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| Registros recuperados : 6 | |
| 1. |  | OLIVEIRA, C.; BASSICHETO, M.; RIVERO, M.; SIPOLONI, V.; SOARES, J. K. C.; SILVA, G. F. da; VEIGA, T.; SOMAN, L. Chemical, biological, and genomic approaches the identification of antifungal metabolites from Penicillium setosum CMLD18. In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 2. | | CASTRO, G. dos S.; SOUSA, T.; YAMAGISHI, M. E. B.; SILVA, G. F. da; GARRETT, R.; SOMAN, L.; KOOLEN, H. Identification of new peptaibols in the strain of Trichoderma amazonicum MMSRG 38A isolated from açaí fruit. In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...]. Campinas: Galoá, 2023.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Amazônia Ocidental. |
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| 3. | | SILVA, J. C. da; NEVES, K.; LIMA, E.; PAZ, W. H. P.; SOMAN, L.; KOOLEN, H.; SILVA, G. F. da. Antimicrobial potential of Penicillium labradorum: genome mining and metabolomics analysis in the control of agricultural pathogens. In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 4. | | NEVES, K.; SILVA, J. C. da; LIMA, E.; SOMAN, L.; QUEIROZ, C.; KOOLEN, H.; SILVA, G. F. da. Prospecting for natural products from a new species of Streptomyces isolated from sediments of the Madeira River, Amazonas, Brazil. In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 5. | | BASSICHETO, M.; OLIVEIRA, C.; RIVERO, M.; SIPOLONI, V.; SOARES, J. K. C.; SILVA, G. F. da; JUSTO, G.; VEIGA, T.; SOMAN, L. Detection of antileukemia metabolites from P. limosum integrating genome mining, metabolomic analysis and cytotoxicity assays. In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 6. | | ARAÚJO JÚNIOR, M. B. de; SOUSA, T.; CASTRO, G. dos S.; SANTOS, V. S. dos; SOMAN, L.; HANADA, R. E.; SILVA, G. F. da; KOOLEN, H. Peptaibol production of a New Trichoderma species from the Amazon. In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| Registros recuperados : 6 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Amazônia Ocidental. |
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Data corrente: |
14/12/2023 |
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Data da última atualização: |
15/12/2023 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
BASSICHETO, M.; OLIVEIRA, C.; RIVERO, M.; SIPOLONI, V.; SOARES, J. K. C.; SILVA, G. F. da; JUSTO, G.; VEIGA, T.; SOMAN, L. |
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Afiliação: |
MILENA BASSICHETO, UNIVERSIDADE FEDERAL DE SÃO PAULO; CLÁUDIA OLIVEIRA, UNIVERSIDADE FEDERAL DE SÃO PAULO; MILENA RIVERO, UNIVERSIDADE FEDERAL DE SÃO PAULO; VICTOR SIPOLONI, UNIVERSIDADE FEDERAL DE SÃO PAULO; JULLIO KENNEDY CASTRO SOARES, UNIVERSIDADE FEDERAL DE SÃO PAULO; GILVAN FERREIRA DA SILVA, CPAA; GISELLE JUSTO, UNIVERSIDADE FEDERAL DE SÃO PAULO; THIAGO VEIGA, UNIVERSIDADE FEDERAL DE SÃO PAULO; LÍVIA SOMAN, UNIVERSIDADE FEDERAL DE SÃO PAULO. |
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Título: |
Detection of antileukemia metabolites from P. limosum integrating genome mining, metabolomic analysis and cytotoxicity assays. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
In: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023. |
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Idioma: |
Inglês |
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Conteúdo: |
Chemical dereplication and genome mining approaches were applied to detect cytotoxic metabolites produced by P. limosum CMLD 19 with anticancer potential against human leukemia cells. During the ongoing study, metabolites such as fumitremorgin and triprostatin were detected in the rice extract of P. limosum which showed 80% of cell inhibition for different human leukemia cell lines. |
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Palavras-Chave: |
Chemical dereplication; Cytotoxic metabolites. |
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Thesaurus NAL: |
Genome mining; Leukemia. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1159736/1/galoa-proceedings-bcnp-2023-173097.pdf
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Marc: |
LEADER 01285nam a2200253 a 4500
001 2159736
005 2023-12-15
008 2023 bl uuuu u00u1 u #d
100 1 $aBASSICHETO, M.
245 $aDetection of antileukemia metabolites from P. limosum integrating genome mining, metabolomic analysis and cytotoxicity assays.$h[electronic resource]
260 $aIn: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.; MEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá$c2023
520 $aChemical dereplication and genome mining approaches were applied to detect cytotoxic metabolites produced by P. limosum CMLD 19 with anticancer potential against human leukemia cells. During the ongoing study, metabolites such as fumitremorgin and triprostatin were detected in the rice extract of P. limosum which showed 80% of cell inhibition for different human leukemia cell lines.
650 $aGenome mining
650 $aLeukemia
653 $aChemical dereplication
653 $aCytotoxic metabolites
700 1 $aOLIVEIRA, C.
700 1 $aRIVERO, M.
700 1 $aSIPOLONI, V.
700 1 $aSOARES, J. K. C.
700 1 $aSILVA, G. F. da
700 1 $aJUSTO, G.
700 1 $aVEIGA, T.
700 1 $aSOMAN, L.
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Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
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