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| Registros recuperados : 10 | |
| 3. |  | JARDIM, A. M. da R. F.; SILVA, T. G. F. da; SOUZA, L. S. B. de; ARAÚJO JÚNIOR, G. do N.; ALVES, H. K. M. N.; SOUZA, M. de S.; ARAUJO, G. G. L. de; MOURA, M. S. B. de. Intercropping forage cactus and sorghum in a semi-arid environment improves biological efficiency and competitive ability through interspecific complementarity. Journal of Arid Environments, v. 188, 2021.| Biblioteca(s): Embrapa Semiárido. |
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| 4. | | SOUZA, M. de S.; SILVA, T. G. F. da; SOUZA, L. S. B. de; ALVES, H. K. M. N.; LEITE, R, M. C.; SOUZA, C. A. A. de; ARAUJO, G. G. L. de; CAMPOS, F. S.; SILVA, M. J. da; SOUZA, P. J. de O. P. de. Growth, phenology and harvesting time of cactus-millet intercropping system under biotic mulching. Archives of Agronomy and Soil Science, v. 68, n. 6. 764-778, 2020.| Biblioteca(s): Embrapa Semiárido. |
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| 5. | | OLIVEIRA, P. S. N. de; COUTINHO, L. L.; CESAR, A. S. M.; DINIZ, W. J. da S.; SOUZA, M. de S.; ANDRADE, B. G.; KOLTES, J. E.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REECY, J. M.; REGITANO, L. C. de A. Co-expression networks reveal potential regulatory roles of miRNAs in fatty acid composition of nelore cattle. Frontiers in Genetics, v. 10, p. 1-14, July 2019. Article 651. Na publicação: Adhemar Zerlotini, Luciana C.A. Regitano.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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| 6. | | SILVA, G. I. N.; JARDIM, A. M. da R. F.; SOUZA, M. de S.; ARAÚJO JÚNIOR, G. do N.; MORAIS, J. E. F. de; SOUZA, L. S. B. de; SOUZA, C. A. A. de; ALVES, C. P.; ARAUJO, G. G. L. de; MONTENEGRO, A. A. de A.; LIMA, B. L. de C.; SILVA, T. G. F. da. Combined agricultural practices in millet and cactus: phyllochron, structural characteristics and relations with yield. Scientia Agrícola, v. 80, e20220046, 2023.| Biblioteca(s): Embrapa Semiárido. |
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| 7. | | ARAÚJO JÚNIOR, G. do N.; SILVA, T. G. F. da; SOUZA, L. S. B. de; SOUZA, M. de S.; ARAUJO, G. G. L. de; MOURA, M. S. B. de; SANTOS, J. P. A. de S.; JARDIM, A. M. da R. F.; ALVES, C. P.; ALVES, H. K. M. N. Productivity, bromatological composition and economic benefits of using irrigation in the forage cactus under regulated deficit irrigation in a semiarid environment. Bragantia, v. 80, jan. 2021.| Biblioteca(s): Embrapa Semiárido. |
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| 8. | | LIMA, A. O. de; KOLTES, J. E.; DINIZ, W. J. S.; OLIVEIRA, P. S. N. de; CESAR, A. S. M.; TIZIOTO, P. L.; AFONSO, J.; SOUZA, M. de S.; PETRINI, J.; ROCHA, M. I. P.; CARDOSO, T. F.; ZERLOTINI NETO, A.; COUTINHO, L. L.; MOURÃO, G. B.; REGITANO, L. C. de A. Potential biomarkers for feed efficiency-related traits in nelore cattle identified by co-expression network and integrative genomics analyses. Frontiers in Genetics, v. 11, p. 1-14, Mar. 2020. Article 189. Na publicação: Luciana C. A. Regitano.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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| 9. | | JARDIM, A. M. da R. F; SANTOS, H. R. B.; ALVES, H. K. M. N.; SILVA, S. L. F.; SOUZA, L. S. B. de; ARAÚJO JÚNIOR, G. do N.; SOUZA, M. de S.; ARAUJO, G. G. L. de; SOUZA, C. A. A. de; SILVA, T. G. F. da. Genotypic differences relative photochemical activity, inorganic and organic solutes and yield performance in clones of the forage cactus under semi-arid environment. Plant Physiology and Biochemistry, v. 162, p. 421-430, 2021.| Biblioteca(s): Embrapa Semiárido. |
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| 10. | | AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A. Genetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach. Scientific Reports, v. 10, n. 1, p. 1-16, 2020 Article: 8436.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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| Registros recuperados : 10 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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Data corrente: |
08/09/2020 |
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Data da última atualização: |
10/09/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A. |
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Afiliação: |
JULIANA AFONSO, UFSCar; MARINA RUFINO SALINAS FORTES, The University of Queensland; ANTONIO REVERTER, Agriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Brisbane; WELLISON JARLES DA SILVA DINIZ, UFSCar; ALINE SILVA MELLO CESAR, Esalq/USP; ANDRESSA OLIVEIRA DE LIMA, UFSCar; JULIANA PETRINI, UNIFAL; MARCELA M. DE SOUZA, Iowa State University; LUIZ LEHMANN COUTINHO, Esalq/USP; GERSON BARRETO MOURÃO, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; CAIO FERNANDO GROMBONI, Bahia Federal Institute of Education, Science and Technology, Ilhéus; ANA RITA ARAÚJO NOGUEIRA; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Genetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Scientific Reports, v. 10, n. 1, p. 1-16, 2020 |
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DOI: |
https://doi.org/10.1038/s41598-020-65454-7 |
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Idioma: |
Inglês |
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Notas: |
Article: 8436. |
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Conteúdo: |
Mineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals. MenosMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators describe... Mostrar Tudo |
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Palavras-Chave: |
Expressão gênica. |
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Thesagro: |
Bos Indicus; Gado Nelore. |
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Thesaurus NAL: |
Cattle; Gene expression. |
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Categoria do assunto: |
--
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/215819/1/AP-Genetic-regulators-2020.pdf
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Marc: |
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024 7 $ahttps://doi.org/10.1038/s41598-020-65454-7$2DOI
100 1 $aAFONSO, J.
245 $aGenetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach.$h[electronic resource]
260 $c2020
500 $aArticle: 8436.
520 $aMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals.
650 $aCattle
650 $aGene expression
650 $aBos Indicus
650 $aGado Nelore
653 $aExpressão gênica
700 1 $aFORTES, M. R. S.
700 1 $aREVERTER, A.
700 1 $aDINIZ, W. J. da S.
700 1 $aCESAR, A. S. M.
700 1 $aLIMA, A. O. de
700 1 $aPETRINI, J.
700 1 $aSOUZA, M. de S.
700 1 $aCOUTINHO, L. L.
700 1 $aMOURÃO, G. B.
700 1 $aZERLOTINI NETO, A.
700 1 $aGROMBONI, C. F.
700 1 $aNOGUEIRA, A. R. A.
700 1 $aREGITANO, L. C. de A.
773 $tScientific Reports$gv. 10, n. 1, p. 1-16, 2020
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Embrapa Agricultura Digital (CNPTIA) |
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