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| Registros recuperados : 47 | |
| 3. |  | SOUZA, I.; SOARES, J.; VENTURA, R.; PEIXOTO, R.; SANTO, I. P.; BAVAY, C.; LUZ, L. DIPUC - Diagnóstico participativo de unidades de conservação. In: CONGRESSO BRASILEIRO DE UNIDADES DE CONSERVAÇÃO, 3., 2002, Fortaleza. Anais. Fortaleza: Rede Nacional Pró-Unidades de Conservação: Fundação O Boticário de Proteção à Natureza, 2002. p. 3-12. Trabalhos técnicos.| Biblioteca(s): Embrapa Florestas. |
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| 5. | | NASCIMENTO, G. B.; VENTURA, R. V.; LEDUR, M. C.; SAVEGNAGO, R. P.; SENO, L. de O.; MUNARI, D. P. Inbreeding effect and genotyping strategies for genomic selection in simulated data. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 41. ISAFG 2013. AB 34.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 7. | | CARRARA, E. R.; LOPES, P. S.; PEREZ, B. C.; VENTURA, R. V.; JOSAHKIAN, L. A.; PEIXOTO, M. G. C. D. Inbreeding and its effects on milk, growth, and reproductive traits in Guzerá cattle clustered by genetic similarity. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 56., 2021, Florianópolis. Animal science: challenges in production and sustainability: proceedings... Brasília, DF: Sociedade Brasileira de Zootecnia, 2021. p. 336. Evento virtual.| Biblioteca(s): Embrapa Gado de Leite. |
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| 10. | | VENTURA, H. T.; SILVA, F. F e; VARONA, L.; FIGUEIREDO, E. A. P. de; COSTA, E. V.; SILVA, L. P. da; VENTURA. R.; LOPES, P. S. Comparing multi-trait Poisson and Gaussian Bayesian models for genetic evaluation of litter traits in pigs. Livestock Science, v. 176, p. 47-53, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 11. | | FREITAS, L. S.; SILVA, M. A.; VERNEQUE, R. S.; SANTOS, G. G.; CORRÊA, G. S.; VALENTE, B. D.; PEIXOTO, M. G. C. D.; VENTURA, R. V. Comparação de modelos de regressão aleatória, para avaliação genética da produção de leite no dia do controle de vacas Guzerá. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 7., 2008, São Carlos. Anais... São Carlos: SBMA, 2008. 1 CD.| Biblioteca(s): Embrapa Gado de Leite. |
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| 12. | | BUZANSKAS, M. E.; GROSSI, D. A.; SCHENKEL, D. A.; VENTURA, R.; REGITANO, L. C. de A.; ALENCAR, M. M. de; MUNARI, D. P. Genome wide association analysis for birth and weaning weight in Canchim beef cattle. In: ANNUAL MEETING BRAZILIAN SOCIETY OF ANIMAL SCIENCE, 50., 2013, Campinas. The integration of Knowledge in animal production - Abstracts. Campinas: SBZ, 2013. 1 CD-ROM| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 13. | | OLIVEIRA JUNIOR, G. A.; VENTURA, R.; FREITAS, B. G. de; SANTANA, M. H. A.; SILVA, M. V. G. B.; FERRAZ, J. B. S.; GARRICK, D. J. Genome-wide association study in reproductive trait of Nellore heifers. In: PLANT & ANIMAL GENOME, 24., 2016, San Diego. [Proceedings...] San Diego: [s.n.], 2016.| Biblioteca(s): Embrapa Gado de Leite. |
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| 14. | | VIZONA, R. G.; PEREZ, B. da C.; PEIXOTO, M. G. C. D.; VIANA, J. H. M.; VENTURA, R. V.; VERCESI FILHO, A. E.; BALIEIRO, J. C. de C. Genetic analysis of in-vitro embryo production traits in Dairy Gir cattle. Theriogenology, v. 148, p. 149-161, 2020.| Biblioteca(s): Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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| 15. | | CHUD, T. C. S.; VENTURA, R. V.; SCHENKEL. F. S.; URBINATI, I.; CARVALHEIRO, R.; REGITANO, L. C. de A.; MARCONDES, C. R.; MINARI, D. P. Accuracy of genotype imputation in Canchim cattle using FImpute and Beagle software., In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Abstract... Guarujá:[ s.n.], 2013. AB.20.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 17. | | BUZANSKAS, M. E.; GROSSI, D. A.; SCHENKEL, D. A.; VENTURA, R.; REGITANO, L. C. de A.; ALENCAR, M. M. de; MUNARI, D. P. Linkage disequilibrium analysis in Canchim beef cattle. In: ANNUAL MEETING BRAZILIAN SOCIETY OF ANIMAL SCIENCE, 50., 2013, Campinas. The integration of Knowledge in animal production - Abstracts. Campinas: SBZ, 2013. 1 CD-ROM| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 18. | | BUZANSKAS, M. E.; VENTURA, R. V.; REGITANO, L. C. de A.; SCHENKEL, F. S.; ALENCAR, M. M. de; MUNARI, D. P. Estudo de associações genômicas para idade ao primeiro e segundo parto em bovinos da raça Canchim. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 10., 2013, Uberaba. Anais... Belo Horizonte: SBMA, 2013. 3 p.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 19. | | SIMONELLI, S. M.; SILVA, M. A.; SILVA, L. O. C. da; PEREIRA, J. C. C.; SOUZA, J. E. R.; VENTURA, R. V.; VALENTE, B. D. Critérios de seleção para características de crescimento em bovinos da raça Nelore. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Belo Horizonte, v. 56, n. 3, p. 374-384, jun. 2004. Título em inglês: Selection criteria for growth traits in Nellore cattle.| Biblioteca(s): Embrapa Gado de Corte. |
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| 20. | | FRIDRICH, A. B.; SILVA, M. A.; VALENTE, B. D.; SOUSA, J. E. R.; CORRÊA, G. S. S.; FERREIRA, I. C.; VENTURA, R. V.; SILVA, L. O. C. Interação genótipo x ambiente e estimativas de parâmetros genéticos dos pesos aos 205 e 365 dias de idade de bovinos Nelore. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Belo Horizonte, v. 60, n. 4, p. 917-925, ago. 2008.| Biblioteca(s): Embrapa Gado de Corte. |
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| Registros recuperados : 47 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
28/11/2018 |
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Data da última atualização: |
24/01/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
PERIPOLLI, E.; STAFUZZA, N. B.; MUNARI, D. P.; LIMA, A. L. F.; IRGANG, R.; MACHADO, M. A.; PANETTO, J. C. do C.; VENTURA, R. V.; BALDI, F.; SILVA, M. V. G. B. |
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Afiliação: |
ELISA PERIPOLLI, UNESP; NEDENIA BONVINO STAFUZZA, UNESP; DANÍSIO PRADO MUNARI, UNESP / CNPQ; ANDRÉ LUÍS FERREIRA LIMA, UFSC; RENATO IRGANG, UFSC; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; RICARDO VIEIRA VENTURA, USP / Beef Improvement Opportunities, Canada / University of Guelph, Canada; FERNANDO BALDI, UNESP; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
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Título: |
Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
BMC Genomics, v. 19, n. 34, 2018. |
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Páginas: |
13 p. |
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DOI: |
10.1186/s12864-017-4365-3 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract BACKGROUND: Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i) to investigate genome-wide autozygosity to identify and characterize ROH patterns in Gyr dairy cattle genome; (ii) identify ROH islands for gene content and enrichment in segments shared by more than 50% of the samples, and (iii) compare estimates of molecular inbreeding calculated from ROH (FROH), genomic relationship matrix approach (FGRM) and based on the observed versus expected number of homozygous genotypes (FHOM), and from pedigree-based coefficient (FPED). RESULTS: ROH were identified in all animals, with an average number of 55.12 ± 10.37 segments and a mean length of 3.17 Mb. Short segments (ROH1-2 Mb) were abundant through the genomes, which accounted for 60% of all segments identified, even though the proportion of the genome covered by them was relatively small. The findings obtained in this study suggest that on average 7.01% (175.28 Mb) of the genome of this population is autozygous. Overlapping ROH were evident across the genomes and 14 regions were identified with ROH frequencies exceeding 50% of the whole population. Genes associated with lactation (TRAPPC9), milk yield and composition (IRS2 and ANG), and heat adaptation (HSF1, HSPB1, and HSPE1), were identified. Inbreeding coefficients were estimated through the application of FROH, FGRM, FHOM, and FPED approaches. FPED estimates ranged from 0.00 to 0.327 and FROH from 0.001 to 0.201. Low to moderate correlations were observed between FPED-FROH and FGRM-FROH, with values ranging from -0.11 to 0.51. Low to high correlations were observed between FROH-FHOM and moderate between FPED-FHOM and FGRM-FHOM. Correlations between FROH from different lengths and FPED gradually increased with ROH length. CONCLUSIONS: Genes inside ROH islands suggest a strong selection for dairy traits and enrichment for Gyr cattle environmental adaptation. Furthermore, low FPED-FROH correlations for small segments indicate that FPED estimates are not the most suitable method to capture ancient inbreeding. The existence of a moderate correlation between larger ROH indicates that FROH can be used as an alternative to inbreeding estimates in the absence of pedigree records. MenosAbstract BACKGROUND: Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i) to investigate genome-wide autozygosity to identify and characterize ROH patterns in Gyr dairy cattle genome; (ii) identify ROH islands for gene content and enrichment in segments shared by more than 50% of the samples, and (iii) compare estimates of molecular inbreeding calculated from ROH (FROH), genomic relationship matrix approach (FGRM) and based on the observed versus expected number of homozygous genotypes (FHOM), and from pedigree-based coefficient (FPED). RESULTS: ROH were identified in all animals, with an average number of 55.12 ± 10.37 segments and a mean length of 3.17 Mb. Short segments (ROH1-2 Mb) were abundant through the genomes, which accounted for 60% of all segments identified, even though the proportion of the genome covered by them was relatively small. The findings obtained in this study suggest that on average 7.01% (175.28 Mb) of the genome of this population is autozygous. Overlapping ROH were evident across the genomes and 14 regions were identified with ROH frequencies exceeding 50% of the whole population. Genes associated with lactation (TRAPPC9), milk yield and composition (IRS2 and ANG), and heat adaptation (HSF1, HSPB1, and HSPE1), were identified. Inbreeding coefficient... Mostrar Tudo |
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Palavras-Chave: |
Dairy traits; Inbreeding coefficients; ROH islands. |
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Thesagro: |
Bos Indicus. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/187250/1/Cnpgl-2018-BMC-Gen-Machado-Assessment.pdf
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Marc: |
LEADER 03293naa a2200301 a 4500
001 2100275
005 2023-01-24
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1186/s12864-017-4365-3$2DOI
100 1 $aPERIPOLLI, E.
245 $aAssessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle.$h[electronic resource]
260 $c2018
300 $a13 p.
520 $aAbstract BACKGROUND: Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i) to investigate genome-wide autozygosity to identify and characterize ROH patterns in Gyr dairy cattle genome; (ii) identify ROH islands for gene content and enrichment in segments shared by more than 50% of the samples, and (iii) compare estimates of molecular inbreeding calculated from ROH (FROH), genomic relationship matrix approach (FGRM) and based on the observed versus expected number of homozygous genotypes (FHOM), and from pedigree-based coefficient (FPED). RESULTS: ROH were identified in all animals, with an average number of 55.12 ± 10.37 segments and a mean length of 3.17 Mb. Short segments (ROH1-2 Mb) were abundant through the genomes, which accounted for 60% of all segments identified, even though the proportion of the genome covered by them was relatively small. The findings obtained in this study suggest that on average 7.01% (175.28 Mb) of the genome of this population is autozygous. Overlapping ROH were evident across the genomes and 14 regions were identified with ROH frequencies exceeding 50% of the whole population. Genes associated with lactation (TRAPPC9), milk yield and composition (IRS2 and ANG), and heat adaptation (HSF1, HSPB1, and HSPE1), were identified. Inbreeding coefficients were estimated through the application of FROH, FGRM, FHOM, and FPED approaches. FPED estimates ranged from 0.00 to 0.327 and FROH from 0.001 to 0.201. Low to moderate correlations were observed between FPED-FROH and FGRM-FROH, with values ranging from -0.11 to 0.51. Low to high correlations were observed between FROH-FHOM and moderate between FPED-FHOM and FGRM-FHOM. Correlations between FROH from different lengths and FPED gradually increased with ROH length. CONCLUSIONS: Genes inside ROH islands suggest a strong selection for dairy traits and enrichment for Gyr cattle environmental adaptation. Furthermore, low FPED-FROH correlations for small segments indicate that FPED estimates are not the most suitable method to capture ancient inbreeding. The existence of a moderate correlation between larger ROH indicates that FROH can be used as an alternative to inbreeding estimates in the absence of pedigree records.
650 $aBos Indicus
653 $aDairy traits
653 $aInbreeding coefficients
653 $aROH islands
700 1 $aSTAFUZZA, N. B.
700 1 $aMUNARI, D. P.
700 1 $aLIMA, A. L. F.
700 1 $aIRGANG, R.
700 1 $aMACHADO, M. A.
700 1 $aPANETTO, J. C. do C.
700 1 $aVENTURA, R. V.
700 1 $aBALDI, F.
700 1 $aSILVA, M. V. G. B.
773 $tBMC Genomics$gv. 19, n. 34, 2018.
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Embrapa Gado de Leite (CNPGL) |
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