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| 1. |  | VIANA, E. S.; CAMPOS, M. E. M.; PONCE, A. R.; MANTOVANI, H. C.; VANETTI, M. C. D. Detecção de moléculas sinalizadoras de quorum sensing em biofilmes formados por Hafnia alvei isoladas de leite. In: SIMPÓSIO MINEIRO DE MICROBIOLOGIA DE ALIMENTOS, 3.; FÓRUM DE DEBATES SOBRE VIGILÂNCIA SANITÁRIA, 3., 2008, Viçosa, MG. Qualidade, segurança alimentar e sustentabilidade: quando? onde? como? por que?: anais. Viçosa, MG: sbCTA, 2008.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
18/03/2011 |
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Data da última atualização: |
10/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
SILVA, M. V. G. B.; SONSTEGARD, T. S.; THALLMAN, R. M.; CONNOR, E. E.; SCHNABEL, R. D.; TASSELL, C. P. V. |
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Afiliação: |
MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; Tad Stewart Sonstegard, USDA/ARS; RICHARD M. THALLMAN, USDA; ERIN E. CONNOR, USDA; ROBERT D. SCHNABEL, UNIVERSITY OF MISSOURI-COLUMBIA; CURT P. VAN TASSELL, USDA. |
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Título: |
Characterization of DGAT1 Allelic effects in a sample of north american holstein cattle. |
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Ano de publicação: |
2010 |
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Fonte/Imprenta: |
Animal Biotechnology, v. 21, p. 88-99, 2010. |
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DOI: |
https://doi.org/10.1080/10495390903504625 |
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Idioma: |
Inglês |
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Conteúdo: |
A putative causative mutation underlying a QTL was identified as a lysine to alanine non-conservative substitution at amino acid 232 of the gene encoding the acylCoA:diacylglycerol acyltransferase (DGAT1) protein. Our goal was to characterize the allelic substitution effects of this DGAT1 mutation in a large sample of Holstein bulls from North America. Statistically significant effects were identified for all of the milk production traits and somatic cell scores. Estimated average effects of substituting the lysine allele for the alanine variant on Holstein bull daughter yield deviations were −81 kg, 3.7 kg, −1.1 kg, 0.063%, 0.012%, and −0.023 units for milk yield, fat yield, protein yield, fat component, protein component, and SCS, respectively. These estimates were largely in agreement with previous studies; however, the magnitudes of the estimates were much smaller in this study. Impacts on economic indices for net merit, cheese merit, and fluid merit were modest. Because of the strong antagonism between fat and protein yield and how those traits influence economic indices, selection for DGAT1 genotypes will likely not find widespread application in the U.S. |
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Palavras-Chave: |
Substitution effect. |
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Thesaurus NAL: |
dairy cattle; milk production; quantitative trait loci. |
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Categoria do assunto: |
G Melhoramento Genético |
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Marc: |
LEADER 01943naa a2200241 a 4500
001 1881591
005 2022-08-10
008 2010 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1080/10495390903504625$2DOI
100 1 $aSILVA, M. V. G. B.
245 $aCharacterization of DGAT1 Allelic effects in a sample of north american holstein cattle.$h[electronic resource]
260 $c2010
520 $aA putative causative mutation underlying a QTL was identified as a lysine to alanine non-conservative substitution at amino acid 232 of the gene encoding the acylCoA:diacylglycerol acyltransferase (DGAT1) protein. Our goal was to characterize the allelic substitution effects of this DGAT1 mutation in a large sample of Holstein bulls from North America. Statistically significant effects were identified for all of the milk production traits and somatic cell scores. Estimated average effects of substituting the lysine allele for the alanine variant on Holstein bull daughter yield deviations were −81 kg, 3.7 kg, −1.1 kg, 0.063%, 0.012%, and −0.023 units for milk yield, fat yield, protein yield, fat component, protein component, and SCS, respectively. These estimates were largely in agreement with previous studies; however, the magnitudes of the estimates were much smaller in this study. Impacts on economic indices for net merit, cheese merit, and fluid merit were modest. Because of the strong antagonism between fat and protein yield and how those traits influence economic indices, selection for DGAT1 genotypes will likely not find widespread application in the U.S.
650 $adairy cattle
650 $amilk production
650 $aquantitative trait loci
653 $aSubstitution effect
700 1 $aSONSTEGARD, T. S.
700 1 $aTHALLMAN, R. M.
700 1 $aCONNOR, E. E.
700 1 $aSCHNABEL, R. D.
700 1 $aTASSELL, C. P. V.
773 $tAnimal Biotechnology$gv. 21, p. 88-99, 2010.
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Embrapa Gado de Leite (CNPGL) |
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