserves more bioactive compounds. Therefore, this study aimed to evaluate the phytochemical composition and the putative preventive effects in prostate cancer development of coffee beans submitted to four different coffee- roasting degrees extracted using microwave-assisted extraction. Coffea arabica green beans (1) were roasted into light (2), medium (3) and dark (4) and these four coffee samples were submitted to microwave-assisted extraction. The antioxidant capacity of these samples was evaluated by five different methods. Caffeine, chlorogenic acid and caffeic acid were measured through HPLC. Samples were tested against PC-3 and DU-145 metastatic prostate cancer cell lines regarding their effects on cell viability, cell cycle progression and apoptotic cell death. We found that green and light roasted coffee extracts had the highest antioxidant activity. Caffeine content was not affected by roasting, chlorogenic acid was degraded due to the temperature, and caffeic acid increased in light roasted and decreased in medium and dark roasted. Green and light roasted coffee extracts promoted higher inhibition of cell viability, caused greater cell cycle arrest in S and G2/M and induced apoptosis more compared to medium and dark roasted coffee extracts and the control samples. Coffee extracts were more effective against DU-145 than in PC-3 cells. Our data provide initial evidence that among the four tested samples, the consumption of green and light coffee extracts contributes to inhibit prostate cancer tumor progression features, potentially preventing aspects related to advanced prostate cancer subtypes. MenosCoffee consumption has been investigated as a protective factor against prostate cancer. Coffee may be related to prostate cancer risk reduction due to its phytochemical compounds, such as caffeine, chlorogenic acids, and trigonelline. The roasting process affects the content of the phytochemicals and undesired compounds can be formed. Microwave-assisted extraction is an alternative to conventional extraction techniques since it preserves more bioactive compounds. Therefore, this study aimed to evaluate the phytochemical composition and the putative preventive effects in prostate cancer development of coffee beans submitted to four different coffee- roasting degrees extracted using microwave-assisted extraction. Coffea arabica green beans (1) were roasted into light (2), medium (3) and dark (4) and these four coffee samples were submitted to microwave-assisted extraction. The antioxidant capacity of these samples was evaluated by five different methods. Caffeine, chlorogenic acid and caffeic acid were measured through HPLC. Samples were tested against PC-3 and DU-145 metastatic prostate cancer cell lines regarding their effects on cell viability, cell cycle progression and apoptotic cell death. We found that green and light roasted coffee extracts had the highest antioxidant activity. Caffeine content was not affected by roasting, chlorogenic acid was degraded due to the temperature, and caffeic acid increased in light roasted and decreased in medium and dark roasted. Green ... Mostrar Tudo |
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Palavras-Chave: |
Ácidos clorogênicos; Câncer de próstata; Chlorogenic acids; DU-145; MAE; PC-3; Prostate cancer; Roasting degree. |
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Thesagro: |
Café; Câncer; Torrefação. |
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Thesaurus NAL: |
Coffee (beverage); Food technology. |
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Categoria do assunto: |
Q Alimentos e Nutrição Humana |
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Marc: |
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001 2128795
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008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.foodres.2020.110014$2DOI
100 1 $aMONTENEGRO, J.
245 $aBioactive compounds, antioxidant activity and antiproliferative effects in prostate cancer cells of green and roasted coffee extracts obtained by microwave-assisted extraction (MAE).$h[electronic resource]
260 $c2021
500 $aEpub 2020 Dec 15.
520 $aCoffee consumption has been investigated as a protective factor against prostate cancer. Coffee may be related to prostate cancer risk reduction due to its phytochemical compounds, such as caffeine, chlorogenic acids, and trigonelline. The roasting process affects the content of the phytochemicals and undesired compounds can be formed. Microwave-assisted extraction is an alternative to conventional extraction techniques since it preserves more bioactive compounds. Therefore, this study aimed to evaluate the phytochemical composition and the putative preventive effects in prostate cancer development of coffee beans submitted to four different coffee- roasting degrees extracted using microwave-assisted extraction. Coffea arabica green beans (1) were roasted into light (2), medium (3) and dark (4) and these four coffee samples were submitted to microwave-assisted extraction. The antioxidant capacity of these samples was evaluated by five different methods. Caffeine, chlorogenic acid and caffeic acid were measured through HPLC. Samples were tested against PC-3 and DU-145 metastatic prostate cancer cell lines regarding their effects on cell viability, cell cycle progression and apoptotic cell death. We found that green and light roasted coffee extracts had the highest antioxidant activity. Caffeine content was not affected by roasting, chlorogenic acid was degraded due to the temperature, and caffeic acid increased in light roasted and decreased in medium and dark roasted. Green and light roasted coffee extracts promoted higher inhibition of cell viability, caused greater cell cycle arrest in S and G2/M and induced apoptosis more compared to medium and dark roasted coffee extracts and the control samples. Coffee extracts were more effective against DU-145 than in PC-3 cells. Our data provide initial evidence that among the four tested samples, the consumption of green and light coffee extracts contributes to inhibit prostate cancer tumor progression features, potentially preventing aspects related to advanced prostate cancer subtypes.
650 $aCoffee (beverage)
650 $aFood technology
650 $aCafé
650 $aCâncer
650 $aTorrefação
653 $aÁcidos clorogênicos
653 $aCâncer de próstata
653 $aChlorogenic acids
653 $aDU-145
653 $aMAE
653 $aPC-3
653 $aProstate cancer
653 $aRoasting degree
700 1 $aSANTOS, L. S. dos
700 1 $aSOUZA, R. G. G. de
700 1 $aLIMA, L. G. B.
700 1 $aMATTOS, D. S.
700 1 $aVIANA, B. P. P. B.
700 1 $aBASTOS, A. C. S. da F.
700 1 $aMUZZI, L.
700 1 $aCONTE-JÚNIOR, C. A.
700 1 $aGIMBA, E. R. P.
700 1 $aFREITAS-SILVA, O.
773 $tFood Research International$gv. 140, 110014, 2021.
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