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| Registros recuperados : 20 | |
| 1. |  | SILVA, H. T.; COSTA, C. N.; LOPES, P. S.; VERONEZE, R.; SILVA, F. F. e. Parâmetros genéticos para Stayabilityem bovinos da raça holandesa no Brasil. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 14., 2021, Santa Catarina. Passado, presente e futuro: anais. Santa Catarina: Sociedade Brasileira de Melhoramento Animal, 2021.| Biblioteca(s): Embrapa Gado de Leite. |
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| 2. | | VERNEQUE, R. da S.; VERONEZE, R.; PANETTO, J. C. do C.; SILVA, M. V. G. B.; TORAL, F. L. B. A contribuição do melhoramento animal para a pecuária de leite. In: VILELA, D.; FERREIRA, R. de P.; FERNANDES, E. N.; JUNTOLLI, F. V. (Ed.). Pecuária de leite no Brasil: cenários e avanços tecnológicos. Brasília, DF: Embrapa, 2016. p. 255-264.| Biblioteca(s): Embrapa Gado de Leite. |
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| 3. | | CARRARA, E. R.; LOPES, P. S.; VERONEZE, R.; PEREIRA, R. J.; ZADRA, L. E. F.; PEIXOTO, M. G. C. D. Assessment of runs of homozygosity, heterozygosity-rich regions and genomic inbreeding estimates in a subpopulation of Guzerá (Bos indicus) dual-purpose cattle. Journal of Animal Breeding and Genetics, v. 141, n. 2, p. 207-219, 2024.| Biblioteca(s): Embrapa Gado de Leite. |
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| 4. | | SILVA, H. T.; LOPES, P. S.; CARVALHEIRA, J.; SILVA, D. A.; SILVA, A. A.; SILVA, F. F.; VERONEZE, R.; THOMPSON, G.; COSTA, C. N. Autoregressive model for genetic evaluation of longitudinal reproductive traits in Brazilian Holstein cattle. Reproduction in Domestic Animals, v. 56, n. 3, p. 391-399, 2021.| Biblioteca(s): Embrapa Gado de Leite. |
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| 5. | | SILVA, D. A.; COSTA, C. N.; SILVA, A. A.; SILVA, H. T.; LOPES, P. S.; SILVA, F. F.; VERONEZE, R.; THOMPSON, G.; AGUILAR, I.; CARVALHEIRA, J. Autoregressive and random regression test-day models for multiple lactations in genetic evaluation of Brazilian Holstein cattle. Journal of Animal Breeding and Genetics, v. 137, n. 3, p. 305-315, 2020.| Biblioteca(s): Embrapa Gado de Leite. |
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| 6. | | SILVA, H. T.; LOPES, P. S.; COSTA, C. N.; SILVA, A. A.; SILVA, D. A.; SILVA, F. F.; VERONEZE, R.; THOMPSON, G.; CARVALHEIRA, J. Autoregressive single-step model for genomic evaluation of longitudinal reproductive traits in portuguese holstein cattle. Journal of Animal Breeding and Genetics, v. 138, n. 3, p. 349-359, 2021.| Biblioteca(s): Embrapa Gado de Leite. |
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| 7. | | DIANA, T. F.; CALDERANO, A. A.; ROSTAGNO, H. S.; MARQUES, M. R. de L.; TAVERNARI, F. de C.; VERONEZE, R.; ALBINO, L. F. T. Apparent calcium retention and digestibility coefficients of limestone with different particle sizes in laying hens. Scientia Agricola, v. 80, n. e20210258, 2023.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 8. | | SILVA, D. A.; LOPES, P. S.; COSTA, C. N.; SILVA, A. A.; SILVA, H. T.; SILVA, F. F.; VERONEZE, R.; THOMPSON, G.; CARVALHEIRA, J. Genotype by environment interaction for Holstein cattle populations using autoregressive and within- and across-countrymulti-trait reaction norms test-day models. Animal, v. 15, 100084, 2021.| Biblioteca(s): Embrapa Gado de Leite. |
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| 9. | | SILVA, A. A.; SILVA, F. F.; SILVA, D. A.; SILVA, H. T.; COSTA, C. N.; LOPES, P. S.; VERONEZE, R.; THOMPSON, G.; CARVALHEIRA, J. Genotype imputation strategies for Portuguese Holstein cattle using different SNP panels. Czech Journal of Animal Science, v. 64, n. 9, p. 377-386, 2019.| Biblioteca(s): Embrapa Gado de Leite. |
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| 10. | | SILVA, A. A.; SILVA, D. A.; LOPES, P. S.; SILVA, H. T.; VERONEZE, R.; THOMPSON, G.; CARVALHEIRA, J.; COSTA, C. N. Genomic predictions including unknown parent groups for milk traits in Portuguese Holstein cattle. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 73., 2022, Porto. Book of abstracts... Rome: European Federation of Animal Science, 2022. p. 135.| Biblioteca(s): Embrapa Gado de Leite. |
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| 11. | | SILVA, A. A.; SILVA, D. A.; SILVA, F. F.; COSTA, C. N.; SILVA, H. T.; LOPES, P. S.; VERONEZE, R.; THOMPSON, G.; CARVALHEIRA, J. GWAS and gene networks for milk-related traits from test-day multiple lactations in Portuguese Holstein cattle. Journal of Applied Genetics, v. 61, p. 465-476, 2020.| Biblioteca(s): Embrapa Gado de Leite. |
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| 12. | | COSTA, E. V.; DINIZ, D. B.; VERONEZE, R.; RESENDE, M. D. V. de; AZEVEDO, C. F.; GUIMARÃES, S. E. F.; SILVA, F. F.; LOPES, P. S. Estimating additive and dominance variances for complex traits in pigs combining genomic and pedigree information. Genetics and Molecular Research, v. 14, n. 2, p. 6303-6311, June 2015.| Biblioteca(s): Embrapa Florestas. |
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| 13. | | SOARES, T. L. da S.; SANTOS, F. L. C.; PEIXOTO, M. G. C. D.; CARRARA, E. R.; BRUNELI, F. A. T.; VERONEZE, R.; LOPES, P. S. A interação genótipo-ambiente já afeta características leiteiras e idade ao primeiro parto em animais Guzerá. Revista Guzerate, ano 2, n. 2, p. 66-70, maio 2023.| Biblioteca(s): Embrapa Gado de Leite. |
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| 14. | | SILVA, A. A.; SILVA, D. A.; LOPES, P. S.; SILVA, H. T.; VERONEZE, R.; THOMPSON, G.; COSTA, C. N.; CARVALHEIRA, J. SNP substitution effects for SCS changes across environmental gradients in Portuguese dairy cattle. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 73., 2022, Porto. Book of abstracts... Rome: European Federation of Animal Science, 2022. p. 136.| Biblioteca(s): Embrapa Gado de Leite. |
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| 15. | | CARRARA, E. R.; LOPES, P. S.; REIS, A. C. Z.; SILVA, J. X.; DIAS, L. C. de C. M.; SCHULTZ, E. B.; MARQUES, D. B. D.; SILVA, D. A. da; VERONEZE, R.; ANDRADE, R. G.; PEIXOTO, M. G. C. D. NASA POWER satellite meteorological system is a good tool for obtaining estimates of the temperature-humidity index under Brazilian conditions compared to INMET weather stations data. International Journal of Biometeorology, v. 67, n. 7, p. 1273-1277, 2023.| Biblioteca(s): Embrapa Gado de Leite. |
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| 16. | | CARRARA, E. R.; PEIXOTO, M. G. C. D.; SILVA, A. A. da; BRUNELI, F. A. T.; VENTURA, H. T.; ZADRA, L. E. F.; JOSAHKIAN, L. A.; VERONEZE, R.; LOPES, P. S. Genomic prediction in Brazilian Guzerá cattle: application of a single-step approach to productive and reproductive traits. Tropical Animal Health and Production, v. 55, article 48, 2023.| Biblioteca(s): Embrapa Gado de Leite. |
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| 17. | | DUARTE, D. A. S.; FORTES, M. R. S.; DUARTE, M. de S.; GUIMARÃES, S. E. F.; VERARDO, L. L.; VERONEZE, R.; RIBEIRO, A. M. F.; LOPES, P. S.; RESENDE, M. D. V. de; SILVA, F. F. e. Genome-wide association studies, meta-analyses and derived gene network for meat quality and carcass traits in pigs. Animal Production Science, v. 58, n. 6, p. 1100-1008, May 2018.| Biblioteca(s): Embrapa Florestas. |
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| 18. | | CARRARA, E. R.; PEIXOTO, M. G. C. D.; VERONEZE, R.; SILVA, F. F. e; RAMOS, P. V. B.; BRUNELI, F. A. T.; ZADRA, L. E. F.; VENTURA, H. T.; JOSAHKIAN, L. A.; LOPES, P. S. Genetic study of quantitative traits supports the use of Guzerá as dual-purpose cattle. Animal Bioscience, v. 35, n. 7, p. 955-963, 2022.| Biblioteca(s): Embrapa Gado de Leite. |
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| 19. | | ROCHA, R. de F. B.; OTTO, P. I.; SILVA, M. V. G. B.; MARTINS, M. F.; MACHADO, M. A.; VERONEZE, R.; LEANDRO, F. D.; PEREIRA, S. M.; GUIMARÃES, S. E. F.; PANETTO, J. C. do C. Repeatability and random regression models to estimate genetic parameters for oocyte and embryo production in the Gir breed. Animal Production Science, v. 62, n. 17, p. 1661-1670, 2022.| Biblioteca(s): Embrapa Gado de Leite. |
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| 20. | | OTTO, P. I.; GUIMARÃES, S. E. F.; VERARDO, L. L.; AZEVEDO, A. L. S.; VANDENPLAS, J.; SOARES, A. C. C.; SEVILLANO, C. A.; VERONEZE R; PIRES, M. de F. A.; FREITAS, C. de; PRATA, M. C. de A.; FURLONG, J.; VERNEQUE, R. da S.; MARTINS, M. F.; PANETTO, J. C. do C.; CARVALHO, W. A.; GOBO, D. O. R.; SILVA, M. V. G. B.; MACHADO, M. A. Genome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle: A deeper look into this intricate mechanism. Journal of Dairy Science, v. 101, n. 12, p. 11020-11032, 2018.| Biblioteca(s): Embrapa Gado de Leite. |
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| Registros recuperados : 20 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
18/12/2018 |
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Data da última atualização: |
24/01/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
OTTO, P. I.; GUIMARÃES, S. E. F.; VERARDO, L. L.; AZEVEDO, A. L. S.; VANDENPLAS, J.; SOARES, A. C. C.; SEVILLANO, C. A.; VERONEZE R; PIRES, M. de F. A.; FREITAS, C. de; PRATA, M. C. de A.; FURLONG, J.; VERNEQUE, R. da S.; MARTINS, M. F.; PANETTO, J. C. do C.; CARVALHO, W. A.; GOBO, D. O. R.; SILVA, M. V. G. B.; MACHADO, M. A. |
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Afiliação: |
PAMELA I. OTTO, UFV; SIMONE ELIZA FACIONI GUIMARAES, UFV; LUCAS L. VERARDO, UFV; ANA LUISA SOUSA AZEVEDO, CNPGL; J. VANDENPLAS, Wageningen University; ALINE C. C. SOARES, UFV; CLAUDIA A. SEVILLANO, Wageningen University; Topigs Norsvin Research Center, Beuningen; RENATA VERONEZE, UFV; MARIA DE FATIMA AVILA PIRES, CNPGL; CELIO DE FREITAS, CNPGL; MARCIA CRISTINA DE AZEVEDO PRATA, CNPGL; JOHN FURLONG, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; MARTA FONSECA MARTINS, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; WANESSA ARAUJO CARVALHO, CNPGL; DIEGO O. R. GOBO, UFV; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARCO ANTONIO MACHADO, CNPGL. |
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Título: |
Genome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle: A deeper look into this intricate mechanism. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Journal of Dairy Science, v. 101, n. 12, p. 11020-11032, 2018. |
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DOI: |
10.3168/jds.2017-14223 |
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Idioma: |
Inglês |
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Conteúdo: |
ABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network allowed the identification of genes involved with immune functions (MYO5A, TREML1, and PRSS16). In resistant animals, the average proportion of animals showing significant SNPs with paternal and maternal alleles originated from Gir breed was 44.8% whereas the proportion of animals with both paternal and maternal alleles originated from Holstein breed was 11.3%. Susceptible animals showing both paternal and maternal alleles originated from Holstein breed represented 44.6% on average, whereas both paternal and maternal alleles originated from Gir breed animals represented 9.3%. This study allowed us to identify candidate genes for tick resistance in Gir × Holstein crossbreds in both rainy and dry seasons. According to the origin of alleles analysis, we found that most animals classified as resistant showed 2 alleles from Gir breed, while the susceptible ones showed alleles from Holstein. Based on these results, the identified genes may be thoroughly investigated in additional experiments aiming to validate their effects on tick resistance phenotype in cattle. MenosABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network a... Mostrar Tudo |
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Palavras-Chave: |
Breed of origin; Gene network; Gir × Holstein crossbred. |
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Thesaurus NAL: |
Genetic variance. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 03793naa a2200397 a 4500
001 2101869
005 2023-01-24
008 2018 bl uuuu u00u1 u #d
024 7 $a10.3168/jds.2017-14223$2DOI
100 1 $aOTTO, P. I.
245 $aGenome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle$bA deeper look into this intricate mechanism.$h[electronic resource]
260 $c2018
520 $aABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network allowed the identification of genes involved with immune functions (MYO5A, TREML1, and PRSS16). In resistant animals, the average proportion of animals showing significant SNPs with paternal and maternal alleles originated from Gir breed was 44.8% whereas the proportion of animals with both paternal and maternal alleles originated from Holstein breed was 11.3%. Susceptible animals showing both paternal and maternal alleles originated from Holstein breed represented 44.6% on average, whereas both paternal and maternal alleles originated from Gir breed animals represented 9.3%. This study allowed us to identify candidate genes for tick resistance in Gir × Holstein crossbreds in both rainy and dry seasons. According to the origin of alleles analysis, we found that most animals classified as resistant showed 2 alleles from Gir breed, while the susceptible ones showed alleles from Holstein. Based on these results, the identified genes may be thoroughly investigated in additional experiments aiming to validate their effects on tick resistance phenotype in cattle.
650 $aGenetic variance
653 $aBreed of origin
653 $aGene network
653 $aGir × Holstein crossbred
700 1 $aGUIMARÃES, S. E. F.
700 1 $aVERARDO, L. L.
700 1 $aAZEVEDO, A. L. S.
700 1 $aVANDENPLAS, J.
700 1 $aSOARES, A. C. C.
700 1 $aSEVILLANO, C. A.
700 1 $aVERONEZE R
700 1 $aPIRES, M. de F. A.
700 1 $aFREITAS, C. de
700 1 $aPRATA, M. C. de A.
700 1 $aFURLONG, J.
700 1 $aVERNEQUE, R. da S.
700 1 $aMARTINS, M. F.
700 1 $aPANETTO, J. C. do C.
700 1 $aCARVALHO, W. A.
700 1 $aGOBO, D. O. R.
700 1 $aSILVA, M. V. G. B.
700 1 $aMACHADO, M. A.
773 $tJournal of Dairy Science$gv. 101, n. 12, p. 11020-11032, 2018.
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