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Registro Completo |
Biblioteca(s): |
Embrapa Soja. |
Data corrente: |
15/02/2012 |
Data da última atualização: |
05/08/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CARRARA, V. da S.; AMADO, C. B.; MELO, J. O. de; MANDARINO, J. M. G.; CORTEZ, D. A. G. |
Afiliação: |
VANESSA DA SILVA CARRARA, UEM; CIOMAR BERSANI AMADO, UEM; JULIANA OLIVEIRA DE MELO, UEM; JOSE MARCOS GONTIJO MANDARINO, CNPSO; DIÓGENES APARÍCIO GARCIA CORTEZ, UEM. |
Título: |
Evaluation of soybean methanol fraction on acute inflammation. |
Ano de publicação: |
2011 |
Fonte/Imprenta: |
Journal of Medicinal Food, v. 14, n. 12, p. 1570-1575, 2011. |
DOI: |
10.1089/jmf.2010.0320 |
Idioma: |
Inglês |
Conteúdo: |
Soybeans have been of interest of researchers because of the presence of isoflavones, a subclass of flavonoids, which have demonstrated anti-inflammatory activity. The aim of this study was investigate the anti-inflammatory activity of the methanol fraction from soybean, which contains mainly isoflavone glucosides and malonylglucosides. The anti-inflammatory activity of the methanol fraction from soybean was studied using croton oil?induced mouse ear edema and carrageenan-induced pleurisy models. The methanol fraction inhibited the ear edema in a dose-dependent manner: 0.625 mg/kg by 44.23% (P < .05), 1.25 mg/kg by 60.68% (P < .01), and 2.5 mg/kg by 65.68% (P < .01). Myeloperoxidase enzyme activity was reduced at the dose of 2.5 mg/kg (64.79%, P < .05). No effects were seen on carrageenan-induced pleurisy at different doses of the methanol fraction (100 or 400 mg/kg). These results demonstrated that the methanol fraction containing conjugated isoflavones showed topical anti-inflammatory activity. There was no acute toxicity in Swiss mice after oral administration of the fraction, at doses of 1,000, 2,000, 3,000, and 4,000 mg/kg. |
Thesagro: |
Antiinflamatório; Soja. |
Thesaurus Nal: |
Acute toxicity; Anti-inflammatory activity; Isoflavones; Soybeans. |
Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
Marc: |
LEADER 01858naa a2200253 a 4500 001 1915573 005 2017-08-05 008 2011 bl uuuu u00u1 u #d 024 7 $a10.1089/jmf.2010.0320$2DOI 100 1 $aCARRARA, V. da S. 245 $aEvaluation of soybean methanol fraction on acute inflammation. 260 $c2011 520 $aSoybeans have been of interest of researchers because of the presence of isoflavones, a subclass of flavonoids, which have demonstrated anti-inflammatory activity. The aim of this study was investigate the anti-inflammatory activity of the methanol fraction from soybean, which contains mainly isoflavone glucosides and malonylglucosides. The anti-inflammatory activity of the methanol fraction from soybean was studied using croton oil?induced mouse ear edema and carrageenan-induced pleurisy models. The methanol fraction inhibited the ear edema in a dose-dependent manner: 0.625 mg/kg by 44.23% (P < .05), 1.25 mg/kg by 60.68% (P < .01), and 2.5 mg/kg by 65.68% (P < .01). Myeloperoxidase enzyme activity was reduced at the dose of 2.5 mg/kg (64.79%, P < .05). No effects were seen on carrageenan-induced pleurisy at different doses of the methanol fraction (100 or 400 mg/kg). These results demonstrated that the methanol fraction containing conjugated isoflavones showed topical anti-inflammatory activity. There was no acute toxicity in Swiss mice after oral administration of the fraction, at doses of 1,000, 2,000, 3,000, and 4,000 mg/kg. 650 $aAcute toxicity 650 $aAnti-inflammatory activity 650 $aIsoflavones 650 $aSoybeans 650 $aAntiinflamatório 650 $aSoja 700 1 $aAMADO, C. B. 700 1 $aMELO, J. O. de 700 1 $aMANDARINO, J. M. G. 700 1 $aCORTEZ, D. A. G. 773 $tJournal of Medicinal Food$gv. 14, n. 12, p. 1570-1575, 2011.
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Registro original: |
Embrapa Soja (CNPSO) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Hortaliças. Para informações adicionais entre em contato com cnph.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Hortaliças. |
Data corrente: |
23/06/1999 |
Data da última atualização: |
23/06/1999 |
Autoria: |
LIMA, J. A.; SOUZA, A. F.; FERREIRA, P. E. |
Afiliação: |
EMBRAPA-CNPH, Brasilia, DF. |
Título: |
Adubacao potassica na producao de sementes de cenoura. |
Ano de publicação: |
1985 |
Fonte/Imprenta: |
Horticultura Brasileira, Brasilia, v.3, n.1, p.75, maio 1985. |
Idioma: |
Português |
Notas: |
Resumo. |
Palavras-Chave: |
Brasil; Brasilia; Carrot; Cultivar Brasilia; Distrito Federal; Potash fertilizers; Production. |
Thesagro: |
Cenoura; Cerrado; Daucus Carota; Fertilizante Potássico; Produção; Semente. |
Thesaurus NAL: |
Brazil; seeds. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00819naa a2200325 a 4500 001 1764328 005 1999-06-23 008 1985 bl uuuu u00u1 u #d 100 1 $aLIMA, J. A. 245 $aAdubacao potassica na producao de sementes de cenoura. 260 $c1985 500 $aResumo. 650 $aBrazil 650 $aseeds 650 $aCenoura 650 $aCerrado 650 $aDaucus Carota 650 $aFertilizante Potássico 650 $aProdução 650 $aSemente 653 $aBrasil 653 $aBrasilia 653 $aCarrot 653 $aCultivar Brasilia 653 $aDistrito Federal 653 $aPotash fertilizers 653 $aProduction 700 1 $aSOUZA, A. F. 700 1 $aFERREIRA, P. E. 773 $tHorticultura Brasileira, Brasilia$gv.3, n.1, p.75, maio 1985.
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