Data/hora: 04/06/2024 06:44:15

Biblioteca(s): | Embrapa Clima Temperado.
Tipo da produção científica: | Artigo em Periódico Indexado
Circulação/Nível: | B - 2
Data corrente: | 16/03/2021
Data da última atualização: | 10/06/2022
Autoria: | OLIVEIRA, P. S.; SOARES, M. S. P.; BONA, N. P.; SILVA, P. G. DA; MENDONÇA, L. T.; VIEIRA, A.; DAL-PIZZOL, F.; VIZZOTTO, M.; LENCINA, C. L.; SPANEVELLO, R. M.; STEFANELLO, F. M.
Afiliação: | PATHISE SOUTO OLIVEIRA, UFPEL; MAYARA SANDRIELLY PEREIRA SOARES, UFPEL; NATÁLIA PONTES BONA, UFPEL; PÂMELA GONÇALVES DA SILVA, UFPEL; LORENÇO TORRES MENDONÇA, UFPEL; ANDRIELE VIEIRA, UNIVERSIDADE DO EXTREMO SUL CATARINENSE; FELIPE DAL-PIZZOL, UNIVERSIDADE DO EXTREMO SUL CATARINENSE; MARCIA VIZZOTTO, CPACT; CLAITON LEONETI LENCINA, UFPEL; ROSELIA MARIA SPANEVELLO, UFPEL; FRANCIELI MORO STEFANELLO, UFPEL.
Título: | Brazilian native fruit extracts act as preventive agents modulating the purinergic and cholinergic signalling in blood cells and serum in a rat model of metabolic syndrome.
Ano de publicação: | 2020
Fonte/Imprenta: | Archives of Physiology and Biochemistry, 2020.
Páginas: | 8 p.
ISSN: | 1744-4160
DOI: | 10.1080/13813455.2020.1743723
Idioma: | Inglês
Conteúdo: | In this study, we evaluated the effects of native fruit extracts on inflammatory and thromboregulatory parameters in animal model of metabolic syndrome (MetS) induced by highly palatable diet (HPD). Rats were divided into 4 experimental groups: standard chow, HPD, HPD and Psidium cattleianum extract, and HPD and Eugenia uniflora extract. HPD increased serum interleukin-6 (IL-6) levels. On the other hand, this change was prevented by extracts. HPD decreased NTPDase activity in lymphocytes and platelets and 50-nucleotidase in platelets. Treatment with extracts prevented these changes. An increase in adenosine deaminase (ADA) activity was prevented by E. uniflora in lymphocytes and serum of rats. Fruit extracts prevented the increase in the activity of acetylcholinesterase (AChE) in lymphocytes and butyrylcholinesterase (BuChE) in serum induced by the HPD. Brazilian native fruit extracts have anti-inflammatory and antithrombotic effects, demonstrating therapeutic potential in the prevention of complications associated with MetS.
Palavras-Chave: | Fruta nativa; Red fruits; Síndrome metabólica.
Thesagro: | Extrato; Extrato de Fruta; Fruta.
Categoria do assunto: | --
Registro original: | Embrapa Clima Temperado (CPACT)
Exemplares: | CPACT - (21896-1) - UPC - AP - DD -  -  -  - DIS